Volume 604 Issue 7907, 28 April 2022
Article | 07 March 2022 | Open Access
SARS-CoV-2 is associated with changes in brain structure in UK Biobank
Gwenaëlle Douaud, Soojin Lee, Stephen M. Smith
After infection with SARS-CoV-2, individuals show a greater reduction in grey matter thickness and tissue contrast in the orbitofrontal cortex and parahippocampal gyrus; greater changes in markers of tissue damage in regions that are functionally connected to the primary olfactory cortex; and a greater reduction in global brain size.