No Consistent Evidence of Decreased Exposure to Varicella-Zoster Virus Among Older Adults in Countries with Universal Varicella Vaccination

Journal of Infectious Diseases
Volume 225, Issue 3, 1 February 2022
https://academic.oup.com/jid/issue/225/3

 

VACCINES
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No Consistent Evidence of Decreased Exposure to Varicella-Zoster Virus Among Older Adults in Countries with Universal Varicella Vaccination
Stephane Carryn, Brigitte Cheuvart, Michael Povey, Alemnew F Dagnew, Rafael Harpaz
The Journal of Infectious Diseases, Volume 225, Issue 3, 1 February 2022, Pages 413–421, https://doi.org/10.1093/infdis/jiab500
By repurposing humoral and cell-mediated immunogenicity data from a large multinational trial enrolling adults aged ≥50 years, we found no consistent evidence of differences in varicella-zoster virus exposure between countries with widely circulating varicella versus countries with universal vaccination.