Pre-Print Servers

Pre-Print Servers


Gates Open Research
[Accessed 11 Dec 2021]

Research Article metrics AWAITING PEER REVIEW
Do differentiated service delivery models for HIV treatment in sub-Saharan Africa save money? Synthesis of evidence from field studies conducted in sub-Saharan Africa in 2017-2019 [version 1; peer review: awaiting peer review]
Sydney Rosen, Brooke Nichols, Teresa Guthrie, Mariet Benade, Salome Kuchukhidze, Lawrence Long
Peer Reviewers Invited
Funder – NIH
PUBLISHED 08 Dec 2021


medRxiv is a free online archive and distribution server for complete but unpublished manuscripts (preprints) in the medical, clinical, and related health sciences. Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information. medRxiv is for the distribution of preprints – complete but unpublished manuscripts – that describe human health research conducted, analyzed, and interpreted according to scientific principles…
[Accessed 11 Dec 2021]
Selected Content
SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection
Sandile Cele, Laurelle Jackson, Khadija Khan, David S Khoury, Thandeka Moyo-Gwete, Houriiyah Tegally, Cathrine Scheepers, Daniel Amoako, Farina Karim, Mallory Bernstein, Gila Lustig, Derseree Archary, Muneerah Smith, Yashica Ganga, Zesuliwe Jule, Kajal Reedoy, James Emmanuel San, Shi-Hsia Hwa, Jennifer Giandhari, Jonathan Blackburn, Bernadett I Gosnell, Salim Abdool Karim, Willem Hanekom, NGS-SA, COMMIT-KZN Team, Anne von Gottberg, Jinal Bhiman, Richard Lessells, Mahomed-Yunus S Moosa, Miles Philip Davenport, Tulio de Oliveira, Penny L. Moore, Alex Sigal
medRxiv 2021.12.08.21267417; doi:

The prevalence of adaptive immunity to COVID-19 and reinfection after recovery, a comprehensive systematic review and meta-analysis
Tawanda Chivese, Joshua Matizanadzo, Omran Musa, George Hindy, Luis Furuya-Kanamori, Nazmul Islam, Rafal Al-Shebly, Rana Shalaby, Mohammad Habibullah, Talal Al-Marwani, Rizeq F Hourani, Ahmed D Nawaz, Mohammad Haider, Mohamed M Emara, Farhan Cyprian, Suhail A. R. Doi
medRxiv 2021.09.03.21263103; doi:

Screening and vaccination against COVID-19 to minimize school closure
Elisabetta Colosi, Giulia Bassignana, Diego A Contreras, Canelle Poirier, Pierre-Yves Boëlle, Simon Cauchemez, Yazdan Yazdanpanah, Bruno Lina, Arnaud Fontanet, Alain Barrat, Vittoria Colizza
medRxiv 2021.08.15.21261243; doi:

Estimates of reduced vaccine effectiveness against hospitalization, infection, transmission and symptomatic disease of a new SARS-CoV-2 variant, Omicron (B.1.1.529), using neutralizing antibody titers
Billy J Gardner, A. Marm Kilpatrick
medRxiv 2021.12.10.21267594; doi:

Knowledge, attitudes, and practices (KAP) towards COVID-19: A quick online cross-sectional survey among Tanzanian residents.
sima rugarabamu, Aisha Byanaku, Mariam Ibrahim
medRxiv 2020.04.26.20080820; doi:

Surveillance of COVID-19 vaccine effectiveness – a real-time case-control study in southern Sweden
Jonas Björk, Carl Bonander, Mahnaz Moghaddassi, Magnus Rasmussen, Ulf Malmqvist, Fredrik Kahn, Malin Inghammar
medRxiv 2021.12.09.21267515; doi:

Trust in the research community predicts intent to comply with COVID-19 prevention measures: An analysis of a large-scale international survey dataset
Hyemin Han
medRxiv 2021.12.08.21267486; doi:

Vaccine hesitancy for COVID-19 explored in a phenomic study of 259 socio-cognitive-behavioural measures in the UK-REACH study of 12,431 UK healthcare workers
I Chris McManus, Katherine Woolf, Christopher A Martin, Laura B Nellums, Anna L Guyatt, Carl Melbourne, Luke Bryant, Amit Gupta, Catherine John, Martin D Tobin, Sue Carr, Sandra Simpson, Bindu Gregary, Avinash Aujayeb, Stephen Zingwe, Rubina Reza, Laura J Gray, Kamlesh Khunti, Manish Pareek
medRxiv 2021.12.08.21267421; doi:

Vaccine hesitancy for COVID-19 explored in a phenomic study of 259 socio-cognitive-behavioural measures in the UK-REACH study of 12,431 UK healthcare workers
I Chris McManus, Katherine Woolf, Christopher A Martin, Laura B Nellums, Anna L Guyatt, Carl Melbourne, Luke Bryant, Amit Gupta, Catherine John, Martin D Tobin, Sue Carr, Sandra Simpson, Bindu Gregary, Avinash Aujayeb, Stephen Zingwe, Rubina Reza, Laura J Gray, Kamlesh Khunti, Manish Pareek
medRxiv 2021.12.08.21267421; doi:

Global disparities in SARS-CoV-2 genomic surveillance
Anderson F. Brito, Elizaveta Semenova, Gytis Dudas, Gabriel W. Hassler, Chaney C. Kalinich, Moritz U.G. Kraemer, Joses Ho, Houriiyah Tegally, George Githinji, Charles N. Agoti, Lucy E. Matkin, Charles Whittaker, Danish Covid-19 Genome Consortium, COVID-19 Impact Project, Network for Genomic Surveillance in South Africa (NGS-SA), GISAID core curation team, Benjamin P Howden, Vitali Sintchenko, Neta S. Zuckerman, Orna Mor, Heather M Blankenship, Tulio de Oliveira, Raymond T. P. Lin, Marilda Mendonça Siqueira, Paola Cristina Resende, Ana Tereza R. Vasconcelos, Fernando R. Spilki, Renato Santana Aguiar, Ivailo Alexiev, Ivan N. Ivanov, Ivva Philipova, Christine V. F. Carrington, Nikita S. D. Sahadeo, Céline Gurry, Sebastian Maurer-Stroh, Dhamari Naidoo, Karin J von Eije, Mark D. Perkins, Maria van Kerkhove, Sarah C. Hill, Ester C. Sabino, Oliver G. Pybus, Christopher Dye, Samir Bhatt, Seth Flaxman, Marc A. Suchard, Nathan D. Grubaugh, Guy Baele, Nuno R. Faria
medRxiv 2021.08.21.21262393; doi:
Genomic sequencing provides critical information to track the evolution and spread of SARS-CoV-2, optimize molecular tests, treatments and vaccines, and guide public health responses. To investigate the spatiotemporal heterogeneity in the global SARS-CoV-2 genomic surveillance, we estimated the impact of sequencing intensity and turnaround times (TAT) on variant detection in 167 countries. Most countries submit genomes >21 days after sample collection, and 77% of low and middle income countries sequenced <0.5% of their cases. We found that sequencing at least 0.5% of the cases, with a TAT <21 days, could be a benchmark for SARS-CoV-2 genomic surveillance efforts. Socioeconomic inequalities substantially impact our ability to quickly detect SARS-CoV-2 variants, and undermine the global pandemic preparedness. The challenge of limited vaccine supplies: impact of prior infection on anti-spike IgG antibody trajectories after a single COVID-19 vaccination
Jia Wei, Philippa C. Matthews, Nicole Stoesser, Ian Diamond, Ruth Studley, Emma Rourke, Duncan Cook, John I Bell, John N Newton, Jeremy Farrar, Alison Howarth, Brian D. Marsden, Sarah Hoosdally, E Yvonne Jones, David I Stuart, Derrick W. Crook, Tim E. A. Peto, A. Sarah Walker, David W. Eyre, Koen B. Pouwels, the COVID-19 Infection Survey team
medRxiv 2021.12.08.21267353; doi:

Long COVID Citizen Scientists – Developing a needs-based research agenda by persons affected by Long COVID
Sarah Ziegler, Alessia Raineri, Vasileios Nittas, Natalie Rangelov, Fabian Vollrath, Chantal Britt, Milo A Puhan
medRxiv 2021.12.08.21267181; doi:

COVID-19 Vaccination Mandates and Vaccine Uptake
Alexander Karaivanov, Dongwoo Kim, Shih En Lu, Hitoshi Shigeoka
medRxiv 2021.10.21.21265355; doi:
We evaluate the impact of government mandated proof of vaccination requirements for access to public venues and non-essential businesses on COVID-19 vaccine uptake. We find that the announcement of a mandate is associated with a rapid and significant surge in new vaccinations (more than 60% increase in weekly first doses) using the variation in the timing of these measures across Canadian provinces in a difference-in-differences approach. Time-series analysis for each province and for France, Italy and Germany corroborates this finding, and we estimate cumulative gains of up to 5 percentage points in provincial vaccination rates and 790,000 or more first doses for Canada as a whole as of October 31, 2021 (5 to 13 weeks after the provincial mandate announcements). We also find large vaccination gains in France (3 to 5 mln first doses), Italy (around 6 mln) and Germany (around 3.5 mln) 11 to 16 weeks after the proof of vaccination mandate announcements.

COVID-19 infections post-vaccination by HIV status in the United States
Sally B. Coburn, Elizabeth Humes, Raynell Lang, Cameron Stewart, Brenna C Hogan, Kelly A. Gebo, Sonia Napravnik, Jessie K. Edwards, Lindsay E. Browne, Lesley S. Park, Amy C. Justice, Kirsha Gordon, Michael A. Horberg, Julia M. Certa, Eric Watson, Celeena R Jefferson, Michael Silverberg, Jacek Skarbinski, Wendy A Leyden, Carolyn F. Williams, Keri N. Althoff, for the Corona-Infectious-Virus Epidemiology Team (CIVETs) of the NA-ACCORD of IeDEA
medRxiv 2021.12.02.21267182; doi:

Wellcome Open Research [to 11 Dec 2021]
[Accessed 11 Dec 2021]

Wellcome Open Research provides all Wellcome researchers with a place to rapidly publish any results they think are worth sharing. All articles benefit from rapid publication, transparent peer review and editorial guidance on making all source data openly available.

Research Article metrics
Estimating the number of undetected COVID-19 cases among travellers from mainland China [version 3; peer review: 3 approved]
Sangeeta Bhatia, Natsuko Imai, Gina Cuomo-Dannenburg, Marc Baguelin, Adhiratha Boonyasiri, Anne Cori, Zulma Cucunubá, Ilaria Dorigatti, Rich FitzJohn, Han Fu, Katy Gaythorpe, Azra Ghani, Arran Hamlet, Wes Hinsley, Daniel Laydon, Gemma Nedjati-Gilani, Lucy Okell, Steven Riley, Hayley Thompson, Sabine van Elsland, Erik Volz, Haowei Wang, Yuanrong Wang, Charles Whittaker, Xiaoyue Xi, Christl A. Donnelly, Neil M. Ferguson
Peer Reviewers Jeremy Bingham and Juliet R.C. Pulliam; Sebastian Funk; Hannah E. Clapham
Wellcome Trust
European and Developing Countries Clinical Trials Partnership
National Institute for Health Research
Department for International Development, UK Government
Medical Research Council