Nature Reviews Genetics
Volume 22 Issue 12, December 2021
Review Article | 17 September 2021
The biological and clinical significance of emerging SARS-CoV-2 variants
In this Review, the authors describe our latest understanding of the emergence and properties of SARS-CoV-2 genetic variants, particularly those designated as WHO (World Health Organization) ‘variants of concern’. They focus on the consequences of these variants for antibody-mediated virus neutralization, with important implications for reinfection risk and for vaccine effectiveness.
Kaiming Tao, Philip L. Tzou, Robert W. Shafer