Volume 594 Issue 7864, 24 June 2021
Article | 10 May 2021
Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses
Immunization of macaques with nanoparticle-conjugated receptor-binding domain of SARS-CoV-2 adjuvanted with 3M-052 and alum results in cross-neutralizing antibodies against bat coronaviruses, SARS-CoV and SARS-CoV-2 variants, and may provide a platform for developing pan-coronavirus vaccines.
Kevin O. Saunders, Esther Lee, Barton F. Haynes