Improving target assessment in biomedical research: the GOT-IT recommendations

Nature Reviews Drug Discovery
Volume 20 Issue 1, January 2021
https://www.nature.com/nrd/volumes/20/issues/1

 

Perspective | 16 November 2020
Improving target assessment in biomedical research: the GOT-IT recommendations
Academic research has a key role in identifying new drug targets, but to lead to new drugs this research must progress to testing drug candidates in clinical trials, which are typically conducted by industry. This Perspective presents a framework to support academic scientists and funders in prioritizing target assessment activities and in defining a critical path to reach scientific goals as well as goals related to licensing, partnering with industry or initiating clinical trials.
Christoph H. Emmerich, Lorena Martinez Gamboa[…] & Michael J. Parnham