Transition to endemicity: Understanding COVID-19

Oct 12, 2021 Volume 54 Issue 10 p2169-2436


Transition to endemicity: Understanding COVID-19
Rustom Antia, M. Elizabeth Halloran
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated disease, coronavirus disease 2019 (COVID-19), has caused a devastating pandemic worldwide. Here, we explain basic concepts underlying the transition from an epidemic to an endemic state, where a pathogen is stably maintained in a population. We discuss how the number of infections and the severity of disease change in the transition from the epidemic to the endemic phase and consider the implications of this transition in the context of COVID-19.