Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Nature Medicine
Volume 27 Issue 11, November 2021
https://www.nature.com/nm/volumes/27/issues/11

 

Article | 09 September 2021 | Open Access
Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial
A randomized trial in patients hospitalized with COVID-19 showed no benefit and potentially increased harm associated with the use of convalescent plasma, with subgroup analyses suggesting that the antibody profile in donor plasma is critical in determining clinical outcomes.
Philippe Bégin, Jeannie Callum, Donald M. Arnold