Nature Reviews Drug Discovery
Volume 20 Issue 5, May 2021
Review Article | 01 March 2021
Strategies for delivering therapeutics across the blood–brain barrier
The blood–brain barrier is a perennial challenge for the delivery of therapeutics to the central nervous system. In their Review, Terstappen and colleagues discuss non-invasive approaches to brain delivery, particularly for biopharmaceuticals, some of which are now in clinical testing.
Georg C. Terstappen, Axel H. Meyer, Wandong Zhang