Nature Reviews Immunology
Volume 21 Issue 9, September 2021
Comment | 16 July 2021
SARS-CoV-2 and HIV-1 — a tale of two vaccines
It took roughly 1 year for a COVID-19 vaccine to become available, yet, four decades after the first patient with HIV was described, we do not yet have a vaccine for HIV. Here, Barton Haynes examines the biological reasons why vaccine development for HIV is so exceptionally challenging.
Barton F. Haynes