January 28, 2020, Vol 323, No. 4, Pages 295-386
DNA-Based Population ScreeningPotential Suitability and Important Knowledge Gaps
Michael F. Murray, MD; James P. Evans, MD, PhD; Muin J. Khoury, MD, PhD
JAMA. 2020;323(4):307-308. doi:10.1001/jama.2019.18640
This Viewpoint describes principles of DNA-based population screening and knowledge gaps that must be addressed before increased use of DNA screening to identify persons with monogenic risk can be implemented in population screening programs.