Organization Announcements

Organization Announcements
Editor’s Note:
Careful readers will note that the number and range of organizations now monitored in our Announcements section below has grown as the impacts of the pandemic have spread across global economies, supply chains and programmatic activity of multilateral agencies and INGOs.

 

Paul G. Allen Frontiers Group [to 24 Jul 2021]
https://alleninstitute.org/what-we-do/frontiers-group/news-press/
News
No new digest content identified.

 

BARDA – U.S. Department of HHS [to 24 Jul 2021]
https://www.phe.gov/about/barda/Pages/default.aspx
News
No new digest content identified.

 

BMGF – Gates Foundation [to 24 Jul 2021]
https://www.gatesfoundation.org/ideas/media-center
Press Releases and Statements
No new digest content identified.

 

Bill & Melinda Gates Medical Research Institute [to 24 Jul 2021]
https://www.gatesmri.org/
The Bill & Melinda Gates Medical Research Institute is a non-profit biotech organization. Our mission is to develop products to fight malaria, tuberculosis, and diarrheal diseases—three major causes of mortality, poverty, and inequality in developing countries. The world has unprecedented scientific tools at its disposal; now is the time to use them to save the lives of the world’s poorest people
No new digest content identified.

 

CARB-X [to 24 Jul 2021]
https://carb-x.org/
News
No new digest content identified.

 

Center for Vaccine Ethics and Policy – GE2P2 Global Foundation [to 24 Jul 2021]
https://centerforvaccineethicsandpolicy.net/
News/Analysis/Statements
:: Past weekly editions and posting of all segments of Vaccines and Global Health: The Week in Review are available here.
:: [NEW] Informed Consent: A Monthly Review – July 2021 is now posted here

 

CEPI – Coalition for Epidemic Preparedness Innovations [to 24 Jul 2021]
http://cepi.net/
Latest News
CEPI partners with Shanghai Zerun Biotech to develop COVID-19 variant vaccine
CEPI will provide US$13.1 million to advance development of both COVID-19 prototype and variant vaccine candidates.
COVAX 21 Jul 2021

CEPI and IVI collaborate on clinical research to expand access to COVID-19 vaccines in Africa
New programme of clinical research in Mozambique aims to support the expanded use of the BBIBP-CorV vaccine in Africa.
COVID-19 20 Jul 2021

 

CIOMS – COUNCIL FOR INTERNATIONAL ORGANIZATIONS OF MEDICAL SCIENCES [to 24 Jul 2021]
https://cioms.ch/
News; Publications
No new digest content identified.

 

DARPA – Defense Advanced Research Projects Agency [to 24 Jul 2021
https://www.darpa.mil/news
News
No new digest content identified.

 

Duke Global Health Innovation Center [to 24 Jul 2021]
https://dukeghic.org/
How can LMIC countries prepare to receive and efficiently administer large numbers of COVID-19 vaccine doses?
Melissa Slogan July 16, 2021

 

EDCTP [to 24 Jul 2021]
http://www.edctp.org/
The European & Developing Countries Clinical Trials Partnership (EDCTP) aims to accelerate the development of new or improved drugs, vaccines, microbicides and diagnostics against HIV/AIDS, tuberculosis and malaria as well as other poverty-related and neglected infectious diseases in sub-Saharan Africa, with a focus on phase II and III clinical trials
No new digest content identified.

 

Emory Vaccine Center [to 24 Jul 2021]
http://www.vaccines.emory.edu/
Vaccine Center News
No new digest content identified.

 

European Vaccine Initiative [to 24 Jul 2021]
http://www.euvaccine.eu/
Latest News
No new digest content identified

 

FDA [to 24 Jul 2021]
https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/default.htm
Press Announcements
July 23, 2021 – Coronavirus (COVID-19) Update: July 23, 2021
:: A new FDA Voices, Global Regulators Envision Paradigm Shift Toward Inclusion of Pregnant and Breastfeeding Women in Clinical Research for Medicines and Vaccines, describes efforts being made to address inadequacies in research through a paradigm shift in the approach to studying medical products in pregnant and breastfeeding women.

July 20, 2021 – Coronavirus (COVID-19) Update: July 20, 2021
:: This week, at the FDA SBIA REdI Annual Conference, FDA leaders reflected on the FDA’s use of Emergency Use Authorizations (EUAs) and other resources in making drug, device and biological products available to support the public health response to the COVID-19 pandemic. Day 1External Link Disclaimer and Day 2External Link Disclaimer recordings are now available on YouTube. The conference c
ontinues through Friday, with additional sessionsExternal Link Disclaimer on devices and biologics.
:: Last week, the FDA held a stakeholder call to discuss COVID-19 vaccines, including preliminary reports of Guillain-Barré Syndrome following Janssen COVID-19 vaccination. HereExternal Link Disclaimer is an excerpt from that call where Dr. Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research discussed the importance of getting vaccinated.
:: An FDA Consumer Update, Learn More About COVID-19 Vaccines From the FDA, is now available in five additional languages: Spanish, Chinese, Korean, Tagalog, and Vietnamese. See the evidence for each COVID-19 vaccine and the reasoning behind the FDA’s Emergency Use Authorizations (EUAs).

 

Fondation Merieux [to 24 Jul 2021]
http://www.fondation-merieux.org/
News, Events
No new digest content identified.

 

Gavi [to 24 Jul 2021]
https://www.gavi.org/
News Releases
23 July 2021
First doses donated by Japan to COVAX reach lower-income countries

 

GHIT Fund [to 24 Jul 2021]
https://www.ghitfund.org/newsroom/press
GHIT was set up in 212 with the aim of developing new tools to tackle infectious diseases that
No new digest content identified.

 

Global Fund [to 24 Jul 2021]
https://www.theglobalfund.org/en/news/
News & Stories
No new digest content identified.

 

Global Research Collaboration for Infectious Disease Preparedness [GloPID-R] [to 24 Jul 2021]
https://www.glopid-r.org/news/
News
No new digest content identified.

 

Hilleman Laboratories [to 24 Jul 2021]
http://www.hillemanlabs.org/
Website reports “under maintenance” at inquiry

 

Human Vaccines Project [to 24 Jul 2021]
http://www.humanvaccinesproject.org/
News
News webpage not responding at inquiry

 

IAVI [to 24 Jul 2021]
https://www.iavi.org/newsroom
Latest News
No new digest content identified.

 

 

International Coalition of Medicines Regulatory Authorities [ICMRA]
http://www.icmra.info/drupal/en/news
Selected Statements, Press Releases, Research
No new digest content identified.

 

ICRC [to 24 Jul 2021]
https://www.icrc.org/en/whats-new
Selected News Releases, Statements, Reports
Afghanistan: Civilians paying steep price of surge in violence and COVID-19
ICRC activities in Afghanistan, one of the the deadliest places in the world to be a civilian, and women and children make up nearly half of all civilian casualties.
21-07-2021 | News release

 

 

International Generic and Biosimilar Medicines Association [IGBA]
https://www.igbamedicines.org/
News
No new digest content identified.

 

 

IFFIm
http://www.iffim.org/
Press Releases/Announcements
No new digest content identified.

 

IFRC [to 24 Jul 2021]
http://media.ifrc.org/ifrc/news/press-releases/
Selected Press Releases, Announcements
No new digest content identified.

 

Institut Pasteur [to 24 Jul 2021]
https://www.pasteur.fr/en/press-area
Press Documents
Press release 16.07.2021
ComCor study: analysis of the effectiveness of messenger RNA vaccines against the SARS-CoV-2 Alpha and Beta variants in France
Over the past six months, the World Health Organization has categorized four SARS-CoV-2 variants as being “of concern”…

 

IOM / International Organization for Migration [to 24 Jul 2021]
http://www.iom.int/press-room/press-releases
News
No new digest content identified.

 

IRC International Rescue Committee [to 24 Jul 2021]
http://www.rescue.org/press-release-index
Media highlights [Selected]
No new digest content identified.

 

IVAC [to 24 Jul 2021]
https://www.jhsph.edu/research/centers-and-institutes/ivac/index.html
Updates; Events
Webinar: Preventing the Next Pandemic: Vaccine Diplomacy, Surveillance and COVID Vaccines
When: Jul 30, 2021 at 11:00 AM Eastern Time
Description: Join Dr. Peter Hotez for a 60-minute webinar hosted by the International Vaccine Access Center to discuss topics ranging from vaccine diplomacy, the antivaccine movement, safety surveillance, and a new COVID vaccine.

 

IVI [to 24 Jul 2021]
http://www.ivi.int/
Selected IVI News, Announcements, Events
CEPI and IVI collaborate on clinical research to expand access to COVID-19 vaccines in Africa
July 20, 2021; Oslo, Norway and Seoul, Republic of Korea: The Coalition for Epidemic Preparedness Innovations (CEPI) and the International Vaccine Institute (IVI) today announced a new programme of clinical research which aims to expand access to COVID-19 vaccines in Africa. CEPI will provide funding of up to $12.7m to the Expanding Access and Delivery of COVID-19 Vaccines in Africa (ECOVA) consortium led by IVI to carry out clinical trials of Sinopharm’s BBIBP-CorV vaccine which will support the expanded use of the vaccine on the African continent.
Up to 170 million doses of BBIBP-CorV will be distributed by the COVAX Facility under an agreement announced on 12 July 2021, and the vaccine is already being deployed in over 50 countries around the world. However there have been no clinical trials of BBIBP-CorV in African populations or against the variants of concern circulating in southern Africa. The ECOVA research programme aims to generate crucial data to inform the use of the vaccine in Africa, and potentially expand use of the vaccine to HIV-infected individuals. All results generated by ECOVA will be made available open source to inform policy makers and regulatory authorities’ recommendations on the use of BBIBP-CorV in national immunization programmes…
The ECOVA consortium is led by IVI, working in partnership with Mozambique’s Instituto Nacional de Saúde (INS), the International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), the University of Heidelberg, Germany (UH), Harvard University, USA, and the University of Antananarivo in Madagascar (UA)…

 

JEE Alliance [to 24 Jul 2021]
https://www.jeealliance.org/
Selected News and Events
No new digest content identified.

 

Johns Hopkins Center for Health Security [to 24 Jul 2021]
https://www.centerforhealthsecurity.org/news/center-news/
Center News
No new digest content identified.

 

MSF/Médecins Sans Frontières [to 24 Jul 2021]
http://www.msf.org/
Latest [Selected Announcements]
South Africa
Supporting overstretched health centres and vulnerable communities in the aftermath of the violence
Project Update 23 Jul 2021

Mediterranean migration
MSF requests the revocation of the Geo Barents’ detention
Open Letter 23 Jul 2021

Central African Republic
Repeated attacks on medical care leave people vulnerable to disease and death
Press Release 19 Jul 2021

 

National Academy of Medicine – USA [to 24 Jul 2021]
https://nam.edu/programs/
Selected News/Programs
Discussion Paper Offers Guidance on Identifying Credible Sources of Health Information in Social Media
July 21, 2021
WASHINGTON — A new individually authored discussion paper in NAM Perspectives — the digital periodical of the National Academy of Medicine — outlines principles and attributes that social media platforms can use to identify potentially credible sources of health information online.

 

National Academy of Sciences – USA [to 24 Jul 2021]
http://www.nasonline.org/news-and-multimedia/
News
As Surgeon General Urges ‘Whole-of-Society’ Effort to Fight Health Misinformation the Work of the National Academies Helps Foster an Evidence-Based Information Environment
July 14, 2021
The U.S. surgeon general has released a public advisory calling misinformation a ‘serious threat to public health.’ The National Academies have been addressing misinformation in health and science on multiple fronts and are taking steps to help cultivate a fact- and evidence-based information environment.

 

National Vaccine Program Office – U.S. HHS [to 24 Jul 2021]
https://www.hhs.gov/vaccines/about/index.html
Upcoming Meetings/Latest Updates
No new digest content identified.

 

NIH [to 24 Jul 2021]
http://www.nih.gov/news-events/news-releases
News Releases
Tuesday, July 20, 2021
More than 1.5 million children lost a primary or secondary caregiver due to the COVID-19 pandemic
Addressing the impact of caregiver deaths critical for pediatric mental health, authors note.

 

PATH [to 24 Jul 2021]
https://www.path.org/media-center/
Press Releases
No new digest content identified.

 

Sabin Vaccine Institute [to 24 Jul 2021]
http://www.sabin.org/updates/pressreleases
Statements and Press Releases
No new digest content identified.

 

UNAIDS [to 24 Jul 2021]
http://www.unaids.org/en
Selected Press Releases/Reports/Statements
23 July 2021
2021 ECOSOC resolution on the Joint Programme adopted by consensus

22 July 2021
UNAIDS saddened by the death of Cyriaque Yapo Ako

22 July 2021
Changing the landscape of community engagement in the HIV response in Indonesia

21 July 2021
An HIV vaccine: who needs it?

21 July 2021
2025 AIDS targets: the next generation of goals for the global AIDS response

19 July 2021
Opening session of the IAS Conference on HIV Science

19 July 2021
KFF/UNAIDS analysis finds that while donor government spending on HIV increased in 2020, future funding is uncertain with COVID-19 challenges

 

UNHCR Office of the United Nations High Commissioner for Refugees [to 24 Jul 2021]
http://www.unhcr.org/en-us/media-centre.htmlS
Selected News Releases, Announcements
Record numbers forced to flee ongoing violence in Burkina Faso
23 Jul 2021

UNICEF [to 24 Jul 2021]
https://www.unicef.org/media/press-releases
Press Releases, News Notes, Statements [Selected]
Statement 07/19/2021
Statement by UNICEF Executive Director Henrietta Fore on children deprived of parental care due to COVID-19
NEW YORK, 19 July 2021 – “As the official COVID-19 death toll around the world passed 4 million earlier this month, UNICEF is increasingly concerned for children left without one or both parents.
“As with all crises and health pandemics, the most vulnerable children are at increased risk of losing parental care – due to death, severe illness or financial hardship. This in turn increases their risk of being placed in unsuitable alternative care.
“While it’s too early to estimate the number of children orphaned or abandoned as a result of the pandemic, a spike in deaths in some countries means many children already vulnerable to the impacts of COVID-19 face further emotional distress and protection concerns…

 

Unitaid [to 24 Jul 2021]
https://unitaid.org/
Featured News
No new digest content identified.

Vaccine Equity Initiative [to 24 Jul 2021]
https://vaccineequitycooperative.org/news/
News
No new digest content identified.

 

Vaccination Acceptance & Demand Initiative [Sabin) [to 24 Jul 2021]
https://www.vaccineacceptance.org/
Announcements
No new digest content identified.

 

Vaccine Confidence Project [to 24 Jul 2021]
http://www.vaccineconfidence.org/
News, Research and Reports
Coronavirus global impact
Launched April 2, 2020 and recurring every 3 days, Premise Data is utilizing its global network of Contributors to assess economic, social, and health sentiment surrounding the coronavirus (COVID-19).

 

Vaccine Education Center – Children’s Hospital of Philadelphia [to 24 Jul 2021]
http://www.chop.edu/centers-programs/vaccine-education-center
News
No new digest content identified.

 

Wellcome Trust [to 24 Jul 2021]
https://wellcome.ac.uk/news
News and reports
No new digest content identified.

 

The Wistar Institute [to 24 Jul 2021]
https://www.wistar.org/news/press-releases
Press Releases
Jul. 20, 2021
Wistar Scientists Discovered Fundamental and Widespread Gene Expression Control Mechanism that Potentially Creates Proteins at Distinct Locations in the Cell, with Implications in Immunity and Cancers
Through alternative polyadenylation, RNA molecules are directed to sites of protein synthesis to facilitate production of certain proteins where they are most needed.

 

WFPHA: World Federation of Public Health Associations [to 24 Jul 2021]
https://www.wfpha.org/
Latest News
No new digest content identified.

 

World Bank [to 24 Jul 2021]
http://www.worldbank.org/en/news/all
Selected News, Announcements
World Bank Group’s $157 Billion Pandemic Surge Is Largest Crisis Response in Its History
In response to COVID-19 severely damaging the lives and livelihoods of millions of people in developing countries, the World Bank Group deployed over $157 billion to fight the pandemic’s health, economic, and social impacts over the last 15 months (April 1, 2020 – June 30, 2021). This is the largest crisis response of any such period in the Bank Group’s history and represents an increase of more than 60% over the 15-month period prior to the pandemic. Bank Group commitments and mobilizations in fiscal year 2021 (FY21) alone (July 1, 2020 – June 30, 2021) amounted to almost $110 billion (or $84 billion excluding mobilization, short-term financing, and recipient-executed trust funds).
Since the start of the pandemic, the Bank Group supported countries to address the health emergency, strengthen health systems, protect the poor and vulnerable, support businesses, create jobs and jump start a green, resilient, and inclusive recovery.
Following last year’s COVID-related economic deterioration, the global economy is expected to expand 5.6% in 2021. Thus far, the recovery is uneven and many of the world’s poorest countries are being left behind. While about 90% of advanced economies are expected to regain their pre-pandemic per capita income levels by 2022, only about one-third of emerging market and developing economies are projected to do the same. In 2020, global extreme poverty rose for the first time in over 20 years, with nearly 100 million people pushed into extreme poverty.
Date: July 19, 2021 Type: Press Release

Health Emergency Preparedness and Response (HEPR) Umbrella Program
Supporting better health emergency preparedness and more effective responses
Given the urgency for stronger global health security and the need to help developing countries get better prepared for disease outbreaks, the World Bank Group established the new Health Emergency Preparedness and Response (HEPR) Umbrella Program to support eligible countries and territories to improve their capacities to prepare for, prevent, respond and mitigate the impact of epidemics on people.
The HEPR Umbrella Program provides financing to low-income countries and to countries with low health emergency preparedness and response capabilities. The program was set up earlier this year to support low-income countries and countries with struggling health emergency responses in building resilience and increasing investments in health preparedness – including their immediate COVID-19 response. It is an important tool in the World Bank’s pandemic response and longer-term health preparedness in countries that need support and their most vulnerable communities, including refugees.
Financial support is also available for countries that are unable to access regular for World Bank financing because they are in arrears with their payments to the International Development Association (IDA), and to Jordan and Lebanon for supporting Syrian refugees. Looking ahead, the program seeks to support more countries to meet critical needs.
Date: July 19, 2021 Type: Brief

 

World Customs Organization – WCO [to 24 Jul 2021]
http://www.wcoomd.org/
Latest News – Selected Items
23 July 2021
The role of Customs presented in a WHO-WTO High-Level Dialogue on expanding COVID-19 vaccine manufacturing

20 July 2021
The WCO Environment Programme engages with 11 Customs administrations in the field of illegal wildlife trade

 

World Organisation for Animal Health (OIE) [to 24 Jul 2021]
https://www.oie.int/en/for-the-media/press-releases/2021/
Press Releases, Statements
Editorial
Responding to emergencies through preparedness and resilience
19 July 2021
The COVID-19 pandemic has impacted almost all walks of life and it has required a multisectoral and interdisciplinary approach to respond to this global emergency.
Monique Éloit, Director General, World Organisation for Animal Health (OIE)

 

WTO – World Trade Organisation [to 24 Jul 2021]
http://www.wto.org/english/news_e/news_e.htm
WTO News and Events
WHO-WTO dialogue steps up efforts for increased COVID-19 vaccine production and equitable access
21 July 2021
The World Health Organization (WHO) and the WTO on 21 July hosted a High-Level Dialogue on “Expanding COVID-19 vaccine manufacture to promote equitable access”, with the participation of senior policymakers, heads of multilateral agencies, vaccine manufacturers, development finance institutions, global health initiatives and public health activists.

High-Level Dialogue on “Expanding COVID-19 vaccine manufacture to promote equitable access”
21 July 2021
Remarks by DG Okonjo-Iweala

TRIPS Council agrees to continue discussions on IP response to COVID-19
20 July 2021
At a meeting of the Council for Trade-Related Aspects of Intellectual Property Rights (TRIPS) on 20 July 2021, WTO members agreed to continue consideration of the proposal for a temporary waiver of certain TRIPS obligations in response to COVID-19 and other related proposals. Members approved a status report which they tasked the chair to deliver at the General Council at its next meeting on 27-28 July.

WTO publishes list of bottlenecks and facilitating measures on critical COVID-19 products
20 July 2021
The WTO Secretariat has issued an indicative list of trade-related bottlenecks and trade-facilitating measures on critical products to combat COVID-19, including inputs used in vaccine manufacturing, vaccine distribution and approval, therapeutics and pharmaceuticals, diagnostics and medical devices. The list is being released in advance of a High-Level Dialogue by the World Health Organization (WHO) and the WTO on 21 July on expanding COVID-19 vaccines manufacturing to promote equitable access.

::::::

 

ARM [Alliance for Regenerative Medicine] [to 24 Jul 2021]
Press Releases – Alliance for Regenerative Medicine (alliancerm.org)
Selected Press Releases
No new digest content identified.

 

BIO [to 24 Jul 2021]
https://www.bio.org/press-releases
Press Releases, Letters, Testimony, Comments [Selected]
No new digest content identified.

 

DCVMN – Developing Country Vaccine Manufacturers Network [to 24 Jul 2021]
http://www.dcvmn.org/
News; Upcoming events
No new digest content identified.

 

ICBA – International Council of Biotechnology Associations [to 24 Jul 2021]
https://internationalbiotech.org/news/
News
No new digest content identified.

 

IFPMA [to 24 Jul 2021]
http://www.ifpma.org/resources/news-releases/
Selected Press Releases, Statements, Publications
IFPMA Statement at WTO-WHO High Level Dialogue “Expanding COVID-19 Vaccine Manufacture to Promote Equitable Access”
21 July 2021
[See COVID above for detail]

 

International Alliance of Patients’ Organizations – IAPO [to 24 Jul 2021]
https://www.iapo.org.uk/news/topic/6
Press and media [Selected]
Patient empowerment can unlock the benefits of self-care
Thursday, 22 July 2021
Self-care activities are an essential component of patient-centered health care systems. The World Health Organization defines self-care as “the ability of individuals, families, and communities to promote health, prevent disease, maintain health, and to cope with illness and disability with or without the support of a healthcare provider.”

 

PhRMA [to 24 Jul 2021]
http://www.phrma.org/
Latest News [Selected]
Dose sharing as a part of the COVID-19 global vaccine equity strategy
July 20, 2021
Dose sharing is one of the strategies helping to accelerate work to broaden global access to COVID-19 vaccines…
…With millions of doses either shared or making their way to nations in need, we are already seeing the benefits of dose sharing as a strategy to promote COVID-19 vaccine equity. Leaders should focus on this and other meaningful solutions to ensure more shots are administered to more people.
Rather than pursuing misguided proposals to waive international commitments to protect intellectual property (IP) for COVID-19 innovations, industry supports practical strategies like dose sharing that better serve low- and middle-income nations while also upholding the IP ecosystem that made COVID-19 innovation possible.
Blog Post

Journal Watch

Journal Watch
Vaccines and Global Health: The Week in Review continues its weekly scanning of key peer-reviewed journals to identify and cite articles, commentary and editorials, books reviews and other content supporting our focu-s on vaccine ethics and policy. Journal Watch is not intended to be exhaustive, but indicative of themes and issues the Center is actively tracking. We selectively provide full text of some editorial and comment articles that are specifically relevant to our work. Successful access to some of the links provided may require subscription or other access arrangement unique to the publisher.
If you would like to suggest other journal titles to include in this service, please contact David Curry at: david.r.curry@centerforvaccineethicsandpolicy.org

Spatial Inequities in COVID-19 Testing, Positivity, Confirmed Cases, and Mortality in 3 U.S. Cities

Annals of Internal Medicine
July 2021 Volume 174, Issue 7
http://annals.org/aim/issue

 

Original Research
Spatial Inequities in COVID-19 Testing, Positivity, Confirmed Cases, and Mortality in 3 U.S. Cities
An Ecological Study
FREE
Usama Bilal, PhD, Loni P. Tabb, PhD, Sharrelle Barber, ScD, Ana V. Diez Roux, PhD Pages:936–944

Health Information Privacy, Protection, and Use in the Expanding Digital Health Ecosystem: A Position Paper of the American College of Physicians

Annals of Internal Medicine
July 2021 Volume 174, Issue 7
http://annals.org/aim/issue

 

Position Papers
Health Information Privacy, Protection, and Use in the Expanding Digital Health Ecosystem: A Position Paper of the American College of Physicians
FREE
Brooke Rockwern, MPH, Dejaih Johnson, JD, MPA, Lois Snyder Sulmasy, JD,
Pages:994–998
Abstract
Technologic advancements and the evolving digital health landscape have offered innovative solutions to several of our health care system’s issues as well as increased the number of digital interactions and type of personal health information that is generated and collected, both within and outside of traditional health care. This American College of Physicians’ position paper discusses the state of privacy legislation and regulations, highlights existing gaps in health information privacy protections, and outlines policy principles and recommendations for the development of health information privacy and security protections that are comprehensive, transparent, understandable, adaptable, and enforceable. The principles and recommendations aim to improve on the privacy framework in which physicians have practiced for decades and expand similar privacy guardrails to entities not currently governed by privacy laws and regulations. The expanded privacy framework should protect personal health information from unauthorized, discriminatory, deceptive, or harmful uses and align with the principles of medical ethics, respect individual rights, and support the culture of trust necessary to maintain and improve care delivery.

Toward Understanding COVID-19 Recovery: National Institutes of Health Workshop on Postacute COVID-19

Annals of Internal Medicine
July 2021 Volume 174, Issue 7
http://annals.org/aim/issue

 

Special Articles
Toward Understanding COVID-19 Recovery: National Institutes of Health Workshop on Postacute COVID-19
FREEAndrea M. Lerner, MD, Daphne A. Robinson, PhD, Linda Yang, PhD, Carolyn F. Williams, PhD, MPH, … et al.
Pages:999–1003

Gurus and Griots: Revisiting the research informed consent process in rural African contexts

BMC Medical Ethics
http://www.biomedcentral.com/bmcmedethics/content
(Accessed 24 Jul 2021)

 

Gurus and Griots: Revisiting the research informed consent process in rural African contexts
Researchers conducting community-based participatory action research (CBPAR) in highly collectivistic and socioeconomically disadvantaged community settings in sub-Saharan Africa are confronted with the distinctive challenge of balancing universal ethical standards with local standards, where traditional customs or beliefs may conflict with regulatory requirements and ethical guidelines underlying the informed consent (IC) process. The unique ethnic, socioeconomic, and cultural diversities in these settings have important implications for the IC process, such as individual decisional autonomy, beneficence, confidentiality, and signing the IC document.
Authors: Richard Appiah
Citation: BMC Medical Ethics 2021 22:98
Content type: Debate
Published on: 23 July 2021

E-health roadmap for COVID-19 vaccine coverage in Iran

BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 24 Jul 2021)

 

E-health roadmap for COVID-19 vaccine coverage in Iran
Vaccination is the effective and long-term pharmacological solution to deal with COVID-19. Information technology (IT) and electronic immunization can be effective in accelerating and improving vaccine coverag…
Authors: Elham Maserat, Leila Keikha, Somayeh Davoodi and Zeinab Mohammadzadeh
Citation: BMC Public Health 2021 21:1450
Content type: Research
Published on: 23 July 2021

Beliefs and barriers associated with COVID-19 vaccination among the general population in Saudi Arabia

BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 24 Jul 2021)

 

Beliefs and barriers associated with COVID-19 vaccination among the general population in Saudi Arabia
Developing a vaccine against COVID-19 is considered a key strategy to end the pandemic. However, public acceptance is reliant on beliefs and perception toward the vaccine. Therefore, the study aimed to assess …
Authors: Rania M. Magadmi and Fatemah O. Kamel
Citation: BMC Public Health 2021 21:1438
Content type: Research article
Published on: 21 July 2021

Effectiveness of participant recruitment strategies for critical care trials: A systematic review and narrative synthesis

Clinical Trials

Volume 18 Issue 4, August 2021

https://journals.sagepub.com/toc/ctja/18/4

 

Recruitment and Retention
Effectiveness of participant recruitment strategies for critical care trials: A systematic review and narrative synthesis
Timia Raven-Gregg, Fiona Wood, Victoria Shepherd
First Published February 2, 2021; pp. 436–448

Supplement: E-Mental-Health: Exploring the Evidence Base and Stakeholders’ Perspectives on Internet-Based Interventions for the Prevention of Mental Health Conditions

The European Journal of Public Health
SUPPLEMENT – Volume 31, Issue Supplement_1, July 2021
https://academic.oup.com/eurpub/issue/31/Supplement_1

 

Supplement: E-Mental-Health: Exploring the Evidence Base and Stakeholders’ Perspectives on Internet-Based Interventions for the Prevention of Mental Health Conditions
Mental illness represents an enormous personal, social and societal burden for European citizens1 calling for the need to expand existing models of mental healthcare delivery. In Europe, the Internet is a key source of health information,2 and technology-enhanced (psychological) interventions such as Internet- and mobile-delivered applications (‘eHealth’3 and ‘m-Health’4) have become increasingly popular and studied. There is already strong evidence of the efficacy of online interventions for the prevention and treatment of several psychological disorders5,6 and meta-analyses show effect sizes similar to face-to-face interventions.7

Conflict and COVID-19 in Yemen: beyond the humanitarian crisis

Globalization and Health
http://www.globalizationandhealth.com/
[Accessed 24 Jul 2021]

 

Conflict and COVID-19 in Yemen: beyond the humanitarian crisis
Yemen has been left in shambles and almost destroyed by its devastating civil war, and is now having to deal with the spread of coronavirus. The Yemeni people have been are left to fend for themselves and face…
Authors: Mohammed Alsabri, Ayman Alhadheri, Luai M. Alsakkaf and Jennifer Cole
Citation: Globalization and Health 2021 17:83
Content type: Commentary
Published on: 22 July 2021

July 2021 | Borders, Immigrants & Health

Health Affairs
Vol. 40, No. 7 July 2021
https://www.healthaffairs.org/toc/hlthaff/current

 

July 2021 | Borders, Immigrants & Health
About one in seven residents of the US is an immigrant, and about fifteen million people live within 100 kilometers of the US-Mexico border. Disparities in health status exist between people born in the US and those who have immigrated. Immigration policy has been contentious throughout US history, and current policies in the US and Mexico have significant effects on the health and well-being of tens of millions of people. This thematic issue of Health Affairs focuses on immigrants and borders. The overview article by Arturo Vargas Bustamante and coauthors describes a range of health policy issues raised by the continuously shifting demography of US immigrants.

Rethinking approaches of science, technology, and innovation in healthcare during the COVID-19 pandemic: the challenge of translating knowledge infrastructures to public needs

Health Research Policy and Systems
http://www.health-policy-systems.com/content
[Accessed 24 Jul 2021]

 

Rethinking approaches of science, technology, and innovation in healthcare during the COVID-19 pandemic: the challenge of translating knowledge infrastructures to public needs
Authors: Renan Gonçalves Leonel da Silva, Roger Chammas and Hillegonda Maria Dutilh Novaes
Content type: Commentary
21 July 2021
Introduction
The coronavirus 2019 (COVID-19) pandemic has changed how we understand and approach problems in science, technology, and innovation (ST&I) in health in contemporary society. The current situation has produced specific demands for health systems, and an inconvenient paradox has become visible: we have never had such a supply of qualified scientific and technological knowledge infrastructures in health and biomedical sciences, but at the same time a viable translation of this knowledge to public health systems has shown itself flawed and inefficient. This paradox raises questions about what has brought us to this inconvenient reality, and the importance of paying greater attention to the mechanisms of governance and implementation of ST&I in public health in a more systemic way.

Localisation and local humanitarian action

Humanitarian Exchange Magazine
Number 79, May 2021
https://odihpn.org/magazine/inclusion-of-persons-with-disabilities-in-humanitarian-action-what-now/

 

Localisation and local humanitarian action
by HPN October 2020
The theme of this edition of Humanitarian Exchange is localisation+ and local humanitarian action. Five years ago this week, donors, United Nations (UN) agencies,  non-governmental organisations (NGOs), the International Committee of the Red Cross (ICRC) and International Federation of Red Cross and Red Crescent Societies (IFRC) committed within the Grand Bargain to increase multi-year investments in the institutional capacities of local and national responders, and to provide at least 25% of humanitarian funding to them as directly as possible. Since then, there is increasing consensus at policy and normative level, underscored by the Covid-19 pandemic, that local leadership should be supported.  Localisation has gone from a fringe conversation among policy-makers and aid agencies in 2016 to a formal priority under the Grand Bargain. Wider global movements on anti-racism and decolonisation have also brought new momentum to critical reflections on where power, knowledge and capacity reside in the humanitarian system. Yet progress has been slow and major gaps remain between the rhetoric around humanitarian partnerships, funding and coordination and practices on the ground.

Multi-level determinants of failure to receive timely and complete measles vaccinations in Southwest China: a mixed methods study

Infectious Diseases of Poverty
http://www.idpjournal.com/content
[Accessed 24 Jul 2021]

 

Multi-level determinants of failure to receive timely and complete measles vaccinations in Southwest China: a mixed methods study
Authors: Xian-Yan Tang, Man Cheng, Alan Geater, Qiu-Yun Deng, Ge Zhong, Yue-Dong Lin, Ning Chen, Tao Lan, Long-Yan Jiang, Man-Tong Zhu and Qiao Li
Content type: Research Article
22 July 2021

Guidelines for Reporting Trial Protocols and Completed Trials Modified Due to the COVID-19 Pandemic and Other Extenuating CircumstancesThe CONSERVE 2021 Statement

JAMA
July 20, 2021, Vol 326, No. 3, Pages 207-286
https://jamanetwork.com/journals/jama/currentissue

 

Special Communication
Guidelines for Reporting Trial Protocols and Completed Trials Modified Due to the COVID-19 Pandemic and Other Extenuating CircumstancesThe CONSERVE 2021 Statement
Aaron M. Orkin, MD, MSc, MPH; Peter J. Gill, MD, DPhil; Davina Ghersi, MD, PhD; et al.
free access
JAMA. 2021;326(3):257-265. doi:10.1001/jama.2021.9941
This Special Communication describes CONSERVE, a guideline developed to improve the transparency, quality, and completeness of reporting of trials and trial protocols that undergo important modifications in response to extenuating circumstances such as the COVID-19 pandemic.

Sharing Technology and Vaccine Doses to Address Global Vaccine Inequity and End the COVID-19 Pandemic

JAMA
July 20, 2021, Vol 326, No. 3, Pages 207-286
https://jamanetwork.com/journals/jama/currentissue

 

Viewpoint
Sharing Technology and Vaccine Doses to Address Global Vaccine Inequity and End the COVID-19 Pandemic
Matthew M. Kavanagh, PhD; Lawrence O. Gostin, JD; Madhavi Sunder, JD
free access
JAMA. 2021;326(3):219-220. doi:10.1001/jama.2021.10823
This Viewpoint offers 3 strategies to address inequity in pandemic vaccine response: surge funding, increased funding, and an agreement to share technology and allow countries to waive intellectual property rights in global public health emergencies.

Ethical Considerations of Offering Benefits to COVID-19 Vaccine Recipients

JAMA
July 20, 2021, Vol 326, No. 3, Pages 207-286
https://jamanetwork.com/journals/jama/currentissue

 

Ethical Considerations of Offering Benefits to COVID-19 Vaccine Recipients
Govind Persad, JD, PhD; Ezekiel J. Emanuel, MD, PhD
free access
JAMA. 2021;326(3):221-222. doi:10.1001/jama.2021.11045
This Viewpoint discusses why offering incentives for COVID-19 vaccination is not only ethical, but an important tool in increasing vaccine uptake, which benefits society as a whole.

Overview of the Issue

Journal of Health Care for the Poor and Underserved (JHCPU)
Volume 32, Number 2, May 2021 Supplement
https://muse.jhu.edu/issue/44396

 

Table of Contents
Overview of the Issue
Kevin B. Johnson, Tiffani J. Bright, Cheryl R. Clark
…The importance of techquity—defined as the strategic development and deployment of technology in health care and health to advance health equity—was even more apparent after the events of 2020. COVID-19 upended access to care and illuminated the impact of structural racism as a cause for a widening gap of access during the pandemic. Black Lives Matter became more than a trending hashtag on Twitter, or a movement resulting in peaceful protests and calls for policy reform: it put additional focus on the issue of race as a social and not a biological construct and called into question the rationale for common practices in health care that were triggered by race. A notable example was the emerging realization that kidney function assessment was tied to race and hardwired into many of our electronic health records. The real-world evidence around our lack of techquity was incontrovertible.
This Supplemental Issue of JHCPU provides articles that describe challenges to techquity, frameworks to improve the role of technology in care, and examples of how technology can transform health, public health, and health care…

Five priorities for universal COVID-19 vaccination

The Lancet
Jul 17, 2021 Volume 398 Number 10296 p185-276, e7
https://www.thelancet.com/journals/lancet/issue/current

 

Comment
Five priorities for universal COVID-19 vaccination
Adrien Abecassis
… On May 6, 2021, the Paris Peace Forum (PPF), an international platform dedicated to global governance, convened a high-level meeting, which included government officials and G20 sherpas to heads of states and governments, public health leaders, and members of non-governmental organisations and foundations from 15 countries, to deliberate on how to get closer to universal COVID-19 vaccination in a limited time. The group identified five priorities…

BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans

Nature
Volume 595 Issue 7868, 22 July 2021
https://www.nature.com/nature/volumes/595/issues/7868

 

Article | 27 May 2021
BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans
In a phase-I/II trial in healthy adults, the BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells against SARS-CoV-2 epitopes that are conserved in a wide range of currently circulating variants.
Ugur Sahin, Alexander Muik…Özlem Türeci

Evidence-informed policy for tackling adverse climate change effects on health: Linking regional and global assessments of science to catalyse action

PLoS Medicine
http://www.plosmedicine.org/
(Accessed 24 Jul 2021)

 

Evidence-informed policy for tackling adverse climate change effects on health: Linking regional and global assessments of science to catalyse action
Robin Fears, Khairul Annuar B. Abdullah, Claudia Canales-Holzeis, Deoraj Caussy, Andy Haines, Sherilee L. Harper, Jeremy N. McNeil, Johanna Mogwitz, Volker ter Meulen
Policy Forum | published 20 Jul 2021 PLOS Medicine
https://doi.org/10.1371/journal.pmed.1003719

Addressing antimicrobial resistance by improving access and quality of care—A review of the literature from East Africa

PLoS Neglected Tropical Diseases
http://www.plosntds.org/

 

Review
Addressing antimicrobial resistance by improving access and quality of care—A review of the literature from East Africa
Kathrin Loosli, Alicia Davis, Adrian Muwonge, Tiziana Lembo
| published 22 Jul 2021 PLOS Neglected Tropical Diseases
https://doi.org/10.1371/journal.pntd.0009529

Ethical review of COVID-19 research in the Netherlands; a mixed-method evaluation among medical research ethics committees and investigators

PLoS One
http://www.plosone.org/
[Accessed 24 Jul 2021]

 

Ethical review of COVID-19 research in the Netherlands; a mixed-method evaluation among medical research ethics committees and investigators
R. IJkema, M. J. P. A. Janssens, J. A. M. van der Post, C. M. Licht
Research Article | published 23 Jul 2021 PLOS ONE
https://doi.org/10.1371/journal.pone.0255040

Collective insights of public-private partnership impacts and sustainability: A qualitative analysis

PLoS One
http://www.plosone.org/
[Accessed 24 Jul 2021]

 

Collective insights of public-private partnership impacts and sustainability: A qualitative analysis
Sheryl Strasser, Christine Stauber, Ritu Shrivastava, Patricia Riley, Karen O’Quin
Research Article | published 20 Jul 2021 PLOS ONE
https://doi.org/10.1371/journal.pone.0254495

Modeling vaccination strategies in an Excel spreadsheet: Increasing the rate of vaccination is more effective than increasing the vaccination coverage for containing COVID-19

PLoS One
http://www.plosone.org/
[Accessed 24 Jul 2021]

 

Modeling vaccination strategies in an Excel spreadsheet: Increasing the rate of vaccination is more effective than increasing the vaccination coverage for containing COVID-19
Mario Moisés Alvarez, Sergio Bravo-González, Grissel Trujillo-de Santiago
Research Article | published 19 Jul 2021 PLOS ONE
https://doi.org/10.1371/journal.pone.0254430

Transmission dynamics are crucial to COVID-19 vaccination policy

PNAS – Proceedings of the National Academy of Sciences of the United States of America
July 20, 2021; vol. 118 no. 29
https://www.pnas.org/content/118/29

 

Transmission dynamics are crucial to COVID-19 vaccination policy
Jonathan Dushoff, Caroline Colijn, David J. D. Earn, and Benjamin M. Bolker
PNAS July 20, 2021 118 (29) e2105878118; https://doi.org/10.1073/pnas.2105878118

Reply to Dushoff et al. and Pifarré i Arolas et al.: Age prioritization for COVID-19 vaccination does save lives and years of life

PNAS – Proceedings of the National Academy of Sciences of the United States of America
July 20, 2021; vol. 118 no. 29
https://www.pnas.org/content/118/29

 

Reply to Dushoff et al. and Pifarré i Arolas et al.: Age prioritization for COVID-19 vaccination does save lives and years of life
Joshua R. Goldstein, Thomas Cassidy, and Kenneth W. Wachter
PNAS July 20, 2021 118 (29) e2107654118; https://doi.org/10.1073/pnas.2107654118

Transparent communication about negative features of COVID-19 vaccines decreases acceptance but increases trust

PNAS – Proceedings of the National Academy of Sciences of the United States of America
July 20, 2021; vol. 118 no. 29
https://www.pnas.org/content/118/29

 

Psychological and Cognitive Sciences
Open Access
Transparent communication about negative features of COVID-19 vaccines decreases acceptance but increases trust
Michael Bang Petersen, Alexander Bor, Frederik Jørgensen, and Marie Fly Lindholt
PNAS July 20, 2021 118 (29) e2024597118; https://doi.org/10.1073/pnas.2024597118

Research integrity: emphasising our commitment

Research Ethics
Volume 17 Issue 3, July 2021
http://journals.sagepub.com/toc/reab/current

 

Editorial
Research integrity: emphasising our commitment
Stuart G. Nicholls
First Published July 19, 2021
It is just over a year since the editors of this journal announced a broadening of the remit for submission. In doing so they made an explicit commitment to supporting work that examines research integrity issues. Furthering this commitment, we announce that Dr Edward Dove has joined Research Ethics as Associate Editor, with a focus on overseeing manuscripts that concern research integrity and/or misconduct matters.

As detailed in the previous editorial, research integrity is a counterpart to research ethics. Where research ethics focuses more on research governance at the programme or study level, research integrity takes as its focus the researcher themselves, emphasising the values and virtues of those conducting research. The Canadian Council of Academies research integrity framework, for example, articulates values of honesty, fairness, trust, accountability and openness as being key to research integrity (Davenport et al., 2010). A concrete example of efforts to improve research integrity is seen through the push for Open Science and research reporting guidelines (Glasziou et al., 2014; Nicholls et al., 2016). The use of reporting guidelines to facilitate more transparent and complete publication practices promotes what Masic (2012) calls ‘intellectual honesty’; being straightforward in description of the research process. When reporting guidelines are combined with what O’Neill (2002) has described as the ‘audit agenda’ and the ‘openness agenda’, the completeness and transparency of reporting can be assessed through peer review more easily. This, in turn, promotes trust in research findings and reporting, and ultimately the research process.

Research integrity is at the core of several papers in this issue. For instance, in their study of ethical issues in internet research and research using online data, Stommel and de Rijk examine how ethical issues are reported, and in what ways, as well as the steps that authors take to protect the privacy of the sources of publicly available online data. They note that almost two thirds of the 132 articles they examined did not report ethical considerations yet commonly took steps to anonymise data. Notably, the discussion of ethical issues was highly variable with discrepancies between ethics principles in theory and in practice.

Online platforms also feature in the work of Littler and Joy, although their focus is on the use of social media for research recruitment, specifically within LGBTQ communities. Littler and Joy examine the researcher role as gatekeepers. They reflect on what they have learned from their experience of negative hate speech posted in response to recruitment adverts on social media, and the impact it has on them as researchers. They conclude that it is incumbent upon researchers to become experts in the use and misuse of social media if they are to use these platforms for recruitment in research.

The impact of research on the researchers themselves, is also picked up by Podschuweit, who reports on quantitative covert observational research and the processes they employed to help student researchers deal with their personal discomfort in observing personal interactions. The findings show how mentally stressful covert observations can be for the student observers and suggestions are made for preparing students appropriately.

Finally, Reid et al. report on the development of a toolkit for global researchers designed to help navigate ethical challenges that they face when conducting research. They note that sharing experiences is an all too rare activity that is not generally encouraged within the competitive academic environment. Foundational to their work is the view that research integrity and research ethics matters are ongoing throughout the study, and not just about gaining ethics approval. The authors offer the 4P (place, people, principles and precedent) framework as a guiding structure to assist researchers approach ethical dilemmas that occur outside of the ethics approval process.

We hope that this collection of papers, as well as the other excellent manuscripts included in this issue, inspire readers to continue to examine and publish on matters of research integrity. We look forward to welcoming these at Research Ethics.

Colleges need vaccine mandates

Science
23 July 2021 Vol 373, Issue 6553
http://www.sciencemag.org/current.dtl

 

Editorial
Colleges need vaccine mandates
By H. Holden Thorp
Summary
Finally, in the United States, colleges and universities are ramping up for a relatively normal school year. Most pandemic restrictions have been lifted and—barring any unforeseen new coronavirus variants—parents and students will soon be pulling up to residence halls and unloading their belongings. At many schools in “blue” states, there will be a great deal of confidence that good times are on the horizon as everyone there will have shown proof of vaccination against COVID-19. But for some public universities in “red” states, where vaccine mandates are not permitted, an aura of uncertainty will hang over the campus and the local community, a foreboding sense that another outbreak could be at hand.

WHO chief pressures China on pandemic origin

Science
23 July 2021 Vol 373, Issue 6553
http://www.sciencemag.org/current.dtl

 

In-Depth
WHO chief pressures China on pandemic origin
By Jon Cohen
Science23 Jul 2021 : 378 Restricted Access
Agency director calls for lab audits and more studies of how SARS-CoV-2 emerged.
Summary
In a sharp tightening of the diplomatic screws, the director-general of the World Health Organization (WHO), Tedros Adhanom Ghebreyesus, is urging China to increase its transparency about the early days of the COVID-19 pandemic and allow greater access to its labs to help resolve the origin of SARS-CoV-2. Tedros also says WHO will create a new body to conduct the next phase of studies into the emergence of the virus, an unexpected move that concerns some scientists, including at least one member of an existing mission the agency organized to study COVID-19’s origin. Tedros called for more aggressively probing the two leading theories of how SARS-CoV-2 first infected humans and then emerged in Wuhan, China, in December 2019: that the virus made a natural “zoonotic” jump from an unknown animal species into humans or, more controversially, that it first infected a human during laboratory or field studies of coronaviruses found in animals. (An even more contentious theory suggests the virus was genetically engineered in a Wuhan lab.)

The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance

Science Translational Medicine
21 July 2021 Vol 13, Issue 603
https://stm.sciencemag.org/

 

Research Articles
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance
By James M. Murithi, Cécile Pascal, Jade Bath, Xavier Boulenc, Nina F. Gnädig, Charisse Flerida A. Pasaje, Kelly Rubiano, Tomas Yeo, Sachel Mok, Sylvie Klieber, Paul Desert, María Belén Jiménez-Díaz, Jutta Marfurt, Mélanie Rouillier, Mohammed H. Cherkaoui-Rbati, Nathalie Gobeau, Sergio Wittlin, Anne-Catrin Uhlemann, Ric N. Price, Grennady Wirjanata, Rintis Noviyanti, Patrick Tumwebaze, Roland A. Cooper, Philip J. Rosenthal, Laura M. Sanz, Francisco Javier Gamo, Jayan Joseph, Shivendra Singh, Sridevi Bashyam, Jean Michel Augereau, Elie Giraud, Tanguy Bozec, Thierry Vermat, Gilles Tuffal, Jean-Michel Guillon, Jérôme Menegotto, Laurent Sallé, Guillaume Louit, Marie-José Cabanis, Marie Françoise Nicolas, Michel Doubovetzky, Rita Merino, Nadir Bessila, Iñigo Angulo-Barturen, Delphine Baud, Lidiya Bebrevska, Fanny Escudié, Jacquin C. Niles, Benjamin Blasco, Simon Campbell, Gilles Courtemanche, Laurent Fraisse, Alain Pellet, David A. Fidock, Didier Leroy
Science Translational Medicine21 Jul 2021 Full Access
We report an acylguanidine preclinical candidate with pharmacological features compatible with single low-dose malaria cure.
Antimalarial advance
The need for antimalarial drugs is urgent in the face of growing resistance to existing therapies. Murithi et al. characterized MMV688533, an acylguanidine identified from compounds inhibiting known human drug targets that were screened for activity against Plasmodium falciparum. MMV688533 showed rapid in vitro killing of multiple P. falciparum strains as well as P. vivax. A single dose of MMV688533 rapidly reduced parasitemia in a P. falciparum NSG mouse model of infection, and this agent displayed favorable pharmacokinetic and toxicity profiles. MMV688533 selected for only low-grade resistance, with resistant parasites remaining sensitive to existing antimalarials. These findings suggest that MMV688533 is a promising antimalarial candidate with a low resistance risk and the promise of a single-dose cure, which merits further study.

Methodologic approaches in studies using real-world data (RWD) to measure pediatric safety and effectiveness of vaccines administered to pregnant women: A scoping review

Vaccine
Volume 39, Issue 29 Pages 3785-4012 (29 June 2021)
https://www.sciencedirect.com/journal/vaccine/vol/39/issue/29

 

Review article Abstract only
Methodologic approaches in studies using real-world data (RWD) to measure pediatric safety and effectiveness of vaccines administered to pregnant women: A scoping review
Tamar Lasky, Ann W. McMahon, Wei Hua, Richard Forshee
Pages 3814-3824

Health inequities related to vaccination: An evidence map of potentially influential factors and systematic review of interventions

Vaccine
Volume 39, Issue 29 Pages 3785-4012 (29 June 2021)
https://www.sciencedirect.com/journal/vaccine/vol/39/issue/29

 

Review article Open access
Health inequities related to vaccination: An evidence map of potentially influential factors and systematic review of interventions
Allison Gates, Sholeh Rahman, Shannon Sim, Jennifer Pillay, … Lisa Hartling
Pages 3825-3833

Examining Vaccine Hesitancy in Sub-Saharan Africa: A Survey of the Knowledge and Attitudes among Adults to Receive COVID-19 Vaccines in Ghana

Vaccines — Open Access Journal
http://www.mdpi.com/journal/vaccines

 

Open Access Article
Examining Vaccine Hesitancy in Sub-Saharan Africa: A Survey of the Knowledge and Attitudes among Adults to Receive COVID-19 Vaccines in Ghana
by Theophilus Acheampong et al
Vaccines 2021, 9(8), 814; https://doi.org/10.3390/vaccines9080814 – 22 Jul 2021
Abstract
The impact of COVID-19 vaccination programmes on disease transmission, morbidity and mortality relies heavily on the population’s willingness to accept the vaccine. We explore Ghanaian adult citizens’ vaccine hesitancy attitudes and identify the likelihood of participation or non-participation in the government’s effort to […

Who Is Willing to Get Vaccinated? A Study into the Psychological, Socio-Demographic, and Cultural Determinants of COVID-19 Vaccination Intentions

Vaccines — Open Access Journal
http://www.mdpi.com/journal/vaccines

 

Open Access Article
Who Is Willing to Get Vaccinated? A Study into the Psychological, Socio-Demographic, and Cultural Determinants of COVID-19 Vaccination Intentions
by Giuliani Mattia et al
Vaccines 2021, 9(8), 810; https://doi.org/10.3390/vaccines9080810 – 21 Jul 2021
Abstract
Crucial to the success of the COVID-19 vaccination campaign is the rate of people who adhere to it. This study aimed to investigate the reasons underlying people’s willingness to get vaccinated in a sample of Italian adults, considering the effects of different individual […]