Milestones :: Perspectives :: Research
UNICEF COVID-19 Vaccine Market Dashboard :: Agreements Table Accessed 18 Sep 2021
An overview of information collected from publicly announced bilateral and multilateral supply agreements [agreements view since last week’s edition]
No new bilateral deals reported.
Milestones :: Perspectives :: Research
Duke – Launch and Scale Speedometer
The Race for Global COVID-19 Vaccine Equity
A flurry of nearly 200 COVID-19 vaccine candidates are moving forward through the development and clinical trials processes at unprecedented speed; more than ten candidates are already in Phase 3 large-scale trials and several have received emergency or limited authorization. Our team has aggregated and analyzed publicly available data to track the flow of procurement and manufacturing and better understand global equity challenges. We developed a data framework of relevant variables and conducted desk research of publicly available information to identify COVID vaccine candidates and status, deals and ongoing negotiations for procurement and manufacturing, COVID burden by country, and allocation and distribution plans. We have also conducted interviews with public officials in key countries to better understand the context and challenges facing vaccine allocation and distribution
[accessed 24 July 2021]
See our COVID Vaccine Purchases research
See our COVID Vaccine Manufacturing research
See our COVID Vaccine Donations & Exports research
Milestones :: Perspectives :: Research
Global Dashboard on COVID-19 Vaccine Equity
The Dashboard is a joint initiative of UNDP, WHO and the University of Oxford with cooperation across the UN system, anchored in the SDG 3 Global Action Plan for Healthy Lives and Well-being for All.
Dashboard on Vaccine Equity [accessed 18 Sep 2021]: https://data.undp.org/vaccine-equity/
See also visualization on Vaccine Access and Vaccine Affordability
Milestones :: Perspectives :: Research
Our World in Data
Coronavirus (COVID-19) Vaccinations [Accessed 18 Sep 2021]
42.9% of the world population has received at least one dose of a COVID-19 vaccine.
5.88 billion doses have been administered globally, and 29.49 million are now administered each day.
Only 1.9% of people in low-income countries have received at least one dose.
CDC – ACIP
Next ACIP Meetings
:: September 22, 2021, 10:00 a.m. – 5:00 p.m. and September 23, 2021, 11:00 a.m. – 2:00 p.m. is a virtual COVID-19 meeting at https://video.ibm.com/channel/VWBXKBR8af4 No registration is required to watch the webcast.
No Agenda posted at 18 Sep 2021.
Vaccines and Related Biological Products Advisory Committee- FDA
:: Vaccines and Related Biological Products Advisory Committee September 17, 2021
Agenda
The committee met in open session to discuss the Pfizer-BioNTech supplemental Biologics License Application for COMIRNATY for administration of a third dose, or “booster” dose, of the COVID-19 vaccine, in individuals 16 years of age and older.
YouTube recording: https://youtu.be/WFph7-6t34M
Editor’s Note:
No FDA announcement on action proceeding from this meeting was identified at 18 Sep 2021 – 1600/New York. We include the Pfizer announcement and coverage from the New York Times below for context:
FDA Advisory Committee Votes Unanimously in Favor Of COMIRNATY® Booster for Emergency Use in People 65 and Older and Certain High-risk Populations
09.17.2021
:: Committee reviewed clinical data showing a booster dose of COMIRNATY® elicits high neutralization titers against SARS-CoV-2 and all currently tested variants
:: Reactogenicity profile within seven days of the booster dose was typically mild to moderate, with frequency of reactions similar to or lower than after the primary vaccination series
:: Real-world data presented by Israel Ministry of Health show additional protection after receiving a booster translated to vaccine effectiveness comparable to levels seen early in the country’s vaccine rollout
:: FDA expected to make its decision in the coming days
NEW YORK & MAINZ, Germany–(BUSINESS WIRE)– Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) announced today that the U.S. Food and Drug Administration’s (FDA) Vaccines and Related Biological Products Advisory Committee (VRBPAC) voted unanimously to recommend the FDA grant Emergency Use Authorization (EUA) for a booster dose of COMIRNATY® (COVID-19 Vaccine, mRNA) in individuals 65 years of age and older and individuals at high risk of severe COVID-19. The committee recommended that the additional dose be administered at least six months after the two-dose series. The panel also agreed that healthcare workers and others at high risk for occupational exposure should be included in this EUA…
An FDA panel’s vote deals the Biden administration’s push for universal booster shots a setback.
New York Times, 17 Sep 2021
The Biden administration’s push to make Covid-19 booster shots available to most fully vaccinated adults has been stymied for now by a Food and Drug Administration advisory panel’s recommendation that Pfizer boosters be made available only to those 65 and over and those at high risk of severe Covid.
However, the roiling debate over whether the shots are needed more broadly remains unsettled.
The panel of experts on Friday overwhelmingly voted not to recommend boosters for those over 16 after a tense, daylong debate that put divisions within the agency and the administration on public display.
The vote was a blow to President Biden, strengthening criticism of his effort to enhance the immunity of already vaccinated Americans at a time when most residents of poor nations have not even had first doses. The F.D.A. and the Centers for Disease Control and Prevention authorized third shots for some immunocompromised individuals more than a month ago, on the ground that the additional dose would simply lift their protection to the level other people achieve with two shots.
Some F.D.A. experts said that the data from Pfizer and elsewhere still seemed to show that two shots protected against severe disease or hospitalization for months afterward, and that there was not enough evidence that a third shot would stem the spread of infection. Some also criticized a lack of data that an additional injection would be safe for younger people.
The panel’s final recommendations left some room for the White House to argue that the core of its booster strategy remained intact. Depending on how “at high risk” is defined, tens of millions of Americans could conceivably be deemed eligible for additional shots of the Pfizer vaccine. And a small but growing number of people have stopped waiting for federal authorization and are finding ways to receive booster shots…
White House [U.S.]
Briefing Room – Selected Major COVID Announcements
Press Briefing by White House COVID-19 Response Team and Public Health Officials
September 17, 2021 • Press Briefings
Statement by White House Press Secretary Jen Psaki on COVID-19 Summit
September 17, 2021 • Statements and Releases
[See Milestones above for detail]
Executive Order on Adding Measles to the List of Quarantinable Communicable Diseases
September 17, 2021 • Presidential Actions
Remarks by President Biden at a Meeting with Business Leaders and CEOs on the COVID-19 Response
September 15, 2021 • Speeches and Remarks
Europe: COVID-19 Vaccines – Announcements/Regulatory Actions/Deployment
European Medicines Agency
News & Press Releases
Meeting highlights from the Committee for Medicinal Products for Human Use (CHMP) 13-16 September 2021
News 17/09/2021
::::::
European Centre for Disease Prevention and Control
https://www.ecdc.europa.eu/en
Latest Updates
No new digest content identified
::::::
Data as of 2021-09-17
https://vaccinetracker.ecdc.europa.eu/public/extensions/COVID-19/vaccine-tracker.html#uptake-tab
::::::
European Commission
https://ec.europa.eu/commission/presscorner/home/en
Press release 17 September 2021
Commissioner Lenarčič visits Haiti as EU Humanitarian Air Bridge flight reaches the country
In the context of the continued EU support following the devastating earthquake that hit Haiti on 14 August, Commissioner for Crisis Management Janez Lenarčič is travelling to Haiti today.
Press release 16 September 2021
European Commission announces the New European Bauhaus prize winners
Today, the Commission announced the 20 winners of the ‘New European Bauhaus Awards’ and the ‘New European Bauhaus Rising Stars’.
New European Bauhaus website
Press release 15 September 2021
New European Bauhaus: new actions and funding to link sustainability to style and inclusion
Today, the Commission adopts a Communication setting out the concept of the New European Bauhaus.
Africa: COVID-19 – Announcements/Regulatory Actions/Deployment
[See Africa announcements in Milestones above]
Current at 09/01/2021 Full scale, interactive dashboard available at:
https://africacdc.org/covid-19-vaccination/
Russia: COVID-19 Vaccines – Announcements/Regulatory Actions/Deployment
Russia: Sputnik V – “the first registered COVID-19 vaccine”
https://sputnikvaccine.com/newsroom/pressreleases/
Press Releases
The single-component Sputnik Light vaccine authorized in Iran
Press release, 15.09.2021
Sputnik V demonstrates 97.2% efficacy and high safety profile against COVID during the vaccination campaign in Belarus
Press release, 15.09.2021
Study on Sputnik Light (first component of Sputnik V) vaccine’s efficacy among the elderly in Argentina published in EClinicalMedicine journal
Press release, 13.09.2021
India: COVID-19 Vaccines – Announcements/Regulatory Actions/Deployment
Ministry of Health and Family Welfare
https://www.mohfw.gov.in/
Latest Updates
No new digest content identified
Government of India – Press Information Bureau
Latest Press Releases
No new digest content identified
Indian Council for Medical Research (ICMR)
https://www.icmr.gov.in/media.html
Press Releases
No new digest content identified
China: COVID-19 Vaccines – Announcements/Regulatory Actions/Deployment
China surpasses 1 billion fully vaccinated
2021-09-17
China’s Chongqing to vaccinate foreign minors against COVID-19
2021-09-17
HONGQING — Southwest China’s Chongqing Municipality will administer COVID-19 vaccines to foreigners aged 12 to 17 from Saturday on a voluntary basis, according to the Chongqing Foreign Affairs Office.
Foreign citizens who are covered by the local health insurance program will enjoy the same policy as insured Chinese people, and those not covered will be charged 100 yuan (about 15.5 U.S. dollars) per dose.
The vaccines are domestically-developed inactivated COVID-19 vaccines, and a total of one or two doses may be required subject to different vaccines…
Emergencies
POLIO
Public Health Emergency of International Concern (PHEIC)
https://polioeradication.org/polio-today/polio-now/this-week/
Polio this week as of 15 September 2021
:: GPEI announced a series of commitments to advance gender equality at the Generation Equality Forum in Paris, organized by UN Women and hosted by the Governments of France and Mexico between June 30 and July 2, 2021. The Forum kickstarted a 5-year journey to accelerate ambitious action and implementation on global gender equality. Read more
Summary of new WPV and cVDPV viruses this week (AFP cases and ES positives):
:: Pakistan: three cVDPV2 positive environmental samples
:: Nigeria: 10 cVDPV2 cases
:: Mali: 1 cVDPV2 case
::::::
::::::
WHO/OCHA Emergencies
Editor’s Note:
WHO has apparently reorganized and fundamentally shifted how it judges and tracks “emergencies”. We found no announcement of descriptive information to share and present the webpage structure as encountered below. Obviously, the dates associated with some of these emergencies suggest that this is an archival platform as well as a current emergencies resource.
Health emergencies list – WHO
“The health emergencies list details the disease outbreaks, disasters and humanitarian crises where WHO plays an essential role in supporting countries to respond to and recover from emergencies with public health consequences.”
Crisis in Tigray, Ethiopia [Last apparent update: 5 Aug 2021]
Ebola outbreak, Democratic Republic of the Congo, 2021 [Last apparent update: 17 Aug 2021]
Ebola outbreak outbreak, N’Zerekore, Guinea, 2021 [Last apparent update: 17 Aug 2021]
Coronavirus disease (COVID-19) pandemic [See COVID above]
Ebola outbreak, Equateur Province, Democratic Republic of the Congo, 2020
[Last apparent update: 17 Aug 2021]
Ebola outbreak, North Kivu, Ituri, Democratic Republic of the Congo, 2018 – 2020
[Last apparent update: 17 Aug 2021]
Ebola outbreak, Democratic Republic of the Congo, 2018 [Last apparent update: 24 July 2018]
Yemen crisis [Last apparent update: 12 February 2021]
Syria crisis [Last apparent update: 18 June 2021]
Somalia crisis [Last apparent update: 24 March 2018]
Nigeria crisis [Last apparent update: 9 May 2018]
Ebola outbreak, Democratic Republic of the Congo, 2017 [Last apparent update: 17 Aug 2021]
Zika virus disease outbreak, 2015-2016 [Last apparent update: 24 Jan 2020]
Ebola outbreak: West Africa, 2014-2016 [Last apparent update: 17 Aug 2021]
Iraq crisis [Last apparent update: 9 Jan 2008]
South Sudan crisis [Last apparent update: 23 Sep 2020]
Avian influenza A (H7N9) virus outbreak
:: 13 September 2021 News release
Upcoming WHO Consultation on the Composition of Influenza Virus Vaccines for the Southern Hemisphere 2022
Middle East respiratory syndrome (MERS-CoV) outbreak [Last apparent update: 8 July 2019]
Influenza A (H1N1) virus, 2009-2010 pandemic [Last apparent update: 10 Aug 2010]
::::::
UN OCHA – Current Emergencies
Current Corporate Emergencies
Afghanistan
Afghanistan: Weekly Humanitarian Update (6 – 12 September 2021)
Northern Ethiopia
No new digest content identified
::::::
::::::
CDC/ACIP [U.S.] [to 18 Sep 2021]
http://www.cdc.gov/media/index.html
https://www.cdc.gov/vaccines/acip/index.html
Latest News Releases, Announcements
CDC to Invest $2.1 Billion to Protect Patients and Healthcare Workers from COVID-19 and Future Infectious Diseases
Friday, September 17, 2021
Today, the Biden-Harris Administration announced a $2.1 billion investment to improve infection prevention and control activities across the U.S. public health and healthcare sectors. The Biden-Harris Administration, working through the Centers for Disease Control and Prevention (CDC), is investing American Rescue Plan funding to strengthen and equip state, local, and territorial public health departments and other partner organizations with the resources needed to better fight infections in U.S. healthcare facilities, including COVID-19 and other known and emerging infectious diseases.
The funding announced today is a commitment that will allow the United States to expand public health and improve the quality of healthcare in our country, including addressing healthcare-related inequities. It will assist healthcare personnel to prevent infections more effectively in healthcare settings, support rapid response to detect and contain infectious organisms, enhance laboratory capacity, and engage in innovation targeted at combating infectious disease threats. Improvements in infection prevention will span the healthcare continuum, including 6,000 hospitals, 15,400 nursing homes and other long-term care facilities, 7,900 dialysis clinics, and 4,700 ambulatory surgery centers, and will extend to other outpatient settings.
“This funding will dramatically improve the safety and quality of the healthcare delivered in the United States during the pandemic and in the future,” said CDC Director Rochelle P. Walensky, M.D., M.P.H. “Funding will provide significant resources to our public health departments and healthcare systems and opportunities to develop innovative strategies to protect every segment of the U.S. population, especially those disproportionately affected by the pandemic, at a time that they are hit hard.”
Additionally, these investments will help address the rise of healthcare-associated infections, which increased as U.S. hospitals were inundated by COVID-19—reversing national progress seen prior to the pandemic.
Over the next 3 years, CDC will issue $1.25 billion of the total to 64 state, local, and territorial health departments to support this work. Initial awards totaling $885 million will be made in October 2021 to these jurisdictional health departments. CDC will use the majority of this initial funding in October, $500 million, to support a new force in the fight against COVID-19 to protect our most disproportionately affected population…
Next ACIP Meetings
No registration is required to watch the webcast.
:: September 22, 2021, 10:00 a.m. – 5:00 p.m. and September 23, 2021, 11:00 a.m. – 2:00 p.m. is a virtual COVID-19 meeting at https://video.ibm.com/channel/VWBXKBR8af4
No Agenda posted at inquiry.
:: September 29, 2021, 10:00 a.m. – 5:30 p.m. virtual meeting at https://video.ibm.com/channel/VWBXKBR8af4
Agenda draft: https://www.cdc.gov/vaccines/acip/meetings/downloads/agenda-archive/Draft_Meeting-Agenda_Sept-29-2021_for-posting-508.pdf
MMWR News Synopsis Friday, September 17, 2021
:: Disaggregating Data to Measure Racial Disparities in COVID-19 Outcomes and Guide Community Response — Hawaii, March 1, 2020–February 28, 2021
:: Longitudinal Trends in Body Mass Index Before and During the COVID-19 Pandemic Among Persons Aged 2–19 Years — United States, 2018–2020
:: Monitoring Incidence of COVID-19 Cases, Hospitalizations, and Deaths, by Vaccination Status — 13 U.S. Jurisdictions, April 4–July 17, 2021
:: Interim Estimates of COVID-19 Vaccine Effectiveness Against COVID-19–Associated Emergency Department or Urgent Care Clinic Encounters and Hospitalizations Among Adults During SARS-CoV-2 B.1.617.2 (Delta) Variant Predominance — Nine States, June–August 2021
:: Effectiveness of COVID-19 mRNA Vaccines Against COVID-19–Associated Hospitalization — Five Veterans Affairs Medical Centers, United States, February 1–August 6, 2021
:: New COVID-19 Cases and Hospitalizations Among Adults, by Vaccination Status — New York, May 3–July 25, 2021
Coronavirus Disease 2019 (COVID-19)– CDC
Approximately 25 announcements/reports/data summaries.
:: EARLY RELEASE: Comparative Effectiveness of Moderna, Pfizer-BioNTech, and Janssen (Johnson & Johnson) Vaccines in Preventing COVID-19 Hospitalizations Among Adults Without Immunocompromising Conditions — United States, March–August 2021
9/17/2021
Africa CDC [to 18 Sep 2021]
http://www.africacdc.org/
News
Press Releases
African Union and EDCTP sign Memorandum of Understanding to promote new paradigm in health
ADDIS ABABA, ETHIOPIA, and THE HAGUE, THE NETHERLANDS, September 14, 2021 – The African Union (AU) through the African Centres for Disease Control and Prevention (Africa CDC), and the European and Developing Countries Clinical Trials Partnership (EDCTP) have signed a Memorandum of Understanding (MoU) aimed at establishing a framework to serve as a firm basis for cooperation in their shared goals to promote a new paradigm in health.
Through the MoU, the Africa CDC and EDCTP express their commitment towards joining efforts and maintaining a close and continuous relationship for the achievement of their common objectives. The scope of the MoU is defined through the following themes: Emerging and re-emerging infectious diseases, epidemic intelligence and capacity building for preparedness and outbreak response. The MoU also covers implementation and public health research, the one health approach, and data management. AU and EDCTP will cooperate to implement a programme of work for the execution of activities within these themes.
“The COVID‐19 pandemic represents an unprecedented challenge to health systems, the economy and society across Africa. The partnership between Africa CDC and EDCTP will allow African Union Member States to build back better and stronger from the pandemic. It will take Member States a step closer to a strong and resilient health systems that can prevent, detect, and efficiently respond to infectious disease threats, wherever and whenever they may occur on the continent.” Dr John Nkengasong, Director of Africa CDC…
China CDC http://www.chinacdc.cn/en/
National Health Commission of the People’s Republic of China [to 18 Sep 2021]
http://en.nhc.gov.cn/
News
Sept 18: Daily briefing on novel coronavirus cases in China
On Sept 17, 31 provincial-level regions and the Xinjiang Production and Construction Corps on the Chinese mainland reported 46 new cases of confirmed infections.
China surpasses 1 billion fully vaccinated
2021-09-17
China’s Chongqing to vaccinate foreign minors against COVID-19
2021-09-17
HONGQING — Southwest China’s Chongqing Municipality will administer COVID-19 vaccines to foreigners aged 12 to 17 from Saturday on a voluntary basis, according to the Chongqing Foreign Affairs Office.
Foreign citizens who are covered by the local health insurance program will enjoy the same policy as insured Chinese people, and those not covered will be charged 100 yuan (about 15.5 U.S. dollars) per dose.
The vaccines are domestically-developed inactivated COVID-19 vaccines, and a total of one or two doses may be required subject to different vaccines…
National Medical Products Administration – PRC [to 18 Sep 2021]
http://english.nmpa.gov.cn/news.html
News
Over 2.16b doses of COVID-19 vaccines administered in China
2021-09-18
More than 2.16 billion doses of COVID-19 vaccines had been administered in China as of Thursday, data from the National Health Commission showed on Sept 17.
Premier Li stresses professional ethics among medical workers
2021-09-15
Premier Li Keqiang, also a member of the Standing Committee of the Political Bureau of the Communist Party of China Central Committee, presided over a medical expert symposium and listened to the attendees’ opinions and suggestions on the development and innovation of medical and health services during a visit to the Peking Union Medical College Hospital on Sept 13.
CCDC Weekly – Weekly Reports: Current Volume (3)
2021-09-17 / No. 38
PDF of this issue
:: Preplanned Studies: Outbreaks of Acute Respiratory Disease Associated with Human Adenovirus Infection in Closed Camps, China, December 2011–March 2014
:: Preplanned Studies: Malaria Surveillance of Entry People During the COVID-19 Epidemic — Guangdong Province, China, October 2020–May 2021
:: Preplanned Studies: Identifying the Key Nodes of HIV Molecular Transmission Network Among Men Who Have Sex with Men — Guangzhou, Guangdong Province, China, 2015–2017
:: Notes from the Field: Two Confirmed Patients of Anthrax — Binzhou City, Shandong Province, China, August 2021
:: Notes from the Field: HIV-2 Seroepidemiological Evidence in Hunan Province — China, 2003–2020
::::::
Organization Announcements
Editor’s Note:
Careful readers will note that the number and range of organizations now monitored in our Announcements section below has grown as the impacts of the pandemic have spread across global economies, supply chains and programmatic activity of multilateral agencies and INGOs.
Paul G. Allen Frontiers Group [to 18 Sep 2021]
https://alleninstitute.org/what-we-do/frontiers-group/news-press/
News
No new digest content identified.
BARDA – U.S. Department of HHS [to 18 Sep 2021]
https://www.phe.gov/about/barda/Pages/default.aspx
News
No new digest content identified.
BMGF – Gates Foundation [to 18 Sep 2021]
https://www.gatesfoundation.org/ideas/media-center
Press Releases and Statements
Gates Foundation’s Annual Goalkeepers Report Finds Stark Disparities in COVID-19 Impacts
New data reveals world stepped up to prevent worst-case scenarios from happening; spotlights need for long-term investments to ensure an equitable recovery and continued progress toward the Global Goals
SEATTLE (September 13, 2021) — The Bill & Melinda Gates Foundation today launched its fifth annual Goalkeepers Report, featuring an updated global dataset illustrating the pandemic’s adverse impact on progress toward the United Nations Sustainable Development Goals (Global Goals).
This year’s report, co-authored by Bill Gates and Melinda French Gates, co-chairs of the Bill & Melinda Gates Foundation, shows that disparities caused by COVID-19 remain stark, and those who have been hardest hit by the pandemic will be the slowest to recover. Because of COVID-19, an additional 31 million people were pushed into extreme poverty in 2020 compared to 2019. And while 90% of advanced economies will regain pre-pandemic per capita income levels by next year, only a third of low- and middle-income economies are expected to do so…
Bill & Melinda Gates Medical Research Institute [to 18 Sep 2021]
https://www.gatesmri.org/
The Bill & Melinda Gates Medical Research Institute is a non-profit biotech organization. Our mission is to develop products to fight malaria, tuberculosis, and diarrheal diseases—three major causes of mortality, poverty, and inequality in developing countries. The world has unprecedented scientific tools at its disposal; now is the time to use them to save the lives of the world’s poorest people
No new digest content identified.
CARB-X [to 18 Sep 2021]
https://carb-x.org/
News
No new digest content identified.
Center for Vaccine Ethics and Policy – GE2P2 Global Foundation [to 18 Sep 2021]
https://centerforvaccineethicsandpolicy.net/
News/Analysis/Statements
:: Past weekly editions and posting of all segments of Vaccines and Global Health: The Week in Review are available here.
:: [NEW] Informed Consent: A Monthly Review – September 2021 is now posted here
CEPI – Coalition for Epidemic Preparedness Innovations [to 18 Sep 2021]
http://cepi.net/
Latest News
Two expert health leaders join CEPI Board
September 16, 2021, Oslo, Norway– World-leading health experts Dr. Nísia Trindade Lima and Dr. Juan Pablo Uribe have been appointed to the Board of the Coalition for Epidemic Preparedness Innovations (CEPI), an international organisation working to rapidly advance vaccines against COVID-19 and other emerging infectious diseases, and enable access to these vaccines for people during outbreaks…
DARPA – Defense Advanced Research Projects Agency [to 18 Sep 2021
https://www.darpa.mil/news
News
No new digest content identified.
Duke Global Health Innovation Center [to 18 Sep 2021]
https://dukeghic.org/
Our Blog
No new digest content identified.
EDCTP [to 18 Sep 2021]
http://www.edctp.org/
The European & Developing Countries Clinical Trials Partnership (EDCTP) aims to accelerate the development of new or improved drugs, vaccines, microbicides and diagnostics against HIV/AIDS, tuberculosis and malaria as well as other poverty-related and neglected infectious diseases in sub-Saharan Africa, with a focus on phase II and III clinical trials
News
14 September 2021
African Union and EDCTP sign Memorandum of Understanding to promote new paradigm in health
The African Union (AU) through the African Centres for Disease Control and Prevention (Africa CDC), and the European and Developing Countries Clinical Trials Partnership (EDCTP) have signed a Memorandum of Understanding (MoU) aimed at establishing a framework to serve as a firm basis for cooperation in their shared goals to promote a new paradigm in health.
Through the MoU, the Africa CDC and EDCTP express their commitment towards joining efforts and maintaining a close and continuous relationship for the achievement of their common objectives. The scope of the MoU is defined through the following themes: Emerging and re-emerging infectious diseases, epidemic intelligence and capacity building for preparedness and outbreak response. The MoU also covers implementation and public health research, the one health approach, and data management. AU and EDCTP will cooperate to implement a programme of work for the execution of activities within these themes…
Emory Vaccine Center [to 18 Sep 2021]
http://www.vaccines.emory.edu/
Vaccine Center News
No new digest content identified.
European Vaccine Initiative [to 18 Sep 2021]
http://www.euvaccine.eu/
Latest News
No new digest content identified.
Fondation Merieux [to 18 Sep 2021]
http://www.fondation-merieux.org/
News, Events
No new digest content identified.
Gavi [to 18 Sep 2021]
https://www.gavi.org/
13 September 2021
Iraq receives first doses donated by Italy through COVAX
GHIT Fund [to 18 Sep 2021]
https://www.ghitfund.org/newsroom/press
GHIT was set up in 212 with the aim of developing new tools to tackle infectious diseases that
No new digest content identified.
Global Fund [to 18 Sep 2021]
https://www.theglobalfund.org/en/news/
News & Stories
News
No new digest content identified.
Global Research Collaboration for Infectious Disease Preparedness [GloPID-R] [to 18 Sep 2021]
https://www.glopid-r.org/news/
No new digest content identified.
Hilleman Laboratories [to 18 Sep 2021]
http://www.hillemanlabs.org/
Website reports “under maintenance” at inquiry
Human Vaccines Project [to 18 Sep 2021]
http://www.humanvaccinesproject.org/
News
HVP COVID Report
Sep 16, 2021
Flor Munoz: What is Driving a Surge in COVID Cases Among Children?
IAVI [to 18 Sep 2021]
https://www.iavi.org/newsroom
Latest News
No new digest content identified.
International Coalition of Medicines Regulatory Authorities [ICMRA]
http://www.icmra.info/drupal/en/news
Selected Statements, Press Releases, Research
No new digest content identified.
ICRC [to 18 Sep 2021]
https://www.icrc.org/en/whats-new
Selected News Releases, Statements, Reports
President Peter Maurer addresses the High-level Ministerial Meeting on the Humanitarian Situation in Afghanistan
Secretary-General Guterres, Excellencies,I have just returned from Afghanistan, where I met with the Taliban leadership and visited ICRC’s humanitarian operations, which have continued largely uninterrupted. Across the country, the magnitude of need i
13-09-2021 | Statement
IFFIm
http://www.iffim.org/
Press Releases/Announcements
No new digest content identified.
IFRC [to 18 Sep 2021]
http://media.ifrc.org/ifrc/news/press-releases/
Selected Press Releases, Announcements
More than 139 million people hit by climate crisis and COVID-19, new IFRC analysis reveals
13/09/2021
WHO/Europe and IFRC sign Memorandum of Understanding to help countries achieve health for all
13/09/2021
Institut Pasteur [to 18 Sep 2021]
https://www.pasteur.fr/en/press-area
Press Documents
No new digest content identified.
IOM / International Organization for Migration [to 18 Sep 2021]
http://www.iom.int/press-room/press-releases
News – Selected
No new digest content identified.
ISC / International Science Council [to 18 Sep 2021]
https://council.science/current/
ISC is a non-governmental organization with a unique global membership that brings together 40 international scientific Unions and Associations and over 140 national and regional scientific organizations including Academies and Research Councils.
News
Blog
How can we communicate science in a more inclusive and accessible manner?
17.09.2021
As part of the continuous workshop series by and for the ISC Science Communications Network, we gathered for an interactive session to discuss best practices in accessible and inclusive science communication. Watch the recordings, download the slides, and connect with the speakers…
IVAC [to 18 Sep 2021]
https://www.jhsph.edu/research/centers-and-institutes/ivac/index.html
Updates; Events
No new digest content identified.
IVI [to 18 Sep 2021]
http://www.ivi.int/
Selected IVI News, Announcements, Events
IVI’s 20th International Vaccinology Course brings virtual training to vaccine professionals and students across 155 countries
Johns Hopkins Center for Health Security [to 18 Sep 2021]
https://www.centerforhealthsecurity.org/news/center-news/
Center News
New Local Research Reports Released on Carrying Equity in COVID-19 Vaccination Forward
September 15, 2021
The CommuniVax Coalition, which is led by the Johns Hopkins Center for Health Security at the Bloomberg School of Public Health and the Department of Anthropology at Texas State University, released 4 new local reports that share findings from local rapid research within Black and Hispanic/Latino communities in Alabama, California, Idaho, and Maryland.
The new reports, produced by the local CommuniVax teams, highlight the urgent need to humanize delivery and communication strategies for COVID-19 vaccines, develop better and heterogenous messaging, and anchor COVID-19 vaccination efforts in hard-hit communities in a holistic “whole person” recovery process…
MSF/Médecins Sans Frontières [to 18 Sep 2021]
http://www.msf.org/
Latest [Selected Announcements]
Coronavirus COVID-19 pandemic
European Union: more empty promises about global COVID-19 vaccine equity
Project Update 15 Sep 2021
Niger
Combating malaria through water treatment for communities in Niger
Project Update 14 Sep 2021
… “The EU likes to portray itself as a champion of vaccine equity,” says Dr Christos Christou, president of Médecins Sans Frontières. “But the gap between those beautiful words and its actions is embarrassingly wide…
National Academy of Medicine – USA [to 18 Sep 2021]
https://nam.edu/programs/
Selected News/Programs
Risa Lavizzo-Mourey Receives Lienhard Award; Spero M. Manson Receives Sarnat Prize
September 15, 2021
Risa Lavizzo-Mourey Receives Lienhard Award From National Academy of Medicine for Leadership to Improve the Health of All Americans The National Academy of Medicine today announced Risa Lavizzo-Mourey is the recipient of the 2021 Gustav O. Lienhard Award for Advancement of Health Care for her unwavering efforts to improve the health of all Americans by […]
New Discussion Paper Urges Health Care Quality and Safety Initiatives to Center Health Equity
September 15, 2021
A new individually authored discussion paper in NAM Perspectives — the digital periodical of the National Academy of Medicine — published September 15, 2021 identifies health equity as the area of most urgent and cross-cutting concern for health care quality organizations and outlines a proposed agenda for centering equity in efforts moving forward. On the […]
National Academy of Medicine Announces 10 Emerging Leaders in Health and Medicine
September 14, 2021
The National Academy of Medicine (NAM) today announced the 2021 Emerging Leaders in Health and Medicine Scholars. These individuals are early- to mid-career professionals from a wide range of health-related fields, from emergency medicine and health economics to biomedical engineering and research and public health policy. The scholars are an essential part of a major […]
National Academy of Sciences – USA [to 18 Sep 2021]
http://www.nasonline.org/news-and-multimedia/
News
No new digest content identified.
National Vaccine Program Office – U.S. HHS [to 18 Sep 2021]
https://www.hhs.gov/vaccines/about/index.html
Upcoming Meetings/Latest Updates
No new digest content identified.
NIH [to 18 Sep 2021]
http://www.nih.gov/news-events/news-releases
News Releases
NIH builds large nationwide study population of tens of thousands to support research on long-term effects of COVID-19
September 15, 2021 — NIH launched the RECOVER Initiative to learn why some people have prolonged symptoms or develop new or returning symptoms after the acute phase of infection from SARS-CoV-2.
PATH [to 18 Sep 2021]
https://www.path.org/media-center/
Press Releases
Levis Nderitu joins PATH as first Global Diversity, Equity and Inclusion Director
September 12, 2021 by PATH
PATH is happy to announce that Levis Nderitu is joining PATH as Director, Global Diversity, Equity, and Inclusion. Based in Nairobi, Kenya, Levis will refine the DEI Strategy PATH launched earlier this year and create a DEI center of expertise to advise, support, and bring together global workstreams.
Levis has over 10 years of international development and private sector experience in DEI, culture, and employee engagement across East Africa, Europe, and the United States. Most recently his work at Médecins Sans Frontières in Kenya has included developing a DEI vision and roadmap, serving as an advisor to leadership, facilitating difficult conversations, and training on cross-cultural competence, unconscious bias, and anti-racism…
Sabin Vaccine Institute [to 18 Sep 2021]
http://www.sabin.org/updates/pressreleases
Statements and Press Releases
No new digest content identified.
UNAIDS [to 18 Sep 2021]
http://www.unaids.org/en
Selected Press Releases/Reports/Statements
17 September 2021
Forty years of campaigning for equal access to life-saving medicines
15 September 2021
Community-led projects reach vulnerable populations in Latin America and the Caribbean
14 September 2021
More than 140 former heads of state and Nobel laureates call on candidates for German chancellor to waive intellectual property rules for COVID vaccines
14 September 2021
Community-based organizations call for scaled up Internet-based HIV prevention services in China
13 September 2021
Decline in new HIV infections has stalled
UNHCR Office of the United Nations High Commissioner for Refugees [to 18 Sep 2021]
http://www.unhcr.org/en-us/media-centre.htmlS
Selected News Releases, Announcements
UNHCR warns of dire consequences for refugees from COVID-19 underfunding
17 September 2021 |
[See Milestones above for detail]
UNICEF [to 18 Sep 2021]
https://www.unicef.org/media/press-releases
Press Releases, News Notes, Statements [Selected]
Press release
09/17/2021
Schoolchildren worldwide have lost 1.8 trillion hours and counting of in-person learning due to COVID-19 lockdowns, says UNICEF
Urging governments to reopen schools as soon as possible, UNICEF unveils No Time to Lose – a clock counting hours of lost learning – as the UN General Assembly gets underway in NY
Press release
09/15/2021
Indonesia: After 18 months of school closures, children must safely resume face-to-face learning as soon as possible – UNICEF/WHO
Students and teachers will need a full range of support to help catch up on lost learning
Press release
09/14/2021
One month after Haiti earthquake: 260,000 children still need humanitarian assistance – UNICEF
Unitaid [to 18 Sep 2021]
https://unitaid.org/
Featured News
15 September 2021
A new initiative will deliver enhanced malaria prevention to children under two across Africa through a WHO-recommended but under-implemented intervention
15 September 2021
Community health workers bring malaria prevention to pregnant women across Africa, and build new entry points to vital services
Vaccine Equity Cooperative [nee Initiative] [to 18 Sep 2021]
https://vaccineequitycooperative.org/news/
News
Sep 14, 2021
Media: Community-led efforts are the key to ending this pandemic
This article by Advisory Group member Dr. Alexandre White outlines how community-led responses to vaccination and health care delivery are the solution to the ongoing issues of COVID-19 vaccine access and hesitancy – and
Vaccination Acceptance & Demand Initiative [Sabin) [to 18 Sep 2021]
https://www.vaccineacceptance.org/
Announcements
No new digest content identified.
Vaccine Confidence Project [to 18 Sep 2021]
http://www.vaccineconfidence.org/
News, Research and Reports
Coronavirus global impact
Launched April 2, 2020 and recurring every 3 days, Premise Data is utilizing its global network of Contributors to assess economic, social, and health sentiment surrounding the coronavirus (COVID-19).
Vaccine Education Center – Children’s Hospital of Philadelphia [to 18 Sep 2021]
http://www.chop.edu/centers-programs/vaccine-education-center
News
No new digest content identified.
Wellcome Trust [to 18 Sep 2021]
https://wellcome.ac.uk/news
News and reports
Explainer
Author Josie Golding
How the response to Ebola outbreaks shows why we need to prioritise preparedness
16 September 2021
Explainer
How science is combatting infectious disease
15 September 2021
Explainer
The cost of not preparing for infectious diseases
12 September 2021
The Wistar Institute [to 18 Sep 2021]
https://www.wistar.org/news/press-releases
Press Releases
No new digest content identified.
WFPHA: World Federation of Public Health Associations [to 18 Sep 2021]
https://www.wfpha.org/
Latest News
In Solidarity with Afghanistan
Sep 14, 2021
Afghanistan is suffering a double burden of disease because communicable diseases are widely prevalent throughout the country and non-communicable diseases are also on the rise. Considering the recent changes in…
World Bank [to 18 Sep 2021]
http://www.worldbank.org/en/news/all
Selected News, Announcements
Infographic: A Policy Package to Promote Literacy for All Children
Date: September 17, 2021 Type: Infographic
World Bank Group to Discontinue Doing Business Report
WASHINGTON, September 16, 2021—The World Bank Group today issued the following statement on the Doing Business report:
“Trust in the research of the World Bank Group is vital. World Bank Group research informs the actions of policymakers, helps countries make better-informed decisions, and allows stakeholders to measure economic and social improvements more accurately. Such research has also been a valuable tool for the private sector, civil society, academia, journalists, and others, broadening understanding of global issues.
“After data irregularities on Doing Business 2018 and 2020 were reported internally in June 2020, World Bank management paused the next Doing Business report and initiated a series of reviews and audits of the report and its methodology. In addition, because the internal reports raised ethical matters, including the conduct of former Board officials as well as current and/or former Bank staff, management reported the allegations to the Bank’s appropriate internal accountability mechanisms.
“ After reviewing all the information available to date on Doing Business, including the findings of past reviews, audits, and the report the Bank released today on behalf of the Board of Executive Directors, World Bank Group management has taken the decision to discontinue the Doing Business report. The World Bank Group remains firmly committed to advancing the role of the private sector in development and providing support to governments to design the regulatory environment that supports this. Going forward, we will be working on a new approach to assessing the business and investment climate. We are deeply grateful to the efforts of the many staff members who have worked diligently to advance the business climate agenda, and we look forward to harnessing their energies and abilities in new ways.”
Statement on Release of Investigation into Data Irregularities in Doing Business 2018 and 2020
WASHINGTON, September 16, 2021— WASHINGTON, September 16, 2021—The World Bank Group today released the following statement on behalf of the Bank’s Board of Executive Directors:
“The World Bank’s Board of Executive Directors today authorized the release of “Investigation of Data Irregularities in Doing Business 2018 and Doing Business 2020 – Investigation Findings and Report to the Board of Executive Directors,” an independent external review of the facts and circumstances around previously reported data irregularities in the 2018 and 2020 Doing Business reports.”
Date: September 16, 2021 Type: Statement
[See Milestones above for detail]
International Organizations, Manufacturers Agree to Intensify Cooperation to Deliver COVID-19 Vaccines
Fourth Meeting of the Multilateral Leaders Task Force on Scaling COVID-19 Tools WASHINGTON, 16 September 2021—The heads of the International Monetary Fund, World Bank Group, World Health Organization and…
Date: September 16, 2021 Type: Statement
Climate Change Could Force 216 Million People to Migrate Within Their Own Countries by 2050
Decisive collective action could reduce climate migration by as much as 80 percent WASHINGTON, Sept. 13, 2021—The World Bank’s updated Groundswell report released today finds that climate change, an increasingly…
Date: September 13, 2021 Type: Press Release
World Customs Organization – WCO [to 18 Sep 2021]
http://www.wcoomd.org/
Latest News – Selected Items
17 September 2021
WCO addresses the Annual Meeting of International Organizations on “Facing Global Crises Together”
On 13 and 14 September 2021, the Organisation for Economic Co-operation and Development (OECD) and the United Nations Commission on International Trade Law (UNCITRAL) hosted online the 8th Annual Meeting of the Partnership for International Organisations. The event brought together 23 Leaders of International Organizations (IOs), including the WCO, represented by its Secretary General, Dr. Kunio Mikuriya, as well as government, academia and civil society representatives to discuss the theme of “Facing Global Crises for Better International Rulemaking” in view of helping governments strengthen, share and improve the international rules that frame our economies, societies and environment…
16 September 2021
The WCO kicks off regional consultations on the next Strategic Plan
World Organisation for Animal Health (OIE) [to 18 Sep 2021]
https://www.oie.int/en/for-the-media/press-releases/2021/
Press Releases, Statements
No new digest content identified.
WTO – World Trade Organisation [to 18 Sep 2021]
http://www.wto.org/english/news_e/news_e.htm
WTO News and Events
The fourth South-South Dialogue on LDCs and Development: Reinforcing the multilateral trading system for development
17 September 2021
Keynote address by DG Okonjo-Iweala
Speech
DG Okonjo-Iweala calls on WTO members to deliver tangible outcomes for LDCs at MC12
17 September 2021
Delivering results at the 12th Ministerial Conference (MC12) to enable least-developed countries (LDCs) to become more resilient and more integrated into the global economy is critical for meeting sustainable development goals, Director-General Ngozi Okonjo-Iweala told Geneva-based ambassadors from LDCs on 16-17 September in Montreux, Switzerland. DG Okonjo-Iweala was speaking at the South-South Dialogue on LDCs and Development sponsored by China.
International organizations, vaccine manufacturers agree to intensify cooperation to deliver COVID-19 vaccines
16 September 2021
The heads of the International Monetary Fund, World Bank Group, World Health Organization and World Trade Organization met with the CEOs of leading vaccine manufacturing companies to discuss strategies to improve access to COVID-19 vaccines, especially in low— and lower middle-income countries and in Africa. The Task Force expressed concerns that without urgent steps the world is unlikely to achieve the end-2021 target of vaccinating at least 40% of the population in all countries — a critical milestone to end the pandemic and for global economic recovery
[See Milestones above for detail]
::::::
ARM [Alliance for Regenerative Medicine] [to 18 Sep 2021]
Press Releases – Alliance for Regenerative Medicine (alliancerm.org)
Selected Press Releases
No new digest content identified.
BIO [to 18 Sep 2021]
https://www.bio.org/press-releases
Press Releases, Letters, Testimony, Comments [Selected]
No new digest content identified.
DCVMN – Developing Country Vaccine Manufacturers Network [to 18 Sep 2021]
http://www.dcvmn.org/
News; Upcoming events
No new digest content identified.
ICBA – International Council of Biotechnology Associations [to 18 Sep 2021]
https://internationalbiotech.org/news/
News
No new digest content identified.
IFPMA [to 18 Sep 2021]
http://www.ifpma.org/resources/news-releases/
Selected Press Releases, Statements, Publications
Meet Africa’s New Generation of Health Innovators
16 September 2021
IFPMA and Speak Up Africa announce winners of Africa Young Innovators for Health Award
13 September 2021
Report of the Pan-European Commission on Health and Sustainable Development at the WHO EURO 71st
13 September 2021
The International Federation of Pharmaceutical Manufacturers and Associations (IFPMA) and the European Federation of Pharmaceutical Industries and Associations (EFPIA) are pleased to contribute this statement to the 71st WHO Regional Committee meeting for Europe. EFPIA and IFPMA represent Europe’s and the world’s leading research-based biopharmaceutical companies, as well as national and regional industry associations, respectively.
COVID-19 has had profound health, social, and economic impacts across Europe and around the world. Coordinated, inclusive, and multi-stakeholder action is the only possible solution to mitigate the devastating consequences of this unprecedented global health emergency.
Innovative health industries remain at the forefront of the global effort to develop and manufacture tests, therapeutics, and vaccines to contain and defeat COVID-19. The existing IP framework has enabled the pharmaceutical industry to respond swiftly to the global crisis and develop several new vaccines with remarkable speed, by engaging in new collaborations to leverage both new approaches and existing molecules.
After more than 200 clinical trials and nearly 300 partnerships and collaborations among manufacturers worldwide, COVID-19 vaccine production has increased exponentially from zero to 5.8 billion doses by the end of August, 20% of which produced in Europe. In Europe 543,129,344 doses have been administered to citizens, equating to around 70% of the population. Globally, the industry is on target to deliver an astounding estimate of 12 billion doses by the end of 2021 – enough doses to vaccinate the world’s adult population. That said, COVID-19 vaccines are not equally reaching all priority populations worldwide. Access to COVID-19 related health products is a collective responsibility that calls for global solidarity and coordinated and collaborative action by public and private actors alike.
The innovative vaccine manufacturers and biotech companies have supported fair and equitable access to vaccines from the outset of the pandemic, as full and active partners in the ACT-Accelerator.
In this spirit, these companies represented by seven industry bodies, announced in May 2021 the “Five steps to urgently advance COVID-19 vaccine equity.” They commit to working with governments and non-governmental organizations including COVAX, CEPI, and WTO to support stepping up dose sharing, continue efforts to optimize production, call out trade barriers to be eliminated, support country readiness, and continue driving innovation.
Looking to the future, it is important that the world uses the lessons we have learned during the COVID-19 crisis to make sure we are all better prepared and have the capacity to respond to emergent health threats. With the creation of a European Health Emergency and Preparedness Response Authority (HERA), Europe is stepping in the right direction.
We call upon governments to do their part and ensure adequate resources are dedicated to building strong, resilient, and sustainable healthcare systems, supported by WHO EURO and other multilateral organizations, and that health is valued as an investment to ensure growth and prosperity. This would include strengthening prevention, early detection and interception of disease, implementing integrated and patient-centered care models, utilizing digital health and health data to its full potential, and increasing access to innovation that improves people’s health and enhances the efficiency of health systems. We also urge governments to guarantee immediate and unhindered access to pathogens and associated information regarding any COVID-19 variants to support the development of new vaccines and treatments.
Industry is committed to delivering preparedness solutions and to contributing our expertise to relevant discussions with national, regional, and global public health, diseases control and regulatory agencies, and to contribute to resilient and sustainable health systems in partnership with all stakeholders. We look forward to playing a meaningful role in shaping the future so that we are stronger together for the next health emergency.
International Generic and Biosimilar Medicines Association [IGBA]
https://www.igbamedicines.org/
News
No new digest content identified.
International Alliance of Patients’ Organizations – IAPO [to 18 Sep 2021]
https://www.iapo.org.uk/news/topic/6
Press and media [Selected]
No new digest content identified.
PhRMA [to 18 Sep 2021]
http://www.phrma.org/
Latest News [Selected]
America’s biopharmaceutical companies to Congress: Government “negotiation” is the wrong approach
September 15, 2021
We agree with leaders in Washington that Americans need help with their health care costs, but these dangerous policy experiments are not the answer.
Blog Post
Journal Watch
Vaccines and Global Health: The Week in Review continues its weekly scanning of key peer-reviewed journals to identify and cite articles, commentary and editorials, books reviews and other content supporting our focu-s on vaccine ethics and policy. Journal Watch is not intended to be exhaustive, but indicative of themes and issues the Center is actively tracking. We selectively provide full text of some editorial and comment articles that are specifically relevant to our work. Successful access to some of the links provided may require subscription or other access arrangement unique to the publisher.
If you would like to suggest other journal titles to include in this service, please contact David Curry at: david.r.curry@centerforvaccineethicsandpolicy.org
BMC Infectious Diseases
http://www.biomedcentral.com/bmcinfectdis/content
(Accessed 18 Sep 2021)
First description of immune complex vasculitis after COVID-19 vaccination with BNT162b2: a case report
Cases of immune complex vasculitis have been reported following COVID-19 infections; so far none in association with novel mRNA-based COVID-19 vaccination. This case report describes a cutaneous immune complex…
Authors: Victoria Therese Mücke, Viola Knop, Marcus Maximilian Mücke, Falk Ochsendorf and Stefan Zeuzem
Citation: BMC Infectious Diseases 2021 21:958
Content type: Case report
Published on: 16 September 2021
BMC Pregnancy and Childbirth
http://www.biomedcentral.com/bmcpregnancychildbirth/content
(Accessed 18 Sep 2021)
COVID-19 mRNA vaccine and antibody response in lactating women: a prospective cohort study
Immunological protection via breastfeeding is well known. The immunological profile of human milk changes during lactation. No clinical trials have been conducted in lactating women with the newest mRNA vaccin…
Authors: Nadia Charepe, Juliana Gonçalves, A. Margarida Juliano, David G. Lopes, Helena Canhão, Helena Soares and e Fátima Serrano
Citation: BMC Pregnancy and Childbirth 2021 21:632
Content type: Research
Published on: 17 September 2021
BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 18 Sep 2021)
Vaccine hesitancy: evidence from an adverse events following immunization database, and the role of cognitive biases
Vaccine hesitancy has been a growing challenge for public health in recent decades. Among factors contributing to vaccine hesitancy, concerns regarding vaccine safety and Adverse Events (AEs) play the leading …
Authors: Hossein Azarpanah, Mohsen Farhadloo, Rustam Vahidov and Louise Pilote
Citation: BMC Public Health 2021 21:1686
Content type: Research
Published on: 16 September 2021
BMC Research Notes
http://www.biomedcentral.com/bmcresnotes/content
(Accessed 18 Sep 2021)
Changes in patients’ outlook, behaviors, and attitudes toward COVID-19 after hospitalization and their experiences of discrimination and harassment
This study aims to examine changes in patients’ perspectives and outlooks regarding the disease and their health after hospitalization for COVID-19 and investigate their discrimination and harassment experienc…
Authors: Ken Goda, Tsuneaki Kenzaka, Shinsuke Yahata, Ayako Kumabe, Masahiro Katsurada and Hogara Nishisaki
Citation: BMC Research Notes 2021 14:362
Content type: Research note
Published on: 17 September 2021
Cell
Sep 16, 2021 Volume 184 Issue 19 p4841-5070
https://www.cell.com/cell/current
Reviews
The origins of SARS-CoV-2: A critical review
Edward C. Holmes,et al/
Open Access
A review of the current literature supports a zoonotic origin for SARS-CoV-2 and emphasizes the need to focus on identifying the exact animal host through collaborative and carefully coordinated studies. This will enable the community to understand the roots of the COVID-19 pandemic as well as better prepare us for future pandemics
Cell
Sep 16, 2021 Volume 184 Issue 19 p4841-5070
https://www.cell.com/cell/current
Articles
Emergence of an early SARS-CoV-2 epidemic in the United States
Mark Zeller,wt al.
Genomic and epidemiological analyses provide a clearer picture of one of the earliest SARS-CoV-2 superspreader events in the United States in accelerating transmission, with a single introduction of the virus being responsible for most cases during this period.
Clinical Therapeutics
June 2021 Volume 43 Issue 6 p917-1134
http://www.clinicaltherapeutics.com/current
Commentaries
SARS-CoV-2 Monoclonal Antibodies in Children: Ethical Considerations
Ian D. Wolfe, Sameer J. Patel
Published online: May 06, 2021
e157-e162
Abstract
The use of monoclonal antibodies in children with certain conditions and at high risk for severe COVID-19 has been approved by the US Food and Drug Administration under the Emergency Use Authorization mechanism of the Federal Food, Drug, and Cosmetic Act. No data on the tolerability or efficacy of these therapies in persons <18 years of age are available; there is risk. Whether they will work is unknown, but they could. A disproportionate number of these children who meet the criteria for treatment with mAbs are from communities of black, Native American, and other race. How should health systems, hospitals, and clinicians balance the tensions between being seen as experimenting with an untested drug as opposed to withholding a potentially life-saving treatment? This article identifies, analyzes, and makes recommendations on the methods by which health systems, hospitals, and individual clinicians can ethically balance these tensions.
Clinical Therapeutics
June 2021 Volume 43 Issue 6 p917-1134
http://www.clinicaltherapeutics.com/current
Exploration and Ethical Analysis of Open-label Pediatric Vaccine Trials in a Pandemic
Ian D. Wolfe, Angira Patel, Larry K. Kociolek, Asma Fazal, Ravi Jhaveri, John D. Lantos
Published online: May 23, 2021
e163-e172
Abstract
Young children will ultimately need to be vaccinated to stop the spread of coronavirus disease 2019 (COVID-19). Initial studies of vaccine were performed in adults. Randomized controlled trials are the gold standard. In the COVID-19 pandemic, many questions need to be answered about the ethics and feasibility of these trials. Given the harms of the COVID-19 pandemic and the now-known efficacy of the vaccines in adults and teens, the question of whether clinical equipoise exists for a placebo-controlled trial of vaccines in younger children remains. Parents may be reluctant to enroll children in these trials because they want their child to receive the vaccine or because they are worried about vaccines or clinical trials in general. One option for gathering data on tolerability and efficacy in children would be to use a nonrandomized trial to enroll parents willing to vaccinate their children and those who are hesitant. We discuss the advantages and disadvantages of such an open-label trial that could provide guidance for future pandemics.
Conflict and Health
http://www.conflictandhealth.com/
[Accessed 18 Sep 2021]
Sanctioned countries in the global COVID-19 vaccination campaign: the forgotten 70%
Authors: Karl Blanchet, Grégoire Mallard, Erica Moret and Jin Sun
Content type: Commentary
17 September 2021
Abstract
COVAX, the global initiative on COVID-19 vaccines, has set the target of achieving a COVID-19 vaccination coverage of up to 30% of the population of 135 countries in 2 years. Here, we argue that COVAX should anticipate important and unforeseen challenges with regard to sanctioned countries. For those, COVAX needs to provide a higher percentage of the vaccines. Otherwise, the problems of vaccination will linger, risking the advent of new variants and preventing an effective global response in reigning the pandemic under control.
EMBO Reports
Volume 22 Issue 9 6 September 2021
https://www.embopress.org/toc/14693178/current
Science & Society 4 August 2021 Open Access
The viral era: New biotechnologies give humans an unprecedented control over Nature and require appropriate safeguards
Bernd Giese
New biotechnologies such as gene drives and engineered viruses herald a viral era that would give humans exceptional power over any organism at the level of the genotype.
Emerging Infectious Diseases
Volume 27, Number 9—September 2021
http://wwwnc.cdc.gov/eid/
Expedited Articles
Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy
A. Baj et al.
Ethics & Human Research
Volume 43, Issue 5 Pages: 1-44 September–October 2021
https://onlinelibrary.wiley.com/toc/25782363/current
Commentary
Free Access
A Call for Better, Not Faster, Research Ethics Committee Reviews in the Covid-19 Era
Leonardo Tamariz, Fred J. Hendler, John M. Wells, Annette Anderson, Stephen Bartlett
Pages: 42-44
First Published: 08 September 2021
Ethics & International Affairs
Summer 2021 (35.2) August 2021
https://www.ethicsandinternationalaffairs.org/2021/spring-2021-35-1/
The editors of Ethics & International Affairs are pleased to present the Summer 2021 issue of the journal! The highlight of this issue is a roundtable organized by Adrian Gallagher on the responsibility to protect in a changing world order. The roundtable contains an introductory essay by Michael Ignatieff and contributions from Adrian Gallagher and Nicholas J. Wheeler; Cristina G. Stefan; Luke Glanville and James Pattison; and Jennifer M. Welsh. Additionally, the issue includes feature articles by Daniele Amoroso and Guglielmo Tamburrini on meaningful human control over weapons systems and Patricia Goff on inclusive trade. It also contains a review essay by Andrea C. Simonelli on climate displacement and justice and book reviews by Reed Bonadonna, Cian O’Driscoll, and Shelley Wilcox.
Ethics & International Affairs
Summer 2021 (35.2) August 2021
https://www.ethicsandinternationalaffairs.org/2021/spring-2021-35-1/
Equity and Vaccine Allocation: Beyond Ethics in Prioritization to Equitable Production, Distribution, and Consumption
Nicole Hassoun | July 2021
Conclusion
Ethicists interested in equitable international vaccine allocation have traditionally focused on principles for prioritizing patient populations, but to have the greatest health impact—whether one focuses on lives, life years, or something else—we must change the question. We should ask how we can vaccinate everyone most effectively. We need to address the need for adequate manufacturing and distribution systems, health care workers, funding, trust in science, and community engagement. We must rethink how we support research and development and reward pharmaceutical innovation to fairly address the COVID-19 pandemic and many other major global health problems. Doing so will in the long run protect individuals better than merely shifting resources around as several current proposals for equitable allocation suggest. It is also in the best interest of some of the world’s wealthiest countries to help develop basic health systems in countries that lack them and reconsider incentives for new pharmaceutical research and development. We need to foster global solidarity to overcome ongoing pandemics and to prepare for those that will surely come our way. We must do more to ensure that poor countries are not left behind. We should institute basic global health systems and support efforts to research, manufacture, distribute, and help everyone access vaccines and other essential medicines for COVID-19 and other major global health problems.51 Anything less is inequitable.52
The European Journal of Public Health
SUPPLEMENT – Volume 31, Issue Supplement_1, July 2021
https://academic.oup.com/eurpub/issue/31/Supplement_1
Supplement: E-Mental-Health: Exploring the Evidence Base and Stakeholders’ Perspectives on Internet-Based Interventions for the Prevention of Mental Health Conditions
Mental illness represents an enormous personal, social and societal burden for European citizens1 calling for the need to expand existing models of mental healthcare delivery. In Europe, the Internet is a key source of health information,2 and technology-enhanced (psychological) interventions such as Internet- and mobile-delivered applications (‘eHealth’3 and ‘m-Health’4) have become increasingly popular and studied. There is already strong evidence of the efficacy of online interventions for the prevention and treatment of several psychological disorders5,6 and meta-analyses show effect sizes similar to face-to-face interventions.7
Gates Open Research
https://gatesopenresearch.org/browse/articles
[Accessed 18 Sep 2021]
Research Article metrics AWAITING PEER REVIEW
Integration of HIV and sexual and reproductive health in the era of anti-retroviral-based prevention: findings from assessments in Kenya, Malawi and Zimbabwe [version 1; peer review: awaiting peer review]
Fannie Kachale, Imelda Mahaka, Fatima Mhuriro, Mary Mugambi, Joseph Murungu, Barbra Ncube, Getrude Ncube, Albert Ndwiga, Rose Nyirenda, Violet Otindo, Anna Carter, Megan Dunbar, Janet Fleischman, Jessica Rodrigues, Kate Segal
Peer Reviewers Invited
Funder Bill and Melinda Gates Foundation
PUBLISHED 15 Sep 2021
Globalization and Health
http://www.globalizationandhealth.com/
[Accessed 18 Sep 2021]
The Global Fund: why anti-corruption, transparency and accountability matter
Authors: Zhihao Chang, Violet Rusu and Jillian C. Kohler
Content type: Research
18 September 2021
Background
The creation of the Global Fund to Fight AIDS, Tuberculosis and Malaria, also known as the Global Fund, was prompted by the lack of a timely and effective global response, and the need for financing to fight against three devastating diseases: HIV/AIDS, tuberculosis, and malaria. During the formation of the Global Fund, necessary anti-corruption, transparency, and accountability (ACTA) structures were not put in place to prevent fraud and corruption in its grants, which resulted in the misuse of funds by grant recipients and an eventual loss of donor confidence in 2011. The Global Fund has instituted various ACTA mechanisms to address this misuse of funding and the subsequent loss of donor confidence, and this paper seeks to understand these implementations and their impacts over the past decade, in an effort to probe ACTA more deeply.
Globalization and Health
http://www.globalizationandhealth.com/
[Accessed 18 Sep 2021]
De-escalation strategies for non-pharmaceutical interventions following infectious disease outbreaks: a rapid review and a proposed dynamic de-escalation framework
Authors: Charbel El Bcheraoui, Sophie Alice Müller, Eleanor C Vaughan, Andreas Jansen, Robert Cook and Johanna Hanefeld
Content type: Research
16 September 2021
Health Policy and Planning
Volume 36, Issue 8, October 2021
https://academic.oup.com/heapol/issue/36/8
ORIGINAL ARTICLES
The incremental cost of improving immunization coverage in India through the Intensified Mission Indradhanush programme
Susmita Chatterjee, Palash Das, Anita Pinheiro, Pradeep Haldar, Arindam Ray …
Health Policy and Planning, Volume 36, Issue 8, October 2021, Pages 1316–1324, https://doi.org/10.1093/heapol/czab053
Humanitarian Exchange Magazine
Number 79, May 2021
https://odihpn.org/magazine/localisation-and-local-humanitarian-action/
Localisation and local humanitarian action
by HPN October 2020
The theme of this edition of Humanitarian Exchange is localisation+ and local humanitarian action. Five years ago this week, donors, United Nations (UN) agencies, non-governmental organisations (NGOs), the International Committee of the Red Cross (ICRC) and International Federation of Red Cross and Red Crescent Societies (IFRC) committed within the Grand Bargain to increase multi-year investments in the institutional capacities of local and national responders, and to provide at least 25% of humanitarian funding to them as directly as possible. Since then, there is increasing consensus at policy and normative level, underscored by the Covid-19 pandemic, that local leadership should be supported. Localisation has gone from a fringe conversation among policy-makers and aid agencies in 2016 to a formal priority under the Grand Bargain. Wider global movements on anti-racism and decolonisation have also brought new momentum to critical reflections on where power, knowledge and capacity reside in the humanitarian system. Yet progress has been slow and major gaps remain between the rhetoric around humanitarian partnerships, funding and coordination and practices on the ground.
Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 10, 2021
https://www.tandfonline.com/toc/khvi20/current
Article Commentary
Likelihood of COVID-19 vaccination by subgroups across the US: post-election trends and disparities
Peter G. Szilagyi, Kyla Thomas, Megha D. Shah, Nathalie Vizueta, Yan Cui, Sitaram Vangala & Arie Kapteyn
Pages: 3262-3267
Published online: 25 Jun 2021
Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 10, 2021
https://www.tandfonline.com/toc/khvi20/current
Mini-Review
Landscape and progress of global COVID-19 vaccine development
Hui-Yao Huang, Shu-Hang Wang, Yu Tang, Wei Sheng, Chi-Jian Zuo, Da-Wei Wu, Hong Fang, Qiong Du & Ning Li
Pages: 3276-3280
Published online: 13 Jul 2021
Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 10, 2021
https://www.tandfonline.com/toc/khvi20/current
Review
Early approval of COVID-19 vaccines: Pros and cons
Md Arifur Rahman & Md Sayeedul Islam
Pages: 3288-3296
Published online: 20 Jul 2021
Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 10, 2021
https://www.tandfonline.com/toc/khvi20/current
Article
A case control study to assess effectiveness of measles containing vaccines in preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children
Nilesh Gujar, Muralidhar Tambe, Malangori Parande, Nandkumar Salunke, Ganesh Jagdale, Sarah G. Anderson, Abhijeet Dharmadhikari, Anand Lakhkar & Prasad S. Kulkarni
Pages: 3316-3321
Published online: 15 Jun 2021
Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 10, 2021
https://www.tandfonline.com/toc/khvi20/current
Article
Acceptability of COVID-19 vaccination in Saudi Arabia: A cross-sectional study using a web-based survey
Saeed Mastour Alshahrani, Salem Dehom, Diaa Almutairi, Badr Saud Alnasser, Bandar Alsaif, Ahmed A. Alabdrabalnabi, Abdullah Bin Rahmah, Mastour Safar Alshahrani, Ashraf El-Metwally, Badr F Al-Khateeb, Fatmah Othman & Mohammad Mahtab Alam
Pages: 3338-3347
Published online: 08 Jul 2021
Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 10, 2021
https://www.tandfonline.com/toc/khvi20/current
Article
COVID-19 vaccine hesitancy: a survey in a population highly compliant to common vaccinations
Flora Fedele, Massimo Aria, Valeria Esposito, Maria Micillo, Gaetano Cecere, Maria Spano & Giulio De Marco
Pages: 3348-3354
Published online: 07 Jun 2021
Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 10, 2021
https://www.tandfonline.com/toc/khvi20/current
Article
Factors influencing COVID-19 vaccine hesitancy and acceptance among the Pakistani population
Farooq Ahmad Chaudhary, Basaruddin Ahmad, Muhammad Danial Khalid, Ayesha Fazal, Muhammad Mohsin Javaid & Danial Qasim Butt
Pages: 3365-3370
Published online: 08 Jul 2021
Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 10, 2021
https://www.tandfonline.com/toc/khvi20/current
Article
Quality over quantity: human papillomavirus vaccine information on social media and associations with adult and child vaccination
Annalynn M. Galvin, Ashvita Garg, Jonathan D. Moore, Dana M. Litt & Erika L. Thompson
Pages: 3587-3594
Published online: 04 Jun 2021
Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 10, 2021
https://www.tandfonline.com/toc/khvi20/current
Review
15-year experience with rotavirus vaccination in Mexico: a systematic literature review
Adriana Guzman-Holst, Eduardo Ortega-Barria, Ángel Alexis Flores, Roberto Carreño-Manjarrez, Dagna Constenla & Maria Yolanda Cervantes-Apolinar
Pages: 3623-3637
Published online: 30 Jun 2021
Infectious Diseases of Poverty
http://www.idpjournal.com/content
[Accessed 18 Sep 2021]
Measuring COVID-19 vaccination coverage: an enhanced age-adjusted two-step floating catchment area model
Authors: Alireza Mohammadi, Abolfazl Mollalo, Robert Bergquist and Behzad Kiani
Content type: Research Article
16 September 2021
JAMA
September 14, 2021, Vol 326, No. 10, Pages 889-984
https://jamanetwork.com/journals/jama/currentissue
Research Letter
Trends in Mortality From COVID-19 and Other Leading Causes of Death Among Latino vs White Individuals in Los Angeles County, 2011-2020
Paul Simon, MD; Alex Ho, MD; Megha D. Shah, MD; et al.
free access has active quiz
JAMA. 2021;326(10):973-974. doi:10.1001/jama.2021.11945
This study compares age-adjusted mortality rates before and during the COVID-19 pandemic (2011-2020) among Latino and White individuals living in Los Angeles County.
JAMA
September 14, 2021, Vol 326, No. 10, Pages 889-984
https://jamanetwork.com/journals/jama/currentissue
Viewpoint
Making Vaccines Available to Other Countries Before Offering Domestic Booster Vaccinations
G. Owen Schaefer, DPhil; R. J. Leland, PhD; Ezekiel J. Emanuel, MD, PhD
free access
JAMA. 2021;326(10):903-904. doi:10.1001/jama.2021.13226
This Viewpoint highlights countries with higher concentrations of COVID-19–vaccinated residents and and excess vaccine supply vs those without, and it emphasizes the clinical and ethical reasons for prioritizing distribution of excess vaccine to underserved countries instead of keeping it for booster administration.
vaccines and global health :: ethics and policy 