Leveraging Open Science to Accelerate Research

New England Journal of Medicine
April 29, 2021 Vol. 384 No. 17


Leveraging Open Science to Accelerate Research
Kushal T. Kadakia, M.Sc., Adam L. Beckman, B.S., Joseph S. Ross, M.D., M.H.S., and Harlan M. Krumholz, M.D.
… The idea of embracing open science represents a vision for research conduct that promotes standard processes for sharing protocols and registering studies, reporting and disseminating results, and sharing data, biospecimens, and code. The advancement of science — an intrinsically iterative process — is contingent on reporting practices that enable data to be findable, accessible, interoperable, and reusable to permit independent scrutiny, replication, and follow-on investigations. Realizing the value of research and fostering trust in science requires study information to be readily available to the public and the scientific community, including in open-access journals and on preprint platforms. Over the past 20 years, policymakers and investigators have promoted open science to counteract clinical researchers’ tendency to sequester data. Such efforts have included the recent release of NIH data-sharing guidelines and public–private partnerships for data sharing, such as the Yale University Open Data Access Project (which two of us help to lead). The urgency associated with the pandemic has created an imperative to accelerate the adoption of open science…