Nature Reviews Immunology
February 2017 Vol 17 No 2
Disease tolerance and immunity in host protection against infection
Miguel P. Soares, Luis Teixeira & Luis F. Moita
p83 | doi:10.1038/nri.2016.136
Disease tolerance is a defence strategy that functions by improving tissue repair or by reducing the detrimental effect of inflammatory signals to prevent the harmful effects of pathogens. This Review describes the mechanisms underlying disease tolerance to infections and how these can be targeted therapeutically.