The RTS,S vaccine—a chance to regain the upper hand against malaria?

Cell
Mar 03, 2022 Volume 185 Issue 5 p747-938
https://www.cell.com/cell/current

 

Benchmarks
The RTS,S vaccine—a chance to regain the upper hand against malaria?
Photini Sinnis, David A. Fidock
Malaria is estimated by the World Health Organization (WHO) to have killed 627,000 individuals worldwide in 2020, with nearly 80% of deaths in African children younger than five. The recent WHO approval of the RTS,S/AS01 vaccine, which targets Plasmodium falciparum pre-erythrocytic stages, provides hope that its use combined with other interventions can help reverse the current malaria resurgence.