PNAS – Proceedings of the National Academy of Sciences of the United States of America

PNAS – Proceedings of the National Academy of Sciences of the United States
of America
http://www.pnas.org/content/early/
[Accessed 15 April 2017]
Editorial – Biological Sciences – Medical Sciences:
Simply put: Vaccination saves lives
Walter A. Orenstein and
Rafi Ahmed
PNAS 2017 ; published ahead of print April 10, 2017, doi:10.1073/pnas.1704507114
[See full text in Featured Journal Content at top]

Perspective: Emerging infectious diseases: A proactive approach
David E. Bloom, Steven Black, and Rino Rappuoli
PNAS 2017 ; published ahead of print April 10, 2017, doi:10.1073/pnas.1701410114
Abstract
Infectious diseases are now emerging or reemerging almost every year. This trend will continue because a number of factors, including the increased global population, aging, travel, urbanization, and climate change, favor the emergence, evolution, and spread of new pathogens. The approach used so far for emerging infectious diseases (EIDs) does not work from the technical point of view, and it is not sustainable. However, the advent of platform technologies offers vaccine manufacturers an opportunity to develop new vaccines faster and to reduce the investment to build manufacturing facilities, in addition to allowing for the possible streamlining of regulatory processes. The new technologies also make possible the rapid development of human monoclonal antibodies that could become a potent immediate response to an emergency. So far, several proposals to approach EIDs have been made independently by scientists, the private sector, national governments, and international organizations such as the World Health Organization (WHO). While each of them has merit, there is a need for a global governance that is capable of taking a strong leadership role and making it attractive to all partners to come to the same table and to coordinate the global approach.