Individualized therapy trials: navigating patient care, research goals and ethics

Nature Medicine
Volume 27 Issue 10, October 2021
https://www.nature.com/nm/volumes/27/issues/10

 

Perspective | 12 October 2021
Individualized therapy trials: navigating patient care, research goals and ethics
In this Perspective, the authors discuss the ethical challenges of individualized therapy (also called n-of-1) trials and argue that, although customized for the patient, these constitute ‘research’ nonetheless.
Patrick Bodilly Kane, Merlin Bittlinger, Jonathan Kimmelman