IVI [to 4 March 2017]

IVI [to 4 March 2017]
February 27, 2017
High incidences of typhoid and invasive Salmonella infection confirmed in sub-Saharan Africa
Findings of IVI-led study in 10 African countries published in The Lancet Global Health – High disease burden findings support the introduction of typhoid conjugate vaccines in high-incidence settings
An IVI-led study found that typhoid fever and invasive non-typhoidal Salmonella (iNTS) disease are major causes of invasive bacterial febrile illness in some African countries, and they most commonly afflict children in low and high population density settings.
Large variations exist in the disease burden of Salmonella Typhi and non-typhoidal Salmonella in sub-Saharan Africa, with rates of disease reaching as high as 383 per 100,000 persons per years (PY) for S. Typhi and 237 per 100,000 PY for iNTS disease in Burkina Faso. A rate of more than 100 per 100,000 is considered “high” as defined by the World Health Organization (WHO). Typhoid was found in both infants and school-age children, with a higher incidence in children below 15 years old, according to the study recently published in The Lancet Global Health