Nature Reviews Drug Discovery
Volume 20 Issue 6, June 2021
Review Article | 06 April 2021
Emerging concepts in the science of vaccine adjuvants
This Review discusses how recent advances in understanding the activation of the innate immune system are shedding light on the immunological mechanisms of action of adjuvants and highlights how systems-based approaches are beginning to revitalize adjuvant design and development.
Bali Pulendran, Prabhu S. Arunachalam, Derek T. O’Hagan