Value in Health
June 2019 Volume 22, Issue 6, p619-750
SYSTEMATIC LITERATURE REVIEW
Real-World Evidence in Healthcare Decision Making: Global Trends and Case Studies From Latin America
Nahila Justo, Manuel A. Espinoza, Barbara Ratto, Martha Nicholson, Diego Rosselli, Olga Ovcinnikova, Sebastián García Martí, Marcos B. Ferraz, Martín Langsam, Michael F. Drummond
Published in issue: June 2019
:: On collecting case studies from 4 South American countries, this study found that the collection and uses of real-world evidence (RWE) in healthcare decision making are inconsistent across regions, providers, and insurance schemes. RWE initiatives are somewhat hampered by fragmentation, lack of stewardship, and limited resources.
:: A literature review and database mapping revealed that in South America RWE is mainly used for pharmacovigilance and academic research, less so for HTA decision making or pricing negotiations, and not at all to inform early access schemes.