A supply gap of more than 1 billion autodisable syringes could impact COVID-19 immunization efforts in 100 countries

A supply gap of more than 1 billion autodisable syringes could impact COVID-19 immunization efforts in 100 countries
Global convening of syringe manufacturers and multilateral organizations held to help bolster supply.

Seattle, Washington, November 17, 2021—New PATH modeling estimates a global market supply gap of 1.2 billion autodisable (AD) syringe safe-injection devices for COVID-19 vaccine delivery. This supply gap risks becoming a bottleneck that could threaten the timely delivery of vaccines in half of the countries on Earth.

On November 11, PATH and the United Nations Children’s Fund (UNICEF) held a Global COVID-19 Vaccine Syringe Industry Convening bringing together more than two dozen of the world’s leading syringe manufacturers and multilateral organizations to facilitate increased transparency around the AD syringe market to help bolster supply for COVID-19 vaccines as well as routine immunization. Manufacturers confirmed critical global AD syringe supply challenges from the end of 2021 through mid-2022, despite tripling their production and efforts by multilateral organizations to secure additional AD syringes for low- and middle-income countries that need them.

The projected spike in demand for syringes for COVID-19 vaccines, estimated to total more than 4 billion from the end of 2021 to mid-2022, is due to the anticipated surge in COVID-19 vaccine dose deliveries to countries coming through COVAX, large donations from governments, and bilateral deals. Based on the global supply and demand data, the PATH modeling estimates a global gap of 1.2 billion AD syringes.

Risks to syringe supply such as country export restrictions, shipping delays, new manufacturing lines failing to receive World Health Organization (WHO) prequalification, or delays in completing planned manufacturing expansions could widen the cumulative gap to more than 2 billion during this period. Booster doses could create additional demand pressures on the market.

“Our gap analysis is designed to demystify the market and spur efforts in both public and private sectors to prioritize equitable access to COVID-19 vaccines and syringes in every country as well as to safeguard syringe supplies for essential vaccines for children,” said Tara Herrick, Senior Market Analytics Officer, PATH. “While these future projections are not set in stone, collectively our actions could help curtail the size of future gaps to help reach the global COVID-19 vaccination target of 70 percent by 2022.”

Immunization is done exclusively with AD syringes in nearly 70 countries, and 30 countries use them for some immunizations. Since 1999, the WHO, UNICEF, and the United Nations Population Fund have recommended exclusive use of AD syringes globally for immunization as they “present the lowest risk of person-to-person transmission of blood-borne pathogens such as hepatitis B or HIV” because AD syringe needles cannot be removed or reused…