Engineering living therapeutics with synthetic biology

Nature Reviews Drug Discovery
Volume 20 Issue 12, December 2021
https://www.nature.com/nrd/volumes/20/issues/12

 

Review Article | 06 October 2021
Engineering living therapeutics with synthetic biology
The design of cell-based therapeutics with synthetic biology is a rapidly growing strategy in medicine for the development of effective treatments for a variety of diseases. This article discusses advances in synthetic biology approaches to programme living cells with therapeutic functions as well as challenges for their development.
Andres Cubillos-Ruiz, Tingxi Guo, Jose M. Lora