New England Journal of Medicine
July 12, 2018 Vol. 379 No. 2
A Parallel Universe of Clinical Trials
Bernard Lo, M.D.
A recent clinical trial of a herpes simplex virus vaccine allegedly violated fundamental scientific, regulatory, and ethical safeguards. This case opens a window into a parallel universe that spurns the current system of clinical trial oversight in the United States and supports broad right-to-try laws allowing patients access to experimental therapies…