Reappraising the Value of HIV-1 Vaccine Correlates of Protection Analyses

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Journal of Virology
Volume 96 • Number 8 • April 2022
http://jvi.asm.org/content/current

 

Virology Minireview 06 April 2022
Reappraising the Value of HIV-1 Vaccine Correlates of Protection Analyses
P. J. Klasse, John P. Moore
https://doi.org/10.1128/jvi.00034-22
With the much-debated exception of the modestly reduced acquisition reported for the RV144 efficacy trial, HIV-1 vaccines have not protected humans against infection, and a vaccine of similar design to that tested in RV144 was not protective in a later …