Milestones :: Perspectives :: Research
DRC – Ebola
37: Situation report on the Ebola outbreak in North Kivu
16 April 2019
…Implementation of ring vaccination protocol
:: As of 16 April 2019, 101,195 contacts and contacts of contacts have been vaccinated. Of those 26,613 were contacts and 74,367 contacts of contacts. The vaccinated people at risk included 29,688 HCWs/FLWs, and 26,361 children 1-6 years old. Detailed micro-plans are also in use to monitor the progress and number of cases with and without rings. Table 2 provides an overview of the status as of 15 April 2019.
:: Between 2-4 April 2019, Strategic Advisory Group of Experts (SAGE) convened a meeting to review epidemiological data from North Kivu for children below 1 year of age and for lactating women. Although clinical data on the safety and efficacy of the rVSV-ZEBOV-GP Ebola vaccine for these two specific groups are absent, SAGE considers that the high attack rates and high case fatality ratios for these groups, together with the accumulating data on vaccine safety and efficacy for other groups, justify inclusion of children who are above the age of 6 months and of lactating women in the ongoing ring vaccination efforts in North Kivu. SAGE strongly urged the implementation of studies to evaluate additional Ebola candidate vaccines, including where possible in pregnant and lactating women and in infants. (Please see here for a summary of the SAGE meeting highlights)
:: On 12 April 2019, INRB and WHO published a preliminary analysis of the efficacy of RVSV-ZEBOV-GP emerging from the DRC outbreak data (Please see here for preliminary analysis). The data suggest high efficacy of this candidate vaccine and of the ring vaccination in this outbreak.
:: There are currently 23 vaccination teams comprised of 276 Congolese vaccinators with basic GCP training, 50 Congolese with formal GCP training, and 43 experienced Guinean/African GCP researchers.
:: There is continuation of ring vaccination in Beni, Katwa, Butembo, Mandima, Bunia, Vuhovi, and Lubero health zones around confirmed cases, as well as front-line providers in Goma.
:: Current vaccination strategies being employed on the ground include site by site vaccination, simultaneous vaccination of contacts and their contacts in the community, healthcare worker vaccination, and targeted geographic vaccination of areas where contacts of contacts cannot be clearly identified due to insecurity…
Disease Outbreak News (DONs) –
Ebola virus disease – Democratic Republic of the Congo
11 April 2019
The rise in number of Ebola virus disease (EVD) cases observed in the North Kivu provinces of the Democratic Republic of the Congo continues this week. During the last 21 days (20 March to 9 April 2019), 57 health areas within 11 health zones reported new cases…
…WHO and partners in Risk Communication and Community Engagement are continuing with activities to build and maintain a trusting relationship between communities and the Ebola response teams. Dialogues with community committees are ongoing in the hotspot areas of Butembo, Katwa, and Vuhovi, and form a key part of a larger increase ownership of the Ebola response by the communities. Information about community disquiet are systematically collected and monitored to ensure that any misunderstanding leading to reluctance, refusal, or resistance of the Ebola response is followed up with and resolved as quickly as possible. This has been made possible by feedback from the community members, received through ongoing dialogue and various research activities within both the Democratic Republic of the Congo, and neighbouring areas.
In an effort to address the feedback received and specific concerns over the outbreak response, guided visits of the Ebola Treatment Centres (ETCs) in various affected areas have been organized. Students and community associations who attended these guided visits to the ETCs can see first-hand how EVD patients are treated and help stop the potential dissemination of misinformation surrounding EVD and the ongoing response efforts…