Influenza in the school-aged population in Mexico: burden of disease and cost-effectiveness of vaccination in children

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BMC Infectious Diseases
http://www.biomedcentral.com/bmcinfectdis/content
(Accessed 21 Mar 2020)

 

Influenza in the school-aged population in Mexico: burden of disease and cost-effectiveness of vaccination in children
The current national influenza vaccination schedule in Mexico does not recommend vaccination in the school-aged population (5–11 years). Currently, there are limited data from middle-income countries analysing…
Authors: Jorge Abelardo Falcón-Lezama, Rodrigo Saucedo-Martínez, Miguel Betancourt-Cravioto, Myrna María Alfaro-Cortes, Roberto Isaac Bahena-González and Roberto Tapia-Conyer
Citation: BMC Infectious Diseases 2020 20:240
Content type: Research article
Published on: 20 March 2020

Dishonesty and research misconduct within the medical profession

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BMC Medical Ethics
http://www.biomedcentral.com/bmcmedethics/content
(Accessed 21 Mar 2020)

Dishonesty and research misconduct within the medical profession
Authors: Habib Rahman and Stephen Ankier
Content type: Review
18 March 2020
Abstract
While there has been much discussion of how the scientific establishment’s culture can engender research misconduct and scientific irreproducibility, this has been discussed much less frequently with respect to the medical profession. Here the authors posit that a lack of self-criticism, an encouragement of novel scientific research generated by the recruitment policies of the UK Royal Training Colleges along with insufficient training in the sciences are core reasons as to why research misconduct and dishonesty prevail within the medical community. Furthermore, the UK General Medical Council’s own data demonstrates a historic inattentiveness to the ease with which doctors can engage in research misconduct. Suggestions are made as to how these issues can be investigated and alternative incentives for career advancement are adumbrated.

Clarifying how to deploy the public interest criterion in consent waivers for health data and tissue research

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BMC Medical Ethics
http://www.biomedcentral.com/bmcmedethics/content
(Accessed 21 Mar 2020)

 

Clarifying how to deploy the public interest criterion in consent waivers for health data and tissue research
Several jurisdictions, including Singapore, Australia, New Zealand and most recently Ireland, have a public interest or public good criterion for granting waivers of consent in biomedical research using secondary health data or tissue. However, the concept of the public interest is not well defined in this context, which creates difficulties for institutions, institutional review boards (IRBs) and regulators trying to implement the criterion.
Authors: G. Owen Schaefer, Graeme Laurie, Sumytra Menon, Alastair V. Campbell and Teck Chuan Voo
Content type: Debate
20 March 2020

 

Vaccination coverage with the pneumococcal and influenza vaccine among persons with chronic diseases in Shanghai, China, 2017

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BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 21 Mar 2020)

 

Vaccination coverage with the pneumococcal and influenza vaccine among persons with chronic diseases in Shanghai, China, 2017
Adults with chronic conditions such as heart disease, diabetes, or lung disease are more likely to develop complications from a number of vaccine-preventable diseases, including influenza and pneumonia. In thi…
Authors: Yuheng Wang, Minna Cheng, Siyuan Wang, Fei Wu, Qinghua Yan, Qinping Yang, Yanyun Li, Xiang Guo, Chen Fu, Yan Shi, Abram L. Wagner and Matthew L. Boulton
Citation: BMC Public Health 2020 20:359
Content type: Research article
Published on: 19 March 2020

Quantifying the success of measles vaccination campaigns in the Rohingya refugee camps

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Epidemics
Volume 30 March 2020
https://www.sciencedirect.com/journal/epidemics/vol/30/suppl/C

 

Research article Open access
Quantifying the success of measles vaccination campaigns in the Rohingya refugee camps
Taylor Chin, Caroline O. Buckee, Ayesha S. Mahmud
Article 100385
Abstract
In the wake of the Rohingya population’s mass migration from Myanmar, one of the world’s largest refugee settlements was constructed in Cox’s Bazar, Bangladesh to accommodate nearly 900,000 new refugees. Refugee populations are particularly vulnerable to infectious disease outbreaks due to many population and environmental factors. A large measles outbreak, with over 1700 cases, occurred among the Rohingya population between September and November 2017. Here, we estimate key epidemiological parameters and use a dynamic mathematical model of measles transmission to evaluate the effectiveness of the reactive vaccination campaigns in the refugee camps. We also estimate the potential for subsequent outbreaks under different vaccination coverage scenarios. Our modeling results highlight the success of the vaccination campaigns in rapidly curbing transmission and emphasize the public health importance of maintaining high levels of vaccination in this population, where high birth rates and historically low vaccination coverage rates create suitable conditions for future measles outbreaks.

Research Participant Views regarding Qualitative Data Sharing

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Ethics & Human Research
Volume 42, Issue 2 Pages: 1-33 March–April 2020
https://onlinelibrary.wiley.com/toc/25782363/current

 

Incidental Findings :: Data Sharing N‐of‐1 Trials :: Deception
Articles
Research Participant Views regarding Qualitative Data Sharing
We found no studies in the United States that explored research participants’ perspectives about sharing their qualitative data. We present findings from interviews with 30 individuals who participated in sensitive qualitative studies to explore their understanding and concerns regarding qualitative data sharing. The vast majority supported sharing qualitative data so long as their data were deidentified and shared only among researchers. However, they raised concerns about confidentiality if the data were not adequately deidentified and about misuse by secondary users if data were shared beyond the research community.
Jessica Mozersky, Meredith Parsons, Heidi Walsh, Kari Baldwin, Tristan McIntosh, James M. DuBois
Pages: 13-27
First Published: 19 March 2020

Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review

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Infectious Diseases of Poverty
http://www.idpjournal.com/content
[Accessed 21 Mar 2020]

 

Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review
A scoping review was conducted following the methodological framework suggested by Arksey and O’Malley. In this scoping review, 65 research articles published before 31 January 2020 were analyzed and discussed to better understand the epidemiology, causes, clinical diagnosis, prevention and control of this virus. The research domains, dates of publication, journal language, authors’ affiliations, and methodological characteristics were included in the analysis. All the findings and statements in this review regarding the outbreak are based on published information as listed in the references.
Authors: Sasmita Poudel Adhikari, Sha Meng, Yu-Ju Wu, Yu-Ping Mao, Rui-Xue Ye, Qing-Zhi Wang, Chang Sun, Sean Sylvia, Scott Rozelle, Hein Raat and Huan Zhou
Content type: Scoping Review
17 March 2020

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

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JAMA
March 17, 2020, Vol 323, No. 11, Pages 1021-1104
http://jama.jamanetwork.com/issue.aspx

 

Original Investigation
Caring for the Critically Ill Patient
Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China
Dawei Wang, MD; Bo Hu, MD; Chang Hu, MD; et al.
free access has active quiz has multimedia has audio
JAMA. 2020;323(11):1061-1069. doi:10.1001/jama.2020.1585
This single-center case series describes the demographics, symptoms, laboratory and imaging findings, treatment, and clinical course of 138 patients hospitalized with 2019 novel coronavirus (2019-nCoV)–infected pneumonia (NCIP) in Wuhan, China, highlighting presumed human-to-human hospital-associated transmission in many cases.
Audio Interview: COVID-19 Update From China
Editorial
Editorial Concern—Possible Reporting of the Same Patients With COVID-19 in Different Reports
Howard Bauchner, MD; Robert M. Golub, MD; Jody Zylke, MD

Epidemiologic and Clinical Characteristics of Novel Coronavirus Infections Involving 13 Patients Outside Wuhan, China

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JAMA
March 17, 2020, Vol 323, No. 11, Pages 1021-1104
http://jama.jamanetwork.com/issue.aspx

 

Research Letter
Epidemiologic and Clinical Characteristics of Novel Coronavirus Infections Involving 13 Patients Outside Wuhan, China
De Chang, MD, PhD; Minggui Lin, MD; Lai Wei, MD; et al.
free access has active quiz has multimedia has audio
JAMA. 2020;323(11):1092-1093. doi:10.1001/jama.2020.1623
This case series uses patient hospital data to summarize the clinical presentation and laboratory and imaging findings of 13 patients with confirmed 2019-nCoV infection admitted to hospitals in Beijing in January 2020.

Randomized Clinical Trials of Artificial Intelligence

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JAMA
March 17, 2020, Vol 323, No. 11, Pages 1021-1104
http://jama.jamanetwork.com/issue.aspx

 

Editorial
Randomized Clinical Trials of Artificial Intelligence
Derek C. Angus, MD, MPH
JAMA. 2020;323(11):1043-1045. doi:10.1001/jama.2020.1039
As patient data are increasingly captured digitally, the opportunities to deploy artificial intelligence (AI), especially machine learning, are increasing rapidly. Machine learning is automated learning by computers using tools such as artificial neural networks to search data iteratively for optimal solutions.1 Typical applications include searching for novel patterns (eg, latent cancer subtypes2), making a diagnosis or outcome prediction (eg, diabetic retinopathy3), and optimizing treatment decisions (eg, fluid and vasopressor titration for septic shock4). Although many express excitement regarding the promise of AI, others express concern about adverse consequences, such as loss of physician and patient autonomy or unintended bias, and still others claim that the entire endeavor is largely hype, with virtually no data that actual patient outcomes have improved.5,6

Travellers give wings to novel coronavirus (2019-nCoV)

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Journal of Travel Medicine
Volume 27, Issue 2, March 2020
https://academic.oup.com/jtm/issue/27/2

 

Editorial
Travellers give wings to novel coronavirus (2019-nCoV)
Mary E Wilson, MD, Lin H Chen, MD
J Travel Med, Volume 27, Issue 2, March 2020, taaa015, https://doi.org/10.1093/jtm/taaa015
A novel coronavirus, probably of bat origin, has caused an outbreak of severe respiratory infection in humans in Wuhan, China and has been dispersed globally by travelers. The WHO has declared the spread of the infection a Public Health Emergency of International Concern.

Travellers give wings to novel coronavirus (2019-nCoV)

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Journal of Travel Medicine
Volume 27, Issue 2, March 2020
https://academic.oup.com/jtm/issue/27/2

 

Editorial
Travellers give wings to novel coronavirus (2019-nCoV)
Mary E Wilson, MD, Lin H Chen, MD
J Travel Med, Volume 27, Issue 2, March 2020, taaa015, https://doi.org/10.1093/jtm/taaa015
A novel coronavirus, probably of bat origin, has caused an outbreak of severe respiratory infection in humans in Wuhan, China and has been dispersed globally by travelers. The WHO has declared the spread of the infection a Public Health Emergency of International Concern.

Isolation, quarantine, social distancing and community containment: pivotal role for old-style public health measures in the novel coronavirus (2019-nCoV) outbreak

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Journal of Travel Medicine
Volume 27, Issue 2, March 2020
https://academic.oup.com/jtm/issue/27/2

 

Perspectives
Isolation, quarantine, social distancing and community containment: pivotal role for old-style public health measures in the novel coronavirus (2019-nCoV) outbreak
A Wilder-Smith, MD, D O Freedman, MD
J Travel Med, Volume 27, Issue 2, March 2020, taaa020, https://doi.org/10.1093/jtm/taaa020
Public health measures were decisive in controlling the SARS epidemic in 2003. Isolation is the separation of ill persons from non-infected persons. Quarantine is movement restriction, often with fever surveillance, of contacts when it is not evident whether they have been infected but are not yet symptomatic or have not been infected. Community containment includes measures that range from increasing social distancing to community-wide quarantine. Whether these measures will be sufficient to control 2019-nCoV depends on addressing some unanswered questions.

Are all vaccines safe for the pregnant traveller? A systematic review and meta-analysis

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Journal of Travel Medicine
Volume 27, Issue 2, March 2020
https://academic.oup.com/jtm/issue/27/2

 

Reviews
Are all vaccines safe for the pregnant traveller? A systematic review and meta-analysis
Roni Nasser, MD, Stav Rakedzon, MD, Yaakov Dickstein, MD, Amjad Mousa, MD, Ido Solt, MD …
J Travel Med, Volume 27, Issue 2, March 2020, taz074, https://doi.org/10.1093/jtm/taz074

Vaccination against Japanese encephalitis with IC51: systematic review on immunogenicity, duration of protection and safety

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Journal of Travel Medicine
Volume 27, Issue 2, March 2020
https://academic.oup.com/jtm/issue/27/2

 

Vaccination against Japanese encephalitis with IC51: systematic review on immunogenicity, duration of protection and safety
Kerstin Kling, Thomas Harder, Zane Younger, Gerd Burchard, Jonas Schmidt-Chanasit …
J Travel Med, Volume 27, Issue 2, March 2020, taaa016, https://doi.org/10.1093/jtm/taaa016

Potential for global spread of a novel coronavirus from China

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Journal of Travel Medicine
Volume 27, Issue 2, March 2020
https://academic.oup.com/jtm/issue/27/2

 

Potential for global spread of a novel coronavirus from China
Isaac I Bogoch, MD, Alexander Watts, PhD, Andrea Thomas-Bachli, PhD, Carmen Huber, MSA, Moritz U G Kraemer, DPhil …
J Travel Med, Volume 27, Issue 2, March 2020, taaa011, https://doi.org/10.1093/jtm/taaa011
An epidemic of a novel coronavirus emerged from Wuhan, China, in late December 2019 and has since spread to several large Chinese cities. Should a scenario arise where this coronavirus spreads more broadly across China, we evaluate how patterns of international disease transmission could change.

In emergencies, health research must go beyond public engagement toward a true partnership with those affected

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Nature Medicine
Volume 26 Issue 3, March 2020
https://www.nature.com/nm/volumes/26/issues/3

 

Comment | 28 January 2020
In emergencies, health research must go beyond public engagement toward a true partnership with those affected
An Ebola virus outbreak taking place in the complex political and social context of The Democratic Republic of the Congo has forced the research community to reflect on their approach to community engagement. Katharine Wright and Michael Parker, on behalf of the Nuffield Council on Bioethics Working Group on research in global health emergencies, say that those affected need to influence research choices from the very beginning and that the value of their knowledge must be recognized.
Katharine Wright, Michael Parker[…] & Paulina Tindana

The Dishonesty of Informed Consent Rituals

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New England Journal of Medicine
March 19, 2020 Vol. 382 No. 12
http://www.nejm.org/toc/nejm/medical-journal

 

Perspective
The Dishonesty of Informed Consent Rituals
Matt Bivens, M.D.
Out of respect for patient autonomy, we ritually inform patients of self-evident risks, even as we mock the very idea of informed consent by routinely prescribing combined medications that we must know will cost 10 times as much as the separate components.

Safety, tolerability, and immunogenicity of influenza vaccination with a high-density microarray patch: Results from a randomized, controlled phase I clinical trial

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PLoS Medicine
http://www.plosmedicine.org/
(Accessed 21 Mar 2020)

 

Research Article
Safety, tolerability, and immunogenicity of influenza vaccination with a high-density microarray patch: Results from a randomized, controlled phase I clinical trial
Angus H. Forster, Katey Witham, Alexandra C. I. Depelsenaire, Margaret Veitch, James W. Wells, Adam Wheatley, Melinda Pryor, Jason D. Lickliter, Barbara Francis, Steve Rockman, Jesse Bodle, Peter Treasure, Julian Hickling, Germain J. P. Fernando
Research Article | published 17 Mar 2020 PLOS Medicine
https://doi.org/10.1371/journal.pmed.1003024

Immunogenicity of a killed bivalent whole cell oral cholera vaccine in forcibly displaced Myanmar nationals in Cox’s Bazar, Bangladesh

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PLoS Neglected Tropical Diseases
http://www.plosntds.org/
(Accessed 21 Mar 2020)

 

Immunogenicity of a killed bivalent whole cell oral cholera vaccine in forcibly displaced Myanmar nationals in Cox’s Bazar, Bangladesh
Fahima Chowdhury, Taufiqur Rahman Bhuiyan, Afroza Akter, Md Saruar Bhuiyan, Ashraful Islam Khan, Motaher Hossain, Imam Tauheed, Tasnuva Ahmed, Shaumik Islam, Tanzeem Ahmed Rafique, Shah Alam Siddique, Nabila Binta Harun, Khaleda Islam, John D. Clemens, Firdausi Qadri
Research Article | published 16 Mar 2020 PLOS Neglected Tropical Diseases
https://doi.org/10.1371/journal.pntd.0007989
Abstract
After the large influx of Rohingya nationals (termed Forcibly Displaced Myanmar National; FDMN) from Rakhine State of Myanmar to Cox’s Bazar in Bangladesh, it was apparent that outbreaks of cholera was very likely in this setting where people were living under adverse water and sanitation conditions. Large campaigns of oral cholera vaccine (OCV) were carried out as a preemptive measure to control cholera epidemics. The aim of the study was to evaluate the immune responses of healthy adults and children after administration of two doses of OCV at 14 days interval in FDMN population and compare with the response observed in Bangladeshi’s vaccinated earlier. A cross-sectional immunogenicity study was conducted among FDMNs of three age cohort; in adults (18+years; n = 83), in older children (6–17 years; n = 63) and in younger children (1–5 years; n = 80). Capillary blood was collected at three time points to measure vibriocidal antibodies using either plasma or dried blood spot (DBS) specimens. There was a significant increase of responder frequency of vibriocidal antibody titer at day 14 in all groups for Vibrio cholerae O1 (Ogawa/Inaba: adults-64%/64%, older children-70%/89% and younger children-51%/75%). There was no overall difference of vibriocidal antibody titer between FDMN and Bangladeshi population at baseline (p = 0.07–0.08) and at day 14, day 28 in all age groups for both serotypes. The seroconversion rate and geometric mean titer (GMT) of either serotype were comparable using both plasma and DBS specimens. These results showed that OCV is capable of inducing robust immune responses in adults and children among the FDMN population which is comparable to that seen in Bangladeshi participants in different age groups or that reported from other cholera endemic countries. Our results also suggest that the displaced population were exposed to V. cholerae prior to seeking shelter in Bangladesh.

Knowledge gaps and acquisition about HPV and its vaccine among Brazilian medical students

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PLoS One
http://www.plosone.org/
[Accessed 21 Mar 2020]

 

Knowledge gaps and acquisition about HPV and its vaccine among Brazilian medical students
Annielson de Souza Costa, Jéssica Menezes Gomes, Ana Cláudia Camargo Gonçalves Germani, Matheus Reis da Silva, Edige Felipe de Sousa Santos, José Maria Soares Júnior, Edmund Chada Baracat, Isabel Cristina Esposito Sorpreso
Research Article | published 19 Mar 2020 PLOS ONE
https://doi.org/10.1371/journal.pone.0230058

Clinical trials of drug repositioning for COVID-19 treatment

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Revista Panamericana de Salud Pública/Pan American Journal of Public Health (RPSP/PAJPH)
https://www.paho.org/journal/en

 

Latest articles
20 Mar 2020
Clinical trials of drug repositioning for COVID-19 treatment
Brief communication | English |
Rosa and Santos
The World Health Organization (WHO) was informed in December 2019 about a coronavirus pneumonia outbreak in Wuhan, Hubei province (China). Subsequently, on March 12, 2020, 125,048 cases and 4,614 deaths were reported. Coronavirus is an enveloped RNA virus, from the genus Betacoronavirus, that is distributed in birds, humans, and other mammals. WHO has named the novel coronavirus disease as COVID-19. More than 80 clinical trials have been launched to test coronavirus treatment, including some drug repurposing or repositioning for COVID-19. Hence, we performed a search in March 2020 of the clinicaltrials.gov database. The eligibility criteria for the retrieved studies were: contain a clinicaltrials.gov base identifier number; describe the number of participants and the period for the study; describe the participants’ clinical conditions; and utilize interventions with medicines already studied or approved for any other disease in patients infected with the novel coronavirus SARS-CoV-2 (2019-nCoV). It is essential to emphasize that this article only captured trials listed in the clinicaltrials.gov database. We identified 24 clinical trials, involving more than 20 medicines, such as human immunoglobulin, interferons, chloroquine, hydroxychloroquine, arbidol, remdesivir, favipiravir, lopinavir, ritonavir, oseltamivir, methylprednisolone, bevacizumab, and traditional Chinese medicines (TCM). Although drug repurposing has some limitations, repositioning clinical trials may represent an attractive strategy because they facilitate the discovery of new classes of medicines; they have lower costs and take less time to reach the market; and there are existing pharmaceutical supply chains for formulation and distribution.

Time for NIH to lead on data sharing

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Science
20 March 2020 Vol 367, Issue 6484
http://www.sciencemag.org/current.dtl

 

Special Issue: Antarctica
Policy Forum
Time for NIH to lead on data sharing
By Ida Sim, Michael Stebbins, Barbara E. Bierer, Atul J. Butte, Jeffrey Drazen, Victor Dzau, Adrian F. Hernandez, Harlan M. Krumholz, Bernard Lo, Bernard Munos, Eric Perakslis, Frank Rockhold, Joseph S. Ross, Sharon F. Terry, Keith R. Yamamoto, Deborah A. Zarin, Rebecca Li
Science20 Mar 2020 : 1308-1309 Full Access
A draft policy is generally supportive but should start mandating data sharing
Summary
The U.S. National Institutes of Health (NIH), the largest global funder of biomedical research, is in the midst of digesting public comments toward finalizing a data sharing policy. Although the draft policy is generally supportive of data sharing (1), it needs strengthening if we are to collectively achieve a long-standing vision of open science built on the principles of findable, accessible, interoperable, and reusable (FAIR) (2) data sharing. Relying on investigators to voluntarily share data has not, thus far, led to widespread open science practices (3); thus, we suggest steps that NIH could take to lead on scientific data sharing, with an initial focus on clinical trial data sharing.

Insights into human genetic variation and population history from 929 diverse genomes

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Science
20 March 2020 Vol 367, Issue 6484
http://www.sciencemag.org/current.dtl

 

Research Articles
Insights into human genetic variation and population history from 929 diverse genomes
By Anders Bergström, Shane A. McCarthy, Ruoyun Hui, Mohamed A. Almarri, Qasim Ayub, Petr Danecek, Yuan Chen, Sabine Felkel, Pille Hallast, Jack Kamm, Hélène Blanché, Jean-François Deleuze, Howard Cann, Swapan Mallick, David Reich, Manjinder S. Sandhu, Pontus Skoglund, Aylwyn Scally, Yali Xue, Richard Durbin, Chris Tyler-Smith
Science20 Mar 2020 Restricted Access
Genomes from diverse human populations record human genetic diversity and illuminate the history of our species.
Genomes from around the globe
Genomic sequencing of diverse human populations to understand overall genetic diversity has lagged behind in-depth examination of specific populations. To add to our understanding of human genetic diversity, Bergström et al. generated whole-genome sequences surveying individuals in the Human Genome Diversity Project, which is a panel of global populations that has been instrumental in understanding the history of human populations. The authors’ study adds data about African, Oceanian, and Amerindian populations and indicates that diversity tends to result from differences at the single-nucleotide level rather than copy number variation. An analysis of archaic sequences in modern populations identifies ancestral genetic variation in African populations that likely predates modern humans and has been lost in most non-African populations.

Priorities for developing respiratory syncytial virus vaccines in different target populations

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Science Translational Medicine
18 March 2020 Vol 12, Issue 535
https://stm.sciencemag.org/

 

Review
Priorities for developing respiratory syncytial virus vaccines in different target populations
By Simon B. Drysdale, Rachael S. Barr, Christine S. Rollier, Christopher A. Green, Andrew J. Pollard, Charles J. Sande
Science Translational Medicine18 Mar 2020 Restricted Access
About 38 candidate vaccines and monoclonal antibodies are in clinical development for treating respiratory syncytial virus in different populations.

Strong vaccine responses during chemotherapy are associated with prolonged cancer survival

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Science Translational Medicine
18 March 2020 Vol 12, Issue 535
https://stm.sciencemag.org/

 

Research Articles
Strong vaccine responses during chemotherapy are associated with prolonged cancer survival
By Cornelis J. M. Melief, Marij J. P. Welters, Ignace Vergote, Judith R. Kroep, Gemma G. Kenter, Petronella B. Ottevanger, Wiebren A. A. Tjalma, Hannelore Denys, Mariette I. E. van Poelgeest, Hans W. Nijman, Anna K. L. Reyners, Thierry Velu, Frederic Goffin, Roy I. Lalisang, Nikki M. Loof, Sanne Boekestijn, Willem Jan Krebber, Leon Hooftman, Sonja Visscher, Brent A. Blumenstein, Richard B. Stead, Winald Gerritsen, Sjoerd H. van der Burg
Science Translational Medicine18 Mar 2020 Full Access
A strong vaccine-induced T cell response during standard-of-care chemotherapy correlates with survival in patients with advanced cervical cancer.

Tdap vaccination during pregnancy interrupts a twenty-year increase in the incidence of pertussis

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Vaccine
Volume 38, Issue 12 Pages 2643-2748 (10 March 2020)
https://www.sciencedirect.com/journal/vaccine/vol/38/issue/12

 

Research article Abstract only
Tdap vaccination during pregnancy interrupts a twenty-year increase in the incidence of pertussis
Dean Langsam, Emilia Anis, Eric J. Haas, Ruslan Gosinov, … Dan Yamin
Pages 2700-2706

Maternal knowledge and infant uptake of valid hepatitis B vaccine birth dose at routine immunization clinics in Enugu State – Nigeria

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Vaccine
Volume 38, Issue 12 Pages 2643-2748 (10 March 2020)
https://www.sciencedirect.com/journal/vaccine/vol/38/issue/12

 

Research article Abstract only
Maternal knowledge and infant uptake of valid hepatitis B vaccine birth dose at routine immunization clinics in Enugu State – Nigeria
Uchechukwu Joel Okenwa, Magbagbeola David Dairo, Eniola Bamgboye, Olufemi Ajumobi
Pages 2734-2740

Vaccination Perception and Attitude among Undergraduate Medical and Teacher Education Students at Charles University, Prague, Czech Republic

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Vaccines — Open Access Journal
http://www.mdpi.com/journal/vaccines
(Accessed 21 Mar 2020)

 

Open Access Article
Vaccination Perception and Attitude among Undergraduate Medical and Teacher Education Students at Charles University, Prague, Czech Republic
by Jiří Šálek , Alexander M. Čelko and Jana Dáňová
Vaccines 2020, 8(1), 136; https://doi.org/10.3390/vaccines8010136 – 19 Mar 2020
Abstract
This cross-sectional comparative study was designed to evaluate different opinions and their impact on vaccine confidence, as perceived by students of two different university programs (medicine and teacher education), as both of them play important roles in patient education, with the latter major shaping the skills of critical thinking. Multi-item, opinion-based, paper-and-pencil anonymous questionnaires were distributed among students of medicine and teacher education. Data were sorted and divided into two sets to be analyzed using logistic regression. Out of a total of 722 respondents, 386 were medical students and 336 were teacher education students. While most respondents said they were not in favor of alternative medicine, a significantly higher number of alternative medicine followers were teacher education students. The positive vaccination perception rate (PVPR) is not dependent on the behavioral factors of student respondents (irrespective of their major) but is largely affected by their attitude to alternative medicine. Fear of infection dramatically increased the PVPR (up to 6.7 times) in those who were versus were not afraid of getting infected or were not quite sure whether to fear it. Fear of side effects of vaccination clearly decreased the PVPR, by at least 84%

Media/Policy Watch

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Media/Policy Watch
This watch section is intended to alert readers to substantive news, analysis and opinion from the general media and selected think tanks and similar organizations on vaccines, immunization, global public health and related themes. Media Watch is not intended to be exhaustive, but indicative of themes and issues CVEP is actively tracking. This section will grow from an initial base of newspapers, magazines and blog sources, and is segregated from Journal Watch above which scans the peer-reviewed journal ecology.
We acknowledge the Western/Northern bias in this initial selection of titles and invite suggestions for expanded coverage. We are conservative in our outlook in adding news sources which largely report on primary content we are already covering above. Many electronic media sources have tiered, fee-based subscription models for access. We will provide full-text where content is published without restriction, but most publications require registration and some subscription level.

 

The Atlantic
http://www.theatlantic.com/magazine/
Accessed 21 Mar 2020
Ideas
The Crisis Could Last 18 Months. Be Prepared.
The shutdowns happened remarkably quickly, but the process of resuming our lives will be far more muddled.
21 Mar 2020 Juliette Kayyem
Former Department of Homeland Security official and author of Security Mom

Ideas
COVID-19 Vaccines Are Coming, but They’re Not What You Think
These novel approaches could fail in many ways.
21 Mar 2020

 

BBC
http://www.bbc.co.uk/
Accessed 21 Mar 2020
Health
Coronavirus: How close are we to a vaccine or drug?
By James Gallagher Health and science correspondent
20 March 2020

 

The Economist
http://www.economist.com/
Accessed 21 Mar 2020
[No new, unique, relevant content]

 

Financial Times
http://www.ft.com/home/uk
Accessed 21 Mar 2020
Coronavirus
Coronavirus patient shows encouraging immune system fightback
Woman in study makes recovery three days after doctors saw numerous infection-free cells
20 Mar 2020
The most detailed scientific study yet of a coronavirus patient has produced encouraging findings about the human immune system’s ability to fight the virus and help the body recover. Researchers at the Peter Doherty Institute for Infection and Immunity in Australia analysed blood samples from a previously healthy 47-year-old woman who contracted Covid-19 and found that her recovery was due to an unexpectedly strong immune response. The woman, whose blood was tested at four different points during the course of the disease, had travelled to Melbourne from Wuhan in China where Covid-19 originated…

 

Forbes
http://www.forbes.com/
Mar 21, 2020
Coronavirus Crisis Shines Light On Sustainability In Global Pharma And Medical Supply Chain
Will the rush to meet medical and pharmaceutical demand for COVID-19 testing and treatment, lead to a secondary environmental challenge.
By Nishan Degnarain Contributor

 

Foreign Affairs
http://www.foreignaffairs.com/
Accessed 21 Mar 2020
Pandemic Disease Is a Threat to National Security
As the United States now grapples with the 2019 novel coronavirus (COVID-19) epidemic, the time is long past to make pandemic disease a national security priority…
Lisa Monaco

Editors’ Pick  |
How Deforestation Drives The Emergence Of Novel Coronaviruses
Scientists have been warning for several years that deforestation is creating an accidental laboratory for the emergence of new viruses in environments that have been altered by humans.
By Jeff McMahon Senior Contributor

 

Foreign Policy
http://foreignpolicy.com/
Accessed 21 Mar 2020 Accessed 21 Mar 2020
[No new, unique, relevant content]

 

The Guardian
http://www.guardiannews.com/
Accessed 21 Mar 2020
[No new, unique, relevant content]

 

New Yorker
http://www.newyorker.com/
Accessed 21 Mar 2020
Q. & A.
The Coronavirus and Building a Better Strategy for Fighting Pandemics
“If we had got on top of this thing two months ago, America would look very, very different” right now, Ashish Jha, the director of the Harvard Global Health Institute, said.
By Isaac Chotiner March 20, 2020

 

New York Times
http://www.nytimes.com/
Accessed 21 Mar 2020
Family
Coronavirus Vaccine Dreams
If we get a vaccine for the coronavirus, it will immediately make our world a safer, easier, more reassuring place once again. That’s what vaccines do.
By Perri Klass, M.D. March 16

Health
Trial of Coronavirus Vaccine Made by Moderna Begins in Seattle
Healthy volunteers will test different doses of the first vaccine to find out if it is safe.
By Denise Grady

 

Washington Post
https://www.washingtonpost.com/
Accessed 21 Mar 2020
Where Are We in Quest for Coronavirus Drugs, Vaccine?: QuickTake
Mar 19, 2020

Think Tanks et al

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Think Tanks et al

Brookings
http://www.brookings.edu/
Accessed 21 Mar 2020
[No new relevant content]

Center for Global Development [to 21 Mar 2020]
http://www.cgdev.org/page/press-center
Selected Publications, News and Events
[No new relevant content]

 

CSIS
https://www.csis.org/
Accessed 21 Mar 2020
Podcast Episode
Coronavirus Crisis Update: Fmr. FDA Commissioner Dr. Margaret Hamburg on Testing and Where We Go From Here
March 20, 2020 | By J. Stephen Morrison, H. Andrew Schwartz

 

Council on Foreign Relations
http://www.cfr.org/
Accessed 21 Mar 2020
[No new relevant content]

 

Kaiser Family Foundation
https://www.kff.org/search/?post_type=press-release
Accessed 21 Mar 2020
[No new relevant content]