Exome sequencing and analysis of 454,787 UK Biobank participants

Nature
Volume 599 Issue 7886, 25 November 2021
https://www.nature.com/nature/volumes/599/issues/7886

 

Article | 18 October 2021 | Open Access
Exome sequencing and analysis of 454,787 UK Biobank participants
Whole-exome sequencing analysis of 454,787 individuals in the UK Biobank is used to examine the association of protein-coding variants with nearly 4,000 health-related traits, identifying 564 distinct genes with significant trait associations.
Joshua D. Backman, Alexander H. Li, Manuel A. R. Ferreira