Yearly Archives: 2021

Determinants of low uptake of vaccination against influenza, measles, and hepatitis B among healthcare professionals in Greece: a multicenter cross-sectional study

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Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 16, Issue 11, 2020
http://www.tandfonline.com/toc/khvi20/current

 

Article
Determinants of low uptake of vaccination against influenza, measles, and hepatitis B among healthcare professionals in Greece: a multicenter cross-sectional study
Olga Vrachnaki, Eleni Vergadi, Eleni Ioannidou & Emmanouil Galanakis
Pages: 2663-2669
Published online: 13 May 2020

Dengue vaccines: the road to failure or to success?

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Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 16, Issue 11, 2020
http://www.tandfonline.com/toc/khvi20/current

 

article commentary
Dengue vaccines: the road to failure or to success?
Stanley A. Plotkin
Pages: 2677-2679
Published online: 19 May 2020
A licensed vaccine against dengue was shown to enhance disease under some circumstances, even though it protected most vaccinees. We discuss the implication of these results for the future of dengue vaccines.

Meningococcal infections among refugees and immigrants: silent threats of past, present and future

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Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 16, Issue 11, 2020
http://www.tandfonline.com/toc/khvi20/current

 

Review
Meningococcal infections among refugees and immigrants: silent threats of past, present and future
Ener Cagri Dinleyici & Ray Borrow on behalf of Global Meningococcal Initiative
Pages: 2781-2786
Published online: 29 Apr 2020

Review of long term immunogenicity and tolerability of live hepatitis A vaccine

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Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 16, Issue 11, 2020
http://www.tandfonline.com/toc/khvi20/current

 

Review of long term immunogenicity and tolerability of live hepatitis A vaccine
Nitin Shah, MMA Faridi, Monjori Mitra, Ashish Bavdekar, Archana Karadkhele, Gaurav Puppalwar & Rishi Jain
Pages: 2816-2821
Published online: 03 Apr 2020

Pathway towards an ideal and sustainable framework agreement for the public procurement of vaccines in Spain: a multi-criteria decision analysis

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Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 16, Issue 11, 2020
http://www.tandfonline.com/toc/khvi20/current

 

Article
Pathway towards an ideal and sustainable framework agreement for the public procurement of vaccines in Spain: a multi-criteria decision analysis
N. Zozaya González, B. Alcalá Revilla, P. Arrazola Martínez, J. R. Chávarri Bravo, I. Cuesta Esteve, A. J. García Rojas, F. Martinón-Torres, E. Redondo Margüello, A. Rivero Cuadrado, S. Tamames Gómez, J. Villaseca Carmena & A. Hidalgo-Vega
Pages: 2873-2884
Published online: 03 Apr 2020

Mandating COVID-19 Vaccines

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JAMA Network
COVID-19 Update January 2, 2021

 

These articles on COVID-19 were published across the JAMA Network in the last week.
Selected Articles
Opinion
Mandating COVID-19 Vaccines
Lawrence O. Gostin, JD; Daniel A. Salmon, MPH, PhD; Heidi J. Larson, PhD
…From EUAs to BLA Approvals
Mandating COVID-19 vaccines under an EUA is legally and ethically problematic. The act authorizing the FDA to issue EUAs requires the secretary of the Department of Health and Human Services (HHS) to specify whether individuals may refuse the vaccine and the consequences for refusal. Vaccine mandates are unjustified because an EUA requires less safety and efficacy data than full Biologics License Application (BLA) approval. Individuals would also likely distrust vaccine mandates under emergency use, viewing it as ongoing medical research.
Should SARS-CoV-2 Vaccines Be Mandatory?
Once SARS-CoV-2 vaccines receive a BLA, policy makers must determine to which, if any, populations mandates should apply. Vaccine mandates could be imposed in multiple sectors, each with their own legal and ethical considerations…

Willingness to Vaccinate Children against Influenza after the Coronavirus Disease 2019 Pandemic

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Journal of Pediatrics
January 2021 Volume 228 p1-326
http://www.jpeds.com/current

 

Original Articles
Willingness to Vaccinate Children against Influenza after the Coronavirus Disease 2019 Pandemic
Ran D. Goldman, Sophie McGregor, Shashidhar R. Marneni,…Samina Ali, Julie C. Brown
andfor the International COVID-19 Parental Attitude Study (COVIPAS) Group
Published online: August 06, 2020
p87-93.e2

Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in children and infants: two clinical trials

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The Lancet
Jan 02, 2021 Volume 397 Number 10268 p1-70, e1
https://www.thelancet.com/journals/lancet/issue/current

 

Articles
Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in children and infants: two clinical trials
Xavier Sáez-Llorens, et al
Open Access

Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in healthy adults: two clinical trials

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The Lancet
Jan 02, 2021 Volume 397 Number 10268 p1-70, e1
https://www.thelancet.com/journals/lancet/issue/current

 

Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in healthy adults: two clinical trials
Ilse De Coster, et al
Open Access

Development and dissemination of infectious disease dynamic transmission models during the COVID-19 pandemic: what can we learn from other pathogens and how can we move forward?

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Lancet Digital Health
Jan 2021 Volume 3 Number 1 e1-e66
https://www.thelancet.com/journals/landig/issue/current

 

Review
Development and dissemination of infectious disease dynamic transmission models during the COVID-19 pandemic: what can we learn from other pathogens and how can we move forward?
Alexander D Becker, yra H Grantz, Sonia T Hegde, Sophie Bérubé, Derek A T Cummings, Amy Wesolowski

Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBIBP-CorV: a randomised, double-blind, placebo-controlled, phase 1/2 trial

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Lancet Infectious Diseases
Jan 2021 Volume 21 Number 1 p1-148, e1-e16
https://www.thelancet.com/journals/laninf/issue/current

 

Articles
Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBIBP-CorV: a randomised, double-blind, placebo-controlled, phase 1/2 trial
Shengli Xia, et al

Indirect effects of the COVID-19 pandemic on malaria intervention coverage, morbidity, and mortality in Africa: a geospatial modelling analysis

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Lancet Infectious Diseases
Jan 2021 Volume 21 Number 1 p1-148, e1-e16
https://www.thelancet.com/journals/laninf/issue/current

 

Indirect effects of the COVID-19 pandemic on malaria intervention coverage, morbidity, and mortality in Africa: a geospatial modelling analysis
Daniel J Weiss, et al
Open Access

Epidemiology of varicella among immigrants and non-immigrants in Quebec, Canada, before and after the introduction of childhood varicella vaccination: a retrospective cohort study

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Lancet Infectious Diseases
Jan 2021 Volume 21 Number 1 p1-148, e1-e16
https://www.thelancet.com/journals/laninf/issue/current

 

Epidemiology of varicella among immigrants and non-immigrants in Quebec, Canada, before and after the introduction of childhood varicella vaccination: a retrospective cohort study
Christina Greenaway, et al

Dynamic changes in paediatric invasive pneumococcal disease after sequential switches of conjugate vaccine in Belgium: a national retrospective observational study

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Lancet Infectious Diseases
Jan 2021 Volume 21 Number 1 p1-148, e1-e16
https://www.thelancet.com/journals/laninf/issue/current

Dynamic changes in paediatric invasive pneumococcal disease after sequential switches of conjugate vaccine in Belgium: a national retrospective observational study
Stefanie Desmet, et al

Invasive pneumococcal disease incidence in children and adults in France during the pneumococcal conjugate vaccine era: an interrupted time-series analysis of data from a 17-year national prospective surveillance study

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Lancet Infectious Diseases
Jan 2021 Volume 21 Number 1 p1-148, e1-e16
https://www.thelancet.com/journals/laninf/issue/current

 

Invasive pneumococcal disease incidence in children and adults in France during the pneumococcal conjugate vaccine era: an interrupted time-series analysis of data from a 17-year national prospective surveillance study
Naïm Ouldali, et al

Ethical and Legal Implications of Remote Monitoring of Medical Devices

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The Milbank Quarterly
A Multidisciplinary Journal of Population Health and Health Policy

Ethical and Legal Implications of Remote Monitoring of Medical Devices
I. GLENN COHEN, SARA GERKE, DANIEL B. KRAMER

 

Pages: 1257-1289
First Published: 20 October 2020
Abstract
Policy Points
:: Millions of life‐sustaining implantable devices collect and relay massive amounts of digital health data, increasingly by using user‐downloaded smartphone applications to facilitate data relay to clinicians via manufacturer servers.
:: Our analysis of health privacy laws indicates that most US patients may have little access to their own digital health data in the United States under the Health Insurance Portability and Accountability Act Privacy Rule, whereas the EU General Data Protection Regulation and the California Consumer Privacy Act grant greater access to device‐collected data.
:: Our normative analysis argues for consistently granting patients access to the raw data collected by their implantable devices.

A Commons for a Supply Chain in the Post‐COVID‐19 Era: The Case for a Reformed Strategic National Stockpile

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The Milbank Quarterly
A Multidisciplinary Journal of Population Health and Health Policy

 

Volume 98, Issue 4 Pages: 1021-1341, E1-E12 December 2020
https://onlinelibrary.wiley.com/toc/14680009/current
Original Scholarship
Free Access
A Commons for a Supply Chain in the Post‐COVID‐19 Era: The Case for a Reformed Strategic National Stockpile
ROBERT HANDFIELD, DANIEL JOSEPH FINKENSTADT, EUGENE S. SCHNELLER, A. BLANTON GODFREY
PETER GUINTO
Pages: 1058-1090
First Published: 02 November 2020

Genetics meets proteomics: perspectives for large population-based studies

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Nature Reviews Genetics
Volume 22 Issue 1, January 2021
https://www.nature.com/nrg/volumes/22/issues/1

 

Review Article | 28 August 2020
Genetics meets proteomics: perspectives for large population-based studies
In this Review, Suhre, McCarthy and Schwenk describe how combining genetics with plasma proteomics is providing notable insights into human disease. As changes in the circulating proteome are often an intermediate molecular readout between a genetic variant and its organismal effect, proteomics can enable a deeper understanding of disease mechanisms, clinical biomarkers and therapeutic opportunities.
Karsten Suhre , Mark I. McCarthy  & Jochen M. Schwenk

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

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New England Journal of Medicine
December 31, 2020 Vol. 383 No. 27
http://www.nejm.org/toc/nejm/medical-journal

 

Original Articles
Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
Fernando P. Polack, M.D., et al for the C4591001 Clinical Trial Group
Conclusions
A two-dose regimen of BNT162b2 conferred 95% protection against Covid-19 in persons 16 years of age or older. Safety over a median of 2 months was similar to that of other viral vaccines. (Funded by BioNTech and Pfizer; ClinicalTrials.gov number, NCT04368728)

Three-Year Follow-up of 2-Dose Versus 3-Dose HPV Vaccine

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Pediatrics
Vol. 147, Issue 1 1 Jan 2021
https://pediatrics.aappublications.org/

 

Three-Year Follow-up of 2-Dose Versus 3-Dose HPV Vaccine
Jacob Bornstein, Surita Roux, Lone Kjeld Petersen, Li-Min Huang, Simon R. Dobson, Punnee Pitisuttithum, Javier Diez-Domingo, Andrea Schilling, Hany Ariffin, Richard Tytus, Richard Rupp, Shelly Senders, Eli Engel, Daron Ferris, Yae-Jean Kim, Young Tae Kim, Zafer Kurugol, Oliver Bautista, Katrina M. Nolan, Sandhya Sankaranarayanan, Alfred Saah, Alain Luxembourg
Pediatrics, Jan 2021, 147 (1) e20194035

Comparative efficacy and safety of pharmacological interventions for the treatment of COVID-19: A systematic review and network meta-analysis

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PLoS Medicine
http://www.plosmedicine.org/

 

Research Article |
Comparative efficacy and safety of pharmacological interventions for the treatment of COVID-19: A systematic review and network meta-analysis
Min Seo Kim, Min Ho An, Won Jun Kim, Tae-Ho Hwang
published 30 Dec 2020 PLOS Medicine
https://doi.org/10.1371/journal.pmed.1003501

Parents’ and guardians’ views and experiences of accessing routine childhood vaccinations during the coronavirus (COVID-19) pandemic: A mixed methods study in England

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PLoS One
http://www.plosone.org/
[Accessed 2 Jan 2021]

 

Parents’ and guardians’ views and experiences of accessing routine childhood vaccinations during the coronavirus (COVID-19) pandemic: A mixed methods study in England
Sadie Bell, Richard Clarke, Pauline Paterson, Sandra Mounier-Jack
Research Article | published 28 Dec 2020 PLOS ONE
https://doi.org/10.1371/journal.pone.0244049

Science’s irrational origins

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Science
01 January 2021 Vol 371, Issue 6524
http://www.sciencemag.org/current.dtl

 

Books et al.
Science’s irrational origins
By Itai Yanai, Martin J. Lercher
Science01 Jan 2021 : 37 Restricted Access
Disputes in modern science are settled with empiricism alone, an approach early scholars would have questioned
Summary
What is the scientific method, and what makes it the most efficient approach for generating insight? In The Knowledge Machine, Michael Strevens argues that to answer this question, we must acknowledge the role played by the undisciplined and emotional nature of the humans who carry it out. The book takes readers on a whirlwind tour through the history of science, rendering Arthur Eddington, Louis Pasteur, G. G. Simpson, Lord Kelvin, and many others as “warm-blooded organisms, whose enthusiasms, hopes, and fears mold their thinking far below the threshold of awareness.”