COVID-19 vaccines: modes of immune activation and future challenges

Nature Reviews Immunology
Volume 21 Issue 4, April 2021
https://www.nature.com/nri/volumes/21/issues/4

 

Comment | 05 March 2021
COVID-19 vaccines: modes of immune activation and future challenges
This Comment outlines how the recently licensed vaccines for COVID-19 activate innate immune mechanisms to promote immune memory to SARS-CoV-2. The authors also consider future challenges that could limit vaccine efficacy.
John R. Teijaro & Donna L. Farber