Nature – Volume 542 Number 7639 pp5-132 2 February 2017

Nature
Volume 542 Number 7639 pp5-132 2 February 2017
http://www.nature.com/nature/current_issue.html

Editorials
The time is ripe to reform the World Health Organization
As the public-health agency chooses a new leader, the media and politicians must be more realistic about what it can do.

Comment
Consider drug efficacy before first-in-human trials
Ethical review boards must focus on clinical promise as well as safety to hold the first tests of drugs in humans to a higher standard, say Jonathan Kimmelman and Carole Federico.