Author Archives: davidrcurry

Journal Watch

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Journal Watch
Vaccines and Global Health: The Week in Review continues its weekly scanning of key peer-reviewed journals to identify and cite articles, commentary and editorials, books reviews and other content supporting our focu-s on vaccine ethics and policy. Journal Watch is not intended to be exhaustive, but indicative of themes and issues the Center is actively tracking. We selectively provide full text of some editorial and comment articles that are specifically relevant to our work. Successful access to some of the links provided may require subscription or other access arrangement unique to the publisher.
If you would like to suggest other journal titles to include in this service, please contact David Curry at: david.r.curry@centerforvaccineethicsandpolicy.org

Ending the HIV Epidemic

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AMA Journal of Ethics
Volume 23, Number 5: E371-433 May 2021
https://journalofethics.ama-assn.org/issue/ending-hiv-epidemic

 

Ending the HIV Epidemic
A human immunodeficiency virus (HIV) epidemic began in the United States in the 1970s. “Ending the HIV Epidemic: A Plan for America” was launched in October 2019 by the US Department of Health and Human Services, with the goal of stopping the spread of HIV by 2030. Accomplishing this goal demands not only expanding existing programs, but recognizing and responding to clinically, ethically, socially, and culturally relevant features of contemporary patients’ experiences of stigma, oppression, and living with HIV. This issue considers ethical and clinical complexities patients and clinicians encounter in HIV care today.

Contact Tracing and the COVID-19 Response in Africa: Best Practices, Key Challenges, and Lessons Learned from Nigeria, Rwanda, South Africa, and Uganda

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American Journal of Tropical Medicine and Hygiene
Volume 104 (2021): Issue 4 (Apr 2021)
https://www.ajtmh.org/view/journals/tpmd/104/4/tpmd.104.issue-4.xml

 

Articles Open access
Contact Tracing and the COVID-19 Response in Africa: Best Practices, Key Challenges, and Lessons Learned from Nigeria, Rwanda, South Africa, and Uganda
Jean B. Nachega, Rhoda Atteh, Chikwe Ihekweazu, Nadia A. Sam-Agudu, Prisca Adejumo, Sabin Nsanzimana, Edson Rwagasore, Jeanine Condo, Masudah Paleker, Hassan Mahomed, Fatima Suleman, Alex Riolexus Ario, Elsie Kiguli-Malwadde, Francis G. Omaswa, Nelson K. Sewankambo, Cecile Viboud, Michael J. A. Reid, Alimuddin Zumla, and Peter H. Kilmarx
DOI: https://doi.org/10.4269/ajtmh.21-0033

Refugee Settlements and Cholera Risks in Uganda, 2016–2019

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American Journal of Tropical Medicine and Hygiene
Volume 104 (2021): Issue 4 (Apr 2021)
https://www.ajtmh.org/view/journals/tpmd/104/4/tpmd.104.issue-4.xml

 

Refugee Settlements and Cholera Risks in Uganda, 2016–2019
Godfrey Bwire, Christopher Garimoi Orach, Freda Loy Aceng, Sam Emmanuel Arianitwe, David Matseketse, Edson Tumusherure, Issa Makumbi, Allan Muruta, Rebecca D. Merrill, Amanda Debes, Mohammad Ali, and David A. Sack
DOI: https://doi.org/10.4269/ajtmh.20-0741

Home Administration of CVD 103-HgR: A Live Attenuated Oral Cholera Vaccine

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American Journal of Tropical Medicine and Hygiene
Volume 104 (2021): Issue 4 (Apr 2021)
https://www.ajtmh.org/view/journals/tpmd/104/4/tpmd.104.issue-4.xml

 

Home Administration of CVD 103-HgR: A Live Attenuated Oral Cholera Vaccine
R. Paul Duffin, Michael Delbuono, Lawrence Chew, James Johnstone, Volker Niedan, Pascal Schwarz, Paul Shabram, and Amish A. Patel
DOI: https://doi.org/10.4269/ajtmh.20-1223

A Double-Blind, Randomized, Placebo-Controlled Phase 1 Study of Ad26.ZIKV.001, an Ad26-Vectored Anti–Zika Virus Vaccine

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Annals of Internal Medicine
May 2021 Volume 174, Issue 5
http://annals.org/aim/issue

 

Original Research
A Double-Blind, Randomized, Placebo-Controlled Phase 1 Study of Ad26.ZIKV.001, an Ad26-Vectored Anti–Zika Virus Vaccine
Nadine C. Salisch, PhD, Kathryn E. Stephenson, MD, MPH, Kristi Williams, BSN, PhD, Freek Cox, PhD, … et al.
Pages:585–594

Major Update: Remdesivir for Adults With COVID-19 – A Living Systematic Review and Meta-analysis for the American College of Physicians Practice Points

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Annals of Internal Medicine
May 2021 Volume 174, Issue 5
http://annals.org/aim/issue

Major Update: Remdesivir for Adults With COVID-19 – A Living Systematic Review and Meta-analysis for the American College of Physicians Practice Points
FREE

 

Anjum S. Kaka, MD, Roderick MacDonald, MS, Nancy Greer, PhD, Kathryn Vela, MLIS, … et al.

Methodological frontiers in vaccine safety: qualifying available evidence for rare events, use of distributed data networks to monitor vaccine safety issues, and monitoring the safety of pregnancy interventions

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BMJ Global Health
May 2021 – Volume 6 – Suppl 2
https://gh.bmj.com/content/6/Suppl_2

 

Methodological frontiers in vaccine safety: qualifying available evidence for rare events, use of distributed data networks to monitor vaccine safety issues, and monitoring the safety of pregnancy interventions (19 May, 2021)
Caitlin Dodd, Nick Andrews, Helen Petousis-Harris, Miriam Sturkenboom, Saad B Omer, Steven Black

Novel vaccine safety issues and areas that would benefit from further research

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BMJ Global Health
May 2021 – Volume 6 – Suppl 2
https://gh.bmj.com/content/6/Suppl_2

 

Novel vaccine safety issues and areas that would benefit from further research (19 May, 2021)
Daniel A Salmon, Paul Henri Lambert, Hanna M Nohynek, Julianne Gee, Umesh D Parashar, Jacqueline E Tate, Annelies Wilder-Smith, Kenneth Y Hartigan-Go, Peter G Smith, Patrick Louis F Zuber

Knowledge, attitude, and acceptance of healthcare workers and the public regarding the COVID-19 vaccine: a cross-sectional study

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BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 22 May 2021)

 

Knowledge, attitude, and acceptance of healthcare workers and the public regarding the COVID-19 vaccine: a cross-sectional study
This study determined the knowledge, attitudes, and practice regarding COVID-19 and assessed the acceptance of the COVID-19 vaccine among healthcare workers and the general population.
Authors: Muhammed Elhadi, Ahmed Alsoufi, Abdulmueti Alhadi, Amel Hmeida, Entisar Alshareea, Mawadda Dokali, Sanabel Abodabos, Omaymah Alsadiq, Mohammed Abdelkabir, Aimen Ashini, Abdulhamid Shaban, Saja Mohammed, Nehal Alghudban, Eman Bureziza, Qasi Najah, Khawla Abdulrahman…
Citation: BMC Public Health 2021 21:955
Content type: Research
Published on: 20 May 2021

Primary care: Building capacity in evidence-based medicine in low-income and middle-income countries: problems and potential solutions

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BMJ Evidence-Based Medicine
June 2021 – Volume 26 – 3
https://ebm.bmj.com/content/26/3

 

EBM opinion and debate
Primary care: Building capacity in evidence-based medicine in low-income and middle-income countries: problems and potential solutions (22 November, 2019)
Peter J Gill, Shabana M Ali, Yasmin Elsobky, Raymond C Okechukwu, Tatiane B Ribeiro, Augusto Cesar Soares dos Santos Junior, Daniel Umpierre, Georgia C Richards

Global genomic pathogen surveillance to inform vaccine strategies: a decade-long expedition in pneumococcal genomics

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Genome Medicine
https://genomemedicine.biomedcentral.com/articles
[Accessed 22 May 2021]

 

Global genomic pathogen surveillance to inform vaccine strategies: a decade-long expedition in pneumococcal genomics
Vaccines are powerful agents in infectious disease prevention but often designed to protect against some strains that are most likely to spread and cause diseases. Most vaccines do not succeed in eradicating t…
Authors: Stephen D. Bentley and Stephanie W. Lo
Citation: Genome Medicine 2021 13:84
Content type: Review
Published on: 17 May 2021

COVID-19 and future pandemics: a global systems approach and relevance to SDGs

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Globalization and Health
http://www.globalizationandhealth.com/
[Accessed 22 May 2021]

 

COVID-19 and future pandemics: a global systems approach and relevance to SDGs
The COVID-19 pandemic is adversely impacting modern human civilization. A global view using a systems science approach is necessary to recognize the close interactions between health of animals, humans and the…
Authors: Tharanga Thoradeniya and Saroj Jayasinghe
Citation: Globalization and Health 2021 17:59
Content type: Debate
Published on: 21 May 2021

How does globalization affect COVID-19 responses?

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Globalization and Health
http://www.globalizationandhealth.com/
[Accessed 22 May 2021]

 

How does globalization affect COVID-19 responses?
The ongoing COVID-19 pandemic has highlighted the vast differences in approaches to the control and containment of coronavirus across the world and has demonstrated the varied success of such approaches in min…
Authors: Steve J. Bickley, Ho Fai Chan, Ahmed Skali, David Stadelmann and Benno Torgler
Citation: Globalization and Health 2021 17:57
Content type: Research
Published on: 20 May 2021

Disability inclusion in humanitarian action

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Humanitarian Exchange Magazine
Number 78, October 2020
https://odihpn.org/magazine/inclusion-of-persons-with-disabilities-in-humanitarian-action-what-now/

 

Disability inclusion in humanitarian action
by HPN October 2020
The theme of this edition of Humanitarian Exchange, co-edited with Sherin Alsheikh Ahmed from Islamic Relief Worldwide, is disability inclusion in humanitarian action. Persons with disabilities are not only disproportionately impacted by conflicts, disasters and other emergencies, but also face barriers to accessing humanitarian assistance. At the same time, global commitments and standards and the IASC Guidelines on the inclusion of persons with disabilities in humanitarian action all emphasise how persons with disabilities are also active agents of change. Disability and age-focused organisations have led on testing and demonstrating how inclusion can be done better. Yet despite this progress, challenges to effective inclusion remain.

As Kirstin Lange notes in the lead article, chief among these challenges is humanitarian agencies’ lack of engagement with organisations of persons with disabilities. Simione Bula, Elizabeth Morgan and Teresa Thomson look at disability inclusion in humanitarian response in the Pacific, and Kathy Al Jubeh and Alradi Abdalla argue for a ‘participation revolution’, building on learning from the gender movement. Tchaurea Fleury and Sulayman AbdulMumuni Ujah outline how the Bridge Article 11 training initiative is encouraging constructive exchange between humanitarian and disability actors. The lack of good, disaggregated data is highlighted by Sarah Collinson; Frances Hill, Jim Cranshaw and Carys Hughes emphasise the need for training resources in local languages and accessible formats; and Sophie Van Eetvelt and colleagues report on a review of the evidence on inclusion of people with disabilities and older people.

Rebecca Molyneux and co-authors analyse the findings of a review of a DFID programme in north-east Nigeria, while Carolin Funke highlights the importance of strategic partnerships between disability-focused organisations, drawing on her research in Cox’s Bazar. Sherin Alsheikh Ahmed describes Islamic Relief Worldwide’s approach to mainstreaming protection and inclusion, while Pauline Thivillier and Valentina Shafina outline IRC’s Client Responsive Programming. The edition ends with reflections by Mirela Turcanu and Yves Ngunzi Kahashi on CAFOD’s SADI approach.

An Asia-Pacific study on healthcare workers’ perceptions of, and willingness to receive, the COVID-19 vaccination

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International Journal of Infectious Diseases
Volume 106 p1-430
https://www.ijidonline.com/current

 

An Asia-Pacific study on healthcare workers’ perceptions of, and willingness to receive, the COVID-19 vaccination
Nicholas W.S. Chew, Clare Cheong, Gwyneth Kong, …Arvind K. Sharma, Roger C. Ho, Vijay K. Sharma
Published online: March 26, 2021
p52-60

SARS-CoV-2–Specific Antibodies in Breast Milk After COVID-19 Vaccination of Breastfeeding Women

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JAMA
May 11, 2021, Vol 325, No. 18, Pages 1813-1912
https://jamanetwork.com/journals/jama/currentissue

 

Research Letter
SARS-CoV-2–Specific Antibodies in Breast Milk After COVID-19 Vaccination of Breastfeeding Women
Sivan Haia Perl, MD; Atara Uzan-Yulzari, MSc; Hodaya Klainer, BSc; et al.
free access has active quiz
JAMA. 2021;325(19):2013-2014. doi:10.1001/jama.2021.5782
This prospective study investigated whether antibodies from SARS-CoV-2 immunization of nursing mothers transferred to infants as a potentially protective effect.

Digital Health Passes in the Age of COVID-19Are “Vaccine Passports” Lawful and Ethical?

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JAMA
May 11, 2021, Vol 325, No. 18, Pages 1813-1912
https://jamanetwork.com/journals/jama/currentissue

 

Viewpoint
Digital Health Passes in the Age of COVID-19Are “Vaccine Passports” Lawful and Ethical?
Lawrence O. Gostin, JD; I. Glenn Cohen, JD; Jana Shaw, MD, MPH
free access
JAMA. 2021;325(19):1933-1934. doi:10.1001/jama.2021.5283
This Viewpoint discusses digital health passes (DHPs) that would grant access to work, entertainment, shopping, and travel with confirmation of COVID-19 immunity, and the scientific, legal, ethical, and equity considerations that must be worked through for DHPs to be considered effective and fair.

Incorporating Adult Evidence Into Pediatric Research and PracticeBayesian Designs to Expedite Obtaining Child-Specific Evidence

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JAMA
May 11, 2021, Vol 325, No. 18, Pages 1813-1912
https://jamanetwork.com/journals/jama/currentissue

 

Viewpoint
Incorporating Adult Evidence Into Pediatric Research and PracticeBayesian Designs to Expedite Obtaining Child-Specific Evidence
Srinivas Murthy, MD, CM, MHSc; Patricia Fontela, MD; Scott Berry, PhD
free access
JAMA. 2021;325(19):1937-1938. doi:10.1001/jama.2020.25007
This Viewpoint proposes ways to use bayesian methods to integrate evidence from adult clinical trials into the conduct, interpretation, and application of pediatric trials to generate scientifically robust and clinically actionable data for the care of children at a pace comparable with that for adults

The value of evidence synthesis

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Nature Human Behaviour
Volume 5 Issue 5, May 2021
https://www.nature.com/nathumbehav/volumes/5/issues/5

 

Editorial | 20 May 2021
The value of evidence synthesis
Science is a cumulative enterprise, and systematic evidence synthesis is invaluable for appraising what is known and what is not known on a specific research question. We strongly encourage the submission of systematic reviews and meta-analyses to Nature Human Behaviour.

Socioeconomic impacts of COVID-19 in low-income countries

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Nature Human Behaviour
Volume 5 Issue 5, May 2021
https://www.nature.com/nathumbehav/volumes/5/issues/5

 

Article | 30 March 2021
Socioeconomic impacts of COVID-19 in low-income countries
Recent phone survey data from Ethiopia, Malawi, Nigeria and Uganda reveals the breadth of the socioeconomic impacts of the COVID-19 pandemic on individuals and households.
Anna Josephson, Talip Kilic, Jeffrey D. Michler

Efficacy of NVX-CoV2373 Covid-19 Vaccine against the B.1.351 Variant Efficacy of NVX-CoV2373 Covid-19 Vaccine against the B.1.351 Variant

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New England Journal of Medicine
May 20, 2021 Vol. 384 No. 20
http://www.nejm.org/toc/nejm/medical-journal

 

Efficacy of NVX-CoV2373 Covid-19 Vaccine against the B.1.351 Variant Efficacy of NVX-CoV2373 Covid-19 Vaccine against the B.1.351 Variant
Vivek Shinde, M.D., M.P.H., et al for the 2019nCoV-501 Study Group*
Conclusions
The NVX-CoV2373 vaccine was efficacious in preventing Covid-19, with higher vaccine efficacy observed among HIV-negative participants. Most infections were caused by the B.1.351 variant. (Funded by Novavax and the Bill and Melinda Gates Foundation; ClinicalTrials.gov number, NCT04533399. opens in new tab.)

Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant

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New England Journal of Medicine
May 20, 2021 Vol. 384 No. 20
http://www.nejm.org/toc/nejm/medical-journal

 

Original Articles
Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant
Shabir A. Madhi, Ph.D., et al for the NGS-SA Group, and the Wits-VIDA COVID Group*
Conclusions
A two-dose regimen of the ChAdOx1 nCoV-19 vaccine did not show protection against mild-to-moderate Covid-19 due to the B.1.351 variant. (Funded by the Bill and Melinda Gates Foundation and others; ClinicalTrials.gov number, NCT04444674. opens in new tab; Pan African Clinical Trials Registry number, PACTR202006922165132. opens in new tab).

Opinion: Compound risks and complex emergencies require new approaches to preparedness

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PNAS – Proceedings of the National Academy of Sciences of the United States of America
May 11, 2021; vol. 118 no. 19
https://www.pnas.org/content/118/19

 

Opinion
Leading scientists discuss current issues
Opinion: Compound risks and complex emergencies require new approaches to preparedness
A. Kruczkiewicz, J. Klopp, J. Fisher, S. Mason, S. McClain, N. M. Sheekh, R. Moss, R. M. Parks, and C. Braneon
PNAS May 11, 2021 118 (19) e2106795118; https://doi.org/10.1073/pnas.2106795118
Increasingly, we face compounding and interrelated environmental, socioeconomic, and political crises. Yet our approaches to these problems are often siloed, fragmented, and inadequate. The current pandemic, for instance, continues to collide with a number of other threats to human life and livelihoods. These include violent conflicts, displacement, insect swarms, droughts, heat waves, and structural inequality in the form of racism and gender discrimination. We believe we are at a critical juncture, faced with a need and responsibility to redesign institutions to be proactive, agile, and socially just when confronted with increasingly likely compound risks…

Global Systemic Risk and Resilience for Novel Coronavirus and COVID-19

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Risk Analysis
Volume 41, Issue 5 Pages: 701-841 May 2021
https://onlinelibrary.wiley.com/toc/15396924/current

 

Special Issue: Global Systemic Risk and Resilience for Novel Coronavirus and COVID‐19: Part 1
Editorial Free Access
Global Systemic Risk and Resilience for Novel Coronavirus and COVID-19
Desheng Dash Wu, Jade Mitchell, James H. Lambert
Pages: 701-704
First Published: 17 May 2021

Impact of reduced human papillomavirus vaccination coverage rates due to COVID-19 in the United States: A model based analysis

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Vaccine
Volume 39, Issue 20 Pages 2731-2810 (12 May 2021)
https://www.sciencedirect.com/journal/vaccine/vol/39/issue/20

 

Short communication Open access
Impact of reduced human papillomavirus vaccination coverage rates due to COVID-19 in the United States: A model based analysis
Vincent Daniels, Kunal Saxena, Craig Roberts, Smita Kothari, … Linda Niccolai
Pages 2731-2735

Hesitancy towards COVID-19 Vaccination among Healthcare Workers: A Multi-Centric Survey in France

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Vaccines — Open Access Journal
http://www.mdpi.com/journal/vaccines

 

(Accessed 22 May 2021)
Open Access Article
Hesitancy towards COVID-19 Vaccination among Healthcare Workers: A Multi-Centric Survey in France
by Cécile Janssen et al and on behalf of the ACV Alpin Study Group
Vaccines 2021, 9(6), 547; https://doi.org/10.3390/vaccines9060547 (registering DOI) – 22 May 2021
Abstract
Vaccination programs against COVID-19 are being scaled up. We aimed to assess the effects of vaccine characteristics on vaccine hesitancy among healthcare workers in a multi-center survey conducted within French healthcare facilities from 1 December 2020 to 26 March 2021. We invited any […]

COVID-19 Vaccine Acceptability and Adherence to Preventive Measures in Somalia: Results of an Online Survey

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Vaccines — Open Access Journal
http://www.mdpi.com/journal/vaccines

 

Open Access Article
COVID-19 Vaccine Acceptability and Adherence to Preventive Measures in Somalia: Results of an Online Survey
by Mohammed A. M. Ahmed et al
Vaccines 2021, 9(6), 543; https://doi.org/10.3390/vaccines9060543 (registering DOI) – 21 May 2021
Abstract
Most countries are currently gravitating towards vaccination as mainstay strategy to quell COVID-19 transmission. Between December 2020 and January 2021, we conducted a follow-up online survey in Somalia to monitor adherence to COVID-19 preventive measures, and COVID-19 vaccine acceptability and reasons for vaccine [..