Nature Reviews Drug Discovery
Volume 20 Issue 11, November 2021
Review Article | 25 August 2021
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
The COVID-19 pandemic has established mRNA vaccines as a rapid, effective and safe approach for the protection of individuals from infectious disease. Here, Whitehead and colleagues review the principles of mRNA vaccine design, synthesis and delivery, assessing recent progress and key issues in the development of mRNA vaccines for a range of infectious diseases.
Namit Chaudhary, Drew Weissman, Kathryn A. Whitehead