Nature Reviews Genetics
Volume 22 Issue 3, March 2021
Review Article | 04 December 2020
Host genetics and infectious disease: new tools, insights and translational opportunities
Infectious diseases are an ever-present global threat. In this Review, Kwok, Mentzer and Knight discuss our latest understanding of how human genetics influence susceptibility to disease. Furthermore, they discuss emerging progress in the interplay between host and pathogen genetics, molecular responses to infection and vaccination, and opportunities to bring these aspects together for rapid responses to emerging diseases such as COVID-19.
Andrew J. Kwok, Alex Mentzer & Julian C. Knight