Incorporating Adult Evidence Into Pediatric Research and PracticeBayesian Designs to Expedite Obtaining Child-Specific Evidence

JAMA
May 11, 2021, Vol 325, No. 18, Pages 1813-1912
https://jamanetwork.com/journals/jama/currentissue

 

Viewpoint
Incorporating Adult Evidence Into Pediatric Research and PracticeBayesian Designs to Expedite Obtaining Child-Specific Evidence
Srinivas Murthy, MD, CM, MHSc; Patricia Fontela, MD; Scott Berry, PhD
free access
JAMA. 2021;325(19):1937-1938. doi:10.1001/jama.2020.25007
This Viewpoint proposes ways to use bayesian methods to integrate evidence from adult clinical trials into the conduct, interpretation, and application of pediatric trials to generate scientifically robust and clinically actionable data for the care of children at a pace comparable with that for adults