Randomized Trial of a Vaccine Regimen to Prevent Chronic HCV Infection

New England Journal of Medicine
February 11, 2021 Vol. 384 No. 6
http://www.nejm.org/toc/nejm/medical-journal

 

Original Article
Randomized Trial of a Vaccine Regimen to Prevent Chronic HCV Infection
Kimberly Page, Ph.D., M.P.H., et al
…In this trial, the HCV vaccine regimen did not cause serious adverse events, produced HCV-specific T-cell responses, and lowered the peak HCV RNA level, but it did not prevent chronic HCV infection. (Funded by the National Institute of Allergy and Infectious Diseases; ClinicalTrials.gov number, NCT01436357. opens in new tab.)