Heritable human genome editing: Research progress, ethical considerations, and hurdles to clinical practice

Cell
Mar 18, 2021 Volume 184 Issue 6 p1395-1650
https://www.cell.com/cell/issue?pii=S0092-8674(20)X0007-9

 

Heritable human genome editing: Research progress, ethical considerations, and hurdles to clinical practice
Jenna Turocy, Eli Y. Adashi, Dieter Egli
Our genomes at conception contribute substantially to our overall health, and heritable genome editing could provide many benefits by preventing disease from the beginning of life. Egli and colleagues review the scientific contributions to the field, the ethical challenges that cannot be overlooked, and the hurdles to be overcome prior to clinical practice.

Novel approaches for vaccine development

Cell
Mar 18, 2021 Volume 184 Issue 6 p1395-1650
https://www.cell.com/cell/issue?pii=S0092-8674(20)X0007-9

 

Novel approaches for vaccine development
Makda S. Gebre, Luis A. Brito, Lisa H. Tostanoski, Darin K. Edwards, Andrea Carfi, Dan H. Barouch
Vaccines play a critical role in global health, and Gebre et al. review the current state of three vaccine development platforms (mRNA vaccines, vector-based vaccines, and materials science approaches to vaccination).

Decoding Covid-19 with the SARS-CoV-2 Genome

Current Genetic Medicine Reports
Volume 9, issue 1, March 2021
https://link.springer.com/journal/40142/volumes-and-issues/9-1

 

Bioinformatics (A Pittman, Section Editor)
Decoding Covid-19 with the SARS-CoV-2 Genome
Authors (first, second and last of 5)
Phoebe Ellis, Ferenc Somogyvári, Gary R. McLean
Published: 09 January 2021
Pages: 1 – 12
SARS-CoV-2, the recently emerged coronavirus (CoV) that is responsible for the current global pandemic Covid-19, first appeared in late 2019 in Wuhan, China. Here, we summarise details of the SARS-CoV-2 genome to assist understanding of the emergence, evolution and diagnosis of this deadly new virus.

The Ethics of Repurposing Previously Collected Research Biospecimens in an Infectious Disease Pandemic

Ethics & Human Research
Volume 43, Issue 2 Pages: 1-48 March–April 2021
https://onlinelibrary.wiley.com/toc/25782363/current

 

Research ethics and pandemics • IRBs and AI research
Articles
Free Access
The Ethics of Repurposing Previously Collected Research Biospecimens in an Infectious Disease Pandemic
Benjamin E. Berkman et al
Pages: 2-18
First Published: 23 February 2021

Governing AI‐Driven Health Research: Are IRBs Up to the Task?

Ethics & Human Research
Volume 43, Issue 2 Pages: 1-48 March–April 2021
https://onlinelibrary.wiley.com/toc/25782363/current

 

Articles
Governing AI‐Driven Health Research: Are IRBs Up to the Task?
Phoebe Friesen, et al.
Pages: 35-42
First Published: 08 March 2021
ABSTRACT
Many are calling for concrete mechanisms of oversight for health research involving artificial intelligence (AI). In response, institutional review boards (IRBs) are being turned to as a familiar model of governance. Here, we examine the IRB model as a form of ethics oversight for health research that uses AI. We consider the model’s origins, analyze the challenges IRBs are facing in the contexts of both industry and academia, and offer concrete recommendations for how these committees might be adapted in order to provide an effective mechanism of oversight for health‐related AI research.

Supporting communities of practice – A Journey to effective problem-solving

Gates Open Research
https://gatesopenresearch.org/browse/articles
[Accessed 20 Mar 2021]

 

Open Letter metrics
Revised
Supporting communities of practice – A Journey to effective problem-solving [version 2; peer review: 2 approved with reservations, 1 not approved]
Christina Hanschke, James Baer, Alok Gangaramany, Janneke Verheijen, Nduku Kilonzo, Bryan Okiya, Leonard Kibe Ranji, Stephen Amolo Amolo, Simon Zwane, Rejoice Nkambule, Violet Buluma, Sylvia Ojoo, Susan Kim, Sharon Kibwana, Mark Dybul, Steve Kretschmer
Peer Reviewers Carlos Toledo; Julia Samuelson; Tracy Johnson
Funder: Bill and Melinda Gates Foundation
LATEST VERSION PUBLISHED 16 Mar 2021
Abstract
In contexts of scarce resources, varied assets, and diverse communities, engaging local stakeholders in the problem-solving process is critical to develop interventions for HIV prevention and treatment. Communities of practice (CoPs) – groups of people organized around a key purpose and a delivery point – can develop expertise in identifying their local community’s key challenges and selecting viable solutions. We propose a framework, adapted from the CoP model developed by Etienne Wenger, for systematically understanding the stages a CoP may go through as it develops its capacity to identify and solve problems and implement good practices.

Countries with delayed COVID-19 introduction – characteristics, drivers, gaps, and opportunities

Globalization and Health
http://www.globalizationandhealth.com/
[Accessed 20 Mar 2021]

 

Countries with delayed COVID-19 introduction – characteristics, drivers, gaps, and opportunities
Authors: Zheng Li, Cynthia Jones, Girum S. Ejigu, Nisha George, Amanda L. Geller, Gregory C. Chang, Alys Adamski, Ledor S. Igboh, Rebecca D. Merrill, Philip Ricks, Sara A. Mirza and Michael Lynch
Content type: Research
17 March 2021
…This analysis aimed to 1) assess characteristics, capability to detect and monitor COVID-19, and disease control measures in these 24 countries, 2) understand potential factors for the reported delayed COVID-19 introduction, and 3) identify gaps and opportunities for outbreak preparedness, particularly in low and middle-income countries (LMICs). We collected and analyzed publicly available information on country characteristics, COVID-19 testing, influenza surveillance, border measures, and preparedness activities in these countries. We also assessed the association between the temporal spread of COVID-19 in all countries with reported cases with globalization indicator and geographic location.

Disability inclusion in humanitarian action

Humanitarian Exchange Magazine
Number 78, October 2020
https://odihpn.org/magazine/inclusion-of-persons-with-disabilities-in-humanitarian-action-what-now/

 

Disability inclusion in humanitarian action
by HPN October 2020
The theme of this edition of Humanitarian Exchange, co-edited with Sherin Alsheikh Ahmed from Islamic Relief Worldwide, is disability inclusion in humanitarian action. Persons with disabilities are not only disproportionately impacted by conflicts, disasters and other emergencies, but also face barriers to accessing humanitarian assistance. At the same time, global commitments and standards and the IASC Guidelines on the inclusion of persons with disabilities in humanitarian action all emphasise how persons with disabilities are also active agents of change. Disability and age-focused organisations have led on testing and demonstrating how inclusion can be done better. Yet despite this progress, challenges to effective inclusion remain.

As Kirstin Lange notes in the lead article, chief among these challenges is humanitarian agencies’ lack of engagement with organisations of persons with disabilities. Simione Bula, Elizabeth Morgan and Teresa Thomson look at disability inclusion in humanitarian response in the Pacific, and Kathy Al Jubeh and Alradi Abdalla argue for a ‘participation revolution’, building on learning from the gender movement. Tchaurea Fleury and Sulayman AbdulMumuni Ujah outline how the Bridge Article 11 training initiative is encouraging constructive exchange between humanitarian and disability actors. The lack of good, disaggregated data is highlighted by Sarah Collinson; Frances Hill, Jim Cranshaw and Carys Hughes emphasise the need for training resources in local languages and accessible formats; and Sophie Van Eetvelt and colleagues report on a review of the evidence on inclusion of people with disabilities and older people.

Rebecca Molyneux and co-authors analyse the findings of a review of a DFID programme in north-east Nigeria, while Carolin Funke highlights the importance of strategic partnerships between disability-focused organisations, drawing on her research in Cox’s Bazar. Sherin Alsheikh Ahmed describes Islamic Relief Worldwide’s approach to mainstreaming protection and inclusion, while Pauline Thivillier and Valentina Shafina outline IRC’s Client Responsive Programming. The edition ends with reflections by Mirela Turcanu and Yves Ngunzi Kahashi on CAFOD’s SADI approach.

Leveraging on the genomics and immunopathology of SARS-CoV-2 for vaccines development: prospects and challenges

Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 3, 2021
https://www.tandfonline.com/toc/khvi20/current

 

Review
Leveraging on the genomics and immunopathology of SARS-CoV-2 for vaccines development: prospects and challenges
Idris Nasir Abdullahi, et al
Pages: 620-637
Published online: 16 Sep 2020

COVID-19 outbreak: a potential threat to routine vaccination programme activities in Nigeria

Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 3, 2021
https://www.tandfonline.com/toc/khvi20/current

 

article commentary
COVID-19 outbreak: a potential threat to routine vaccination programme activities in Nigeria
Olorunfemi Akinbode Ogundele, Ayodeji Andrew Omotoso & Aderonke Tolulope Fagbemi
Pages: 661-663
Published online: 29 Sep 2020

Modelling of optimal vaccination strategies in response to a bioterrorism associated smallpox outbreak

Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 3, 2021
https://www.tandfonline.com/toc/khvi20/current

 

Article
Modelling of optimal vaccination strategies in response to a bioterrorism associated smallpox outbreak
Valentina Costantino, Mohana Kunasekaran & Chandini Raina MacIntyre
Pages: 738-746
Published online: 02 Dec 2020

Hypothetical assessment of efficiency, willingness-to-accept and willingness-to-pay for dengue vaccine and treatment: a contingent valuation survey in Bangladesh

Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 3, 2021
https://www.tandfonline.com/toc/khvi20/current

 

Article
Hypothetical assessment of efficiency, willingness-to-accept and willingness-to-pay for dengue vaccine and treatment: a contingent valuation survey in Bangladesh
K M Ariful Kabir, Aya Hagishima & Jun Tanimoto
Pages: 773-784
Published online: 21 Aug 2020

Knowledge, attitude, perception of Muslim parents towards vaccination in Malaysia

Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 3, 2021
https://www.tandfonline.com/toc/khvi20/current

 

Article
Knowledge, attitude, perception of Muslim parents towards vaccination in Malaysia
Mohammed Tahir Ansari, Nurul Nadia Jamaluddin, Thiya Anissa Ramlan, Nurshahiera Zamri, Shahnaz Majeed, Vishal Badgujar, Farheen Sami, M Saquib Hasnain & Helvinder Kaur Balbir Singh
Pages: 785-790
Published online: 24 Aug 2020

Human papillomavirus vaccination: coverage rate, knowledge, acceptance, and associated factors in college students in mainland China

Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 3, 2021
https://www.tandfonline.com/toc/khvi20/current

 

Article
Human papillomavirus vaccination: coverage rate, knowledge, acceptance, and associated factors in college students in mainland China
Che Deng, Xiaoli Chen & Yanqun Liu
Pages: 828-835
Published online: 01 Sep 2020

COVID-19 Vaccination in Pregnant and Lactating Women

JAMA
March 16, 2021, Vol 325, No. 11, Pages 1025-1118
https://jamanetwork.com/journals/jama/currentissue

 

Viewpoint
COVID-19 Vaccination in Pregnant and Lactating Women
Emily H. Adhikari, MD; Catherine Y. Spong, MD
free access has active quiz has multimedia has audio
JAMA. 2021;325(11):1039-1040. doi:10.1001/jama.2021.1658
This Viewpoint discusses the need for shared decision-making when counseling pregnant and nursing women about the unstudied benefits and risks COVID-19 vaccination, calling for rigorously designed studies with real-time, proactive data collection to establish evidence as quickly as possible about coronavirus vaccine safety in mothers and their infants.

Conversations with Dr Bauchner: Coronavirus Vaccination in Pregnant and Breastfeeding Individuals

Protecting Pregnant Women and Their Infants From COVID-19: Clues From Maternal Viral Loads, Antibody Responses, and Placentas

JAMA
March 16, 2021, Vol 325, No. 11, Pages 1025-1118
https://jamanetwork.com/journals/jama/currentissue

 

Invited Commentary
Protecting Pregnant Women and Their Infants From COVID-19: Clues From Maternal Viral Loads, Antibody Responses, and Placentas
Denise J. Jamieson, MD, MPH; Sonja A. Rasmussen, MD, MS

Involving Pregnant Individuals in Clinical Research on COVID-19 Vaccines

JAMA
March 16, 2021, Vol 325, No. 11, Pages 1025-1118
https://jamanetwork.com/journals/jama/currentissue

 

Involving Pregnant Individuals in Clinical Research on COVID-19 Vaccines
Diana W. Bianchi, MD; Lisa Kaeser, JD; Alison N. Cernich, PhD
free access has multimedia has audio
JAMA. 2021;325(11):1041-1042. doi:10.1001/jama.2021.1865
This Viewpoint from the National Institute of Child Health and Human Development emphasizes the need to use existing data sources and develop partnerships, infrastructure, and ethical and regulatory standards to generate data about the safety and efficacy of COVID-19 vaccination in pregnant individuals.

Pregnancy, Postpartum Care, and COVID-19 Vaccination in 2021

JAMA
March 16, 2021, Vol 325, No. 11, Pages 1025-1118
https://jamanetwork.com/journals/jama/currentissue

 

Women’s Health
Pregnancy, Postpartum Care, and COVID-19 Vaccination in 2021
Sonja A. Rasmussen, MD, MS; Denise J. Jamieson, MD, MPH
free access has active quiz has multimedia has audio
JAMA. 2021;325(11):1099-1100. doi:10.1001/jama.2021.1683
This JAMA Insights review summarizes the epidemiology of SARS-CoV-2 infection in pregnant and lactating women, its effects on perinatal outcomes, and compiles guidance from the CDC, FDA, and obstetrics-gynecology specialty organizations on the safety of coronavirus vaccines during pregnancy and while breastfeeding.

Reports of Anaphylaxis After Receipt of mRNA COVID-19 Vaccines in the US—December 14, 2020-January 18, 2021

JAMA
March 16, 2021, Vol 325, No. 11, Pages 1025-1118
https://jamanetwork.com/journals/jama/currentissue

 

Reports of Anaphylaxis After Receipt of mRNA COVID-19 Vaccines in the US—December 14, 2020-January 18, 2021
Tom T. Shimabukuro, MD, MPH, MBA; Matthew Cole, MPH; John R. Su, MD, PhD, MPH
free access has active quiz has multimedia has audio
JAMA. 2021;325(11):1101-1102. doi:10.1001/jama.2021.1967
This JAMA Insights review provides clinical details of anaphylactic reactions reported to and verified by the CDC in the first month of use of the Pfizer-BioNTech and Moderna COVID-19 vaccines in the US, December 14, 2020-January 18, 2021.

The Search for an HIV Cure: Where Do We Go From Here?

Journal of Infectious Diseases
Volume 223, Issue Supplement_1, 1 February 2021
https://academic.oup.com/jid/issue/223/Supplement_1

 

SUPPLEMENT – Challenges and Promising Approaches for HIV Remission
Articles
The Search for an HIV Cure: Where Do We Go From Here?
Jonathan Z Li, Rajesh T Gandhi
The Journal of Infectious Diseases, Volume 223, Issue Supplement_1, 1 February 2021, Pages S1–S3, https://doi.org/10.1093/infdis/jiaa738

Scientific interactions in a virtual world

Nature Human Behaviour
Volume 5 Issue 3, March 2021
https://www.nature.com/nathumbehav/volumes/5/issues/3

 

Editorial | 19 March 2021
Scientific interactions in a virtual world
COVID-19 has forced a rethink of many practices we previously took for granted, and academic travel is no exception. Virtual conferences have demonstrated their promise for encouraging a more equitable and environmentally friendly future.

Changing scientific meetings for the better

Nature Human Behaviour
Volume 5 Issue 3, March 2021
https://www.nature.com/nathumbehav/volumes/5/issues/3

 

Comment | 15 March 2021
Changing scientific meetings for the better
Conferences are a pivotal part of the scientific enterprise, but large in-person meetings have several disadvantages. As the pandemic experience has shown, online meetings are a viable alternative. Accelerating efforts to improve conferences in virtual formats can lead to a more equitable and sustainable conference culture.
Sarvenaz Sarabipour, Aziz Khan  & Tomislav Mestrovic

Promoting diagnostics as a global good

Nature Medicine
Volume 27 Issue 3, March 2021
https://www.nature.com/nm/volumes/27/issues/3

 

Comment | 15 March 2021
Promoting diagnostics as a global good
The COVID-19 pandemic has reasserted the central role of effective diagnostics in the response to outbreaks. But a lack of coordination still hampers widespread access to these critical tools. A diagnostics agenda for global health is urgently needed for the promotion of diagnostics as a global good and to ensure their delivery.
Catharina Boehme, Emma Hannay  & Madhukar Pai

Beyond recruitment: good participatory practice enhances the impact of research in a pandemic

Nature Medicine
Volume 27 Issue 3, March 2021
https://www.nature.com/nm/volumes/27/issues/3

 

Comment | 15 March 2021
Beyond recruitment: good participatory practice enhances the impact of research in a pandemic
In a health emergency, clear, two-way communication between researchers and a broad spectrum of stakeholders is essential to establishing trust—a prerequisite for meaningful uptake of new treatments and vaccines.
Barthalomew Wilson, Katharine Wright & Elizabeth Higgs

Developing therapeutic approaches for twenty-first-century emerging infectious viral diseases

Nature Medicine
Volume 27 Issue 3, March 2021
https://www.nature.com/nm/volumes/27/issues/3

 

Review Article | 15 March 2021
Developing therapeutic approaches for twenty-first-century emerging infectious viral diseases
As the emergence of viral diseases is expected to accelerate, proactive programs to develop broadly active family-specific and cross-family antiviral therapeutics will be key to prepare for future disease outbreaks.
Rita M. Meganck & Ralph S. Baric

A systematic review on improving implementation of the revitalised integrated disease surveillance and response system in the African region: A health workers’ perspective

PLoS One
http://www.plosone.org/
[Accessed 20 Mar 2021]

 

A systematic review on improving implementation of the revitalised integrated disease surveillance and response system in the African region: A health workers’ perspective
Arthur K. S. Ng’etich, Kuku Voyi, Ruth C. Kirinyet, Clifford M. Mutero
Research Article | published 19 Mar 2021 PLOS ONE
https://doi.org/10.1371/journal.pone.0248998

Vaccinating the oldest against COVID-19 saves both the most lives and most years of life

PNAS – Proceedings of the National Academy of Sciences of the United States of America
March 16, 2021; vol. 118 no. 11
https://www.pnas.org/content/118/11

 

Brief Report Open Access
Vaccinating the oldest against COVID-19 saves both the most lives and most years of life
Joshua R. Goldstein, Thomas Cassidy, and Kenneth W. Wachter
PNAS March 16, 2021 118 (11) e2026322118; https://doi.org/10.1073/pnas.20263221

The right to health, public health and COVID-19: a discourse on the importance of the enforcement of humanitarian and human rights law in conflict settings for the future management of zoonotic pandemic diseases

Public Health
Volume 192 Pages 1-74 (March 2021)
https://www.sciencedirect.com/journal/public-health/vol/192/suppl/C

 

Review article Full text access
The right to health, public health and COVID-19: a discourse on the importance of the enforcement of humanitarian and human rights law in conflict settings for the future management of zoonotic pandemic diseases
M.C. Van Hout, J.S.G. Wells
Pages 3-7
Abstract
Objectives
The catastrophic effects of armed conflict, particularly prolonged armed conflict, on individual and public health are well established. The ‘right’ to healthcare during armed conflict and its lack of enforcement despite a range of United Nations mandated requirements regarding health and healthcare provisions is likely to be a significant feature in future conflicts, as zoonotic-induced pandemics become a more common global public health challenge. The issue of enforcement of health rights assurance and its implications for the public health management of global pandemics such as coronavirus disease 2019 (COVID-19) in and between countries and regions in conflict is the objective of this Review.

Justice, diversity, and research ethics review

Science
19 March 2021 Vol 371, Issue 6535
http://www.sciencemag.org/current.dtl

 

Policy Forum
Justice, diversity, and research ethics review
By David H. Strauss, Sarah A. White, Barbara E. Bierer
Science19 Mar 2021 : 1209-1211 Full Access
It is time for institutional review boards and research ethics committees to address the ethics of inclusion
Summary
The disproportionate impact of COVID-19 on certain populations, such as Black, Latinx, and Indigenous populations in the United States, has focused attention on inequalities in health and on the need to increase enrollment of racial and ethnic minorities and other underrepresented groups in biomedical research (1). Yet too often, in the United States and globally, participant enrollment in research has not reflected the demographic composition of the general population, those affected by the health conditions being studied, or those for whom the investigational product is intended (2), with racial and ethnic minorities and the young and the elderly, among others, being consistently underrepresented (3). Underlying causes for this underrepresentation have been described (4, 5), but change has been slow. Notwithstanding the roles of other stakeholders in addressing this issue, we maintain that the specific value of institutional review boards (IRBs) and research ethics committees (RECs) in promoting diversity has been underrecognized and their authority underutilized. Here, we substantiate the role of and outline practical steps for the IRB and REC (hereafter “IRB”) to help achieve greater diversity in clinical research.

Sex difference in the immunogenicity of the quadrivalent Human Papilloma Virus vaccine: Systematic review and meta-analysis

Vaccine
Volume 39, Issue 12 Pages 1667-1796 (19 March 2021)
https://www.sciencedirect.com/journal/vaccine/vol/39/issue/12

 

Review article Open access
Sex difference in the immunogenicity of the quadrivalent Human Papilloma Virus vaccine: Systematic review and meta-analysis
Lafi Aldakak, Vera Maria Huber, Frank Rühli, Nicole Bender
Pages 1680-1686

Perspectives on the receipt of a COVID-19 vaccine: A survey of employees in two large hospitals in Philadelphia

Vaccine
Volume 39, Issue 12 Pages 1667-1796 (19 March 2021)
https://www.sciencedirect.com/journal/vaccine/vol/39/issue/12

 

Research article Full text access
Perspectives on the receipt of a COVID-19 vaccine: A survey of employees in two large hospitals in Philadelphia
Barbara J. Kuter, Safa Browne, Florence M. Momplaisir, Kristen A. Feemster, … Paul A. Offit
Pages 1693-1700
Health care personnel have been identified by the ACIP as a priority group for COVID-19 vaccination. We conducted a survey in November-December 2020 at two large, academic hospitals in Philadelphia to evaluate the intention of hospital employees to be vaccinated.

Estimating pneumococcal vaccine coverage among Australian Indigenous children and children with medically at-risk conditions using record linkage

Vaccine
Volume 39, Issue 12 Pages 1667-1796 (19 March 2021)
https://www.sciencedirect.com/journal/vaccine/vol/39/issue/12

 

Research article Abstract only
Estimating pneumococcal vaccine coverage among Australian Indigenous children and children with medically at-risk conditions using record linkage
Alamgir Kabir, Anthony T. Newall, Deborah Randall, Rob Menzies, … Heather F. Gidding
Pages 1727-1735

Improving adolescent human papillomavirus (HPV) immunization uptake in school-based health centers through awareness campaigns

Vaccine
Volume 39, Issue 12 Pages 1667-1796 (19 March 2021)
https://www.sciencedirect.com/journal/vaccine/vol/39/issue/12

 

Research article Abstract only
Improving adolescent human papillomavirus (HPV) immunization uptake in school-based health centers through awareness campaigns
Madhura S. Rane, Libby C. Page, Emma McVeigh, Kaetlin Miller, … Jeffrey S. Duchin
Pages 1765-1772

The Impact of a Single Educational Lecture on the Vaccine Confidence among Pregnant Women and Young Mothers

Vaccines — Open Access Journal
http://www.mdpi.com/journal/vaccines
(Accessed 20 Mar 2021)

 

Open Access Article
The Impact of a Single Educational Lecture on the Vaccine Confidence among Pregnant Women and Young Mothers
by Katarzyna Tkaczyszyn et al
Vaccines 2021, 9(3), 290; https://doi.org/10.3390/vaccines9030290 (registering DOI) – 20 Mar 2021
Abstract
Background: We investigated the impact of a single unstructured educational lecture about vaccinations on the vaccine confidence in volunteer participants. Methods: We conducted a survey-based study during a series of open meetings related to pregnancy and parenting. Before and after the pediatrician’s lecture […]

Perception of COVID-19 Vaccination Amongst Physicians in Colombia

Vaccines — Open Access Journal
http://www.mdpi.com/journal/vaccines
(Accessed 20 Mar 2021)

 

Open Access Article
Perception of COVID-19 Vaccination Amongst Physicians in Colombia
by Jorge L. Alvarado-Socarras et al
Vaccines 2021, 9(3), 287; https://doi.org/10.3390/vaccines9030287 (registering DOI) – 19 Mar 2021
Abstract
Introduction: The SARS-CoV-2/COVID-19 pandemic has triggered the need to develop rapidly effective and safe vaccines to prevent infection, particularly in those at-risk populations such as medical personnel. This study’s objective was to assess the perception of COVID-19 vaccination amongst Colombian physicians featuring […]

Vaccination Coverage for Routine Vaccines and Herd Immunity Levels against Measles and Pertussis in the World in 2019

Vaccines — Open Access Journal
http://www.mdpi.com/journal/vaccines
(Accessed 20 Mar 2021)

 

Open Access Article
Vaccination Coverage for Routine Vaccines and Herd Immunity Levels against Measles and Pertussis in the World in 2019
by Pedro Plans-Rubió
Vaccines 2021, 9(3), 256; https://doi.org/10.3390/vaccines9030256 – 13 Mar 2021
Abstract
In 2012, the World Health Organization (WHO) established the Global Vaccine Action Plan with the objective to promote essential vaccinations in all countries and achieve at least 90% vaccination coverage for all routine vaccines by 2020. The study assessed the mean percentages of […

Media/Policy Watch

Media/Policy Watch
This watch section is intended to alert readers to substantive news, analysis and opinion from the general media and selected think tanks and similar organizations on vaccines, immunization, global public health and related themes. Media Watch is not intended to be exhaustive, but indicative of themes and issues CVEP is actively tracking. This section will grow from an initial base of newspapers, magazines and blog sources, and is segregated from Journal Watch above which scans the peer-reviewed journal ecology.
We acknowledge the Western/Northern bias in this initial selection of titles and invite suggestions for expanded coverage. We are conservative in our outlook in adding news sources which largely report on primary content we are already covering above. Many electronic media sources have tiered, fee-based subscription models for access. We will provide full-text where content is published without restriction, but most publications require registration and some subscription level.

 

The Atlantic
http://www.theatlantic.com/magazine/
Accessed 20 Mar 2021
Accessed 20 Mar 2021
[No new, unique, relevant content]

 

BBC
http://www.bbc.co.uk/
Accessed 20 Mar 2021
Covid: Rich states ‘block’ vaccine plans for developing nations
March 19, 2021
Wealthy countries – including the UK – are blocking proposals to help developing nations increase their vaccine manufacturing capabilities, documents leaked to BBC Newsnight show.
Several poorer countries have asked the World Health Organization to help them.
But richer nations are pushing back on provisions in international law that would enable them to achieve this.
This is according to a leaked copy of the negotiating text of a WHO resolution on the issue.
Among those richer nations are the UK, the US, as well as the European Union…

 

The Economist
http://www.economist.com/
Accessed 20 Mar 2021
[No new, unique, relevant content]

 

Financial Times
https://www.ft.com/
Accessed 20 Mar 2021
Olympic Games
Japan bans foreign spectators from Tokyo Olympics
March 20, 2021

The Big Read
‘Everyone’s scrambling and hoarding’: Europe’s vaccine blunders
The faltering immunisation campaign has created a picture of rattled leaders losing their nerve as the pandemic worsens
March 19, 2021
…The EU’s faltering vaccination campaign has been hamstrung by a botched central procurement process, supply shortfalls, logistical hurdles and excessive risk aversion from some national medical regulators. The suspension of the jab, albeit only for three days in most EU nations, was another hammer blow, with experts warning it would undermine public confidence and feed conspiracy theories about vaccine risks…

Coronavirus Business Update
AstraZeneca jabs resume but vaccination tensions deepen
March 19, 2021

Covid-19 vaccines
Scandinavian countries keep AstraZeneca vaccine on hold
France recommends use only for those aged 55 and over as other European nations resume rollout
Norway, Denmark and Sweden have continued to pause the use of the Oxford/AstraZeneca Covid-19 vaccine while France recommended not to use it on people under 55, as other European nations slowly resumed the rollout of the jab amid questions over its side effects.
The countries said they wanted to further analyse the vaccine’s possible role in a number of unusual deaths involving blood clots, despite an assessment from the European Medicines Agency on Thursday that the AstraZeneca vaccine was “effective and safe”.
The Norwegian Institute of Public Health said it would take a decision on whether to restart the vaccine next week as it needed a “fuller picture of the situation”…

Bottom of Form

 

Forbes
http://www.forbes.com/
Accessed 20 Mar 2021
Mar 19, 2021
U.S. Meets Major Vaccine Milestone On Friday, But Vaccine Hesitancy Is High
Over 115 million doses of Covid-19 vaccine have been administered in the U.S., including 100 million since January 20.
By Melissa Holzberg Forbes Staff

Mar 18, 2021
Can Employers Force Employees To Get Vaccinated Or Return To The Office?
Some 69% of Americans believe employees should decide for themselves whether to get vaccinated instead of employers imposing vaccine mandates.
By Kristin Stoller Forbes Staff

 

Foreign Affairs
http://www.foreignaffairs.com/
Accessed 20 Mar 2021
America Can—and Should—Vaccinate the World
The Case for an All-Out Global Approach to Ending the Pandemic
By Helene Gayle, Gordon LaForge, and Anne-Marie Slaughter
March 19, 2021
After a virtual “Quad summit” last Friday, the leaders of the United States, India, Japan, and Australia announced that they would cooperate to deliver one billion vaccine doses in the Indo-Pacific, directly countering China’s lead in distributing vaccines to the region. The agreement brings together Indian manufacturing and U.S., Japanese, and Australian financing, logistics, and technical assistance to help immunize hundreds of millions of people by the end of 2022. Headlines over the weekend proclaimed that the administration of U.S. President Joe Biden was preparing to catch up in global vaccine diplomacy. Yesterday the administration took a further step in this direction, leaking to reporters that it would lend four million AstraZeneca doses to Mexico and Canada.
These initiatives come not a moment too soon…

 

Foreign Policy
http://foreignpolicy.com/
Accessed 20 Mar 2021
[No new, unique, relevant content]

 

New Yorker
http://www.newyorker.com/
Accessed 20 Mar 2021
[No new, unique, relevant content]

 

New York Times
http://www.nytimes.com/
Accessed 20 Mar 2021
Asia Pacific
Spectators From Overseas Are Barred From Tokyo Olympics
The move, announced Saturday, is a significant concession to the realities of the pandemic, even as organizers remain determined to hold the Games this summer.
By Motoko Rich and Ben Dooley
PRINT EDITION March 21, 2021

Europe
Europe Begins Administering AstraZeneca Vaccines Again
On Friday, governments across Europe raced to restart use of AstraZeneca’s coronavirus vaccine after the announcement from the European Union’s top drug regulator on Thursday that the shots were safe and effective.
By The Associated Press March 19, 2021

Europe
Europe’s Vaccine Ethics Call: Do No Harm and Let More Die?
Ethicists are worried about the gamble Germany took to halt AstraZeneca doses over seven cases of blood clots. It will not be the last time hard decisions are made in this pandemic.
By Max Fisher
PRINT EDITION March 20, 2021, Page A6

Technology
Walmart becomes largest U.S. vaccine provider to join push for digital vaccination credentials.
The retail giant joined an international push to provide standardized digital vaccination credentials.
By Natasha Singer March 17

World
On vaccines, Trump tells his hesitant supporters, ‘I would recommend it.’
A third of Republicans said in a recent poll that they would not be vaccinated, compared with 10 percent of Democrats, and another 20 percent of Republicans said they were unsure.
By Bryan Pietsch and Annie Karni

 

Washington Post
https://www.washingtonpost.com/
Accessed 20 Mar 2021
Egypt receives 2nd shipment of vaccine as gift from China
The 300,000-dose shipment of the vaccine manufactured by China…
Mar 20, 2021

Mexico: 2.7M U.S. vaccine doses to arrive next week
Mar 19, 2021

Indonesia clears use of AstraZeneca vaccine to resume after European Union’s drug regulator said
Associated Press · Mar 19, 2021

Video
Laurie Garrett says vaccine hesitancy is biggest threat from AstraZeneca fallout
Journalist and author Laurie Garrett says one of the biggest threats from the suspension of the AstraZeneca vaccine in several European countries is increased vaccine hesitancy. “The biggest risk here — and it is huge — is this is in some of the very same countries… where there was a huge amount of vaccine hesitancy.”
Washington Post Live · Mar 17, 2021

How Chile’s vaccination push outpaced the rest of the Western Hemisphere
…have delayed vaccine rollouts in other countries. It has secured enough doses to vaccinate its entire adult…
Antonia Noori Farzan · Americas · Mar 17, 2021

Think Tanks et al

Think Tanks et al

Brookings
http://www.brookings.edu/
Accessed 20 Mar 2021
Brown Center Chalkboard
Coronavirus and schools: Reflections on education one year into the pandemic
Daphna Bassok, Lauren Bauer, Stephanie Riegg Cellini, Helen Shwe Hadani, Michael Hansen, Douglas N. Harris, Brad Olsen, Richard V. Reeves, Jon Valant, and Kenneth K. Wong
Friday, March 12, 2021
 
 
Center for Global Development [to 20 Mar 2021]
http://www.cgdev.org/page/press-center
Publication
[No new digest content identified]
 
 
Chatham House [to 20 Mar 2021]
https://www.chathamhouse.org/
Accessed 20 Mar 2021
Brussels Silent on Vaccinating Undocumented Migrants
Often working in frontline jobs, and therefore among those most exposed to and likely to transmit COVID-19, undocumented migrants are also the least protected.
Expert Comment
Anna Iasmi Vallianatou Stavros Niarchos Foundation Academy Fellow, Europe Programme
Emily Venturi Schwarzman Academy Fellow, Asia-Pacific Programme

Sophie Zinser Schwarzman Academy Fellow, Asia-Pacific Programme and Middle East North Africa Programme
16 March 2021
During the last few weeks, the European Union (EU) has been widely criticized for its ‘failed’ vaccination strategy. But with all the focus on the general slowness of the EU in vaccinating the populations of its member states, another aspect of the EU’s public health crisis has been ignored.
Undocumented persons are being left out of COVID-19 national vaccination programmes and Brussels remains alarmingly silent about it. This should come as no surprise as migration is a toxic issue and governments in EU countries are now under immense pressure to vaccinate their own citizens as soon as possible.
Undocumented migrants are the least protected, but similar challenges extend to individuals without residence or secure legal status, such as asylum seekers, homeless, and Roma people – making the true number of people being left behind much higher
But the race towards herd immunity cannot afford the luxury of another EU standstill. It is past time for member states and EU institutions to unequivocally include all who reside within EU territories in their pandemic responses, irrespective of legal status…

 
 
CSIS
https://www.csis.org/
Accessed 20 Mar 2021
Upcoming Event
Africa’s Global Reset: Foreign Relations in a Post-Pandemic Era
March 23, 2021

Podcast Episode
John Nkengasong of Africa CDC On Learning From the Pandemics of the Past
March 18, 2021 | By Katherine E. Bliss, J. Stephen Morrison

 
 

Kaiser Family Foundation
https://www.kff.org/search/?post_type=press-release
Accessed 20 Mar 2021
March 19, 2021 News Release
KFF/Post Survey of Frontline Health Care Workers Finds Nearly Half Remain Unvaccinated
As of early March, just over half (52%) of frontline health care workers say they have received at least one dose of a COVID-19 vaccine, leaving 48% who have not, a new KFF/The Washington Post national survey of health care workers finds. Most who work in hospitals (66%) and outpatient…

March 11, 2021 News Release
KFF COVID-19 Vaccine Monitor: The Impact of the COVID-19 Pandemic on LGBT People
The latest report from the KFF COVID-19 Vaccine Monitor examines how the COVID-19 pandemic has impacted the lives of lesbian, gay, bisexual and transgender (LGBT) people and finds that larger shares of LGBT adults report economic losses and mental health struggles than their non-LGBT counterparts. Based on data gathered on…
 
 
Urban Institute [to 20 Mar 2021]
https://www.urban.org/publications
Publications
[No new digest content identified]
 
 
World Economic Forum [to 20 Mar 2021]
https://agenda.weforum.org/news/
Media
Top electronics brands and global organizations launch first private sector alliance for circular electronics
News 18 Mar 2021
· The World Economic Forum convened a special dialogue with Egyptian Prime Minister Dr. Mostafa Madbouly and more than 80 business leaders from around the world
· The virtual session offered participants an insight into Egypt’s post-COVID-19 strategic priorities and structural reforms

Vaccines and Global Health: The Week in Review :: 13 March 2021

Vaccines and Global Health: The Week in Review is a weekly digest  summarizing news, events, announcements, peer-reviewed articles and research in the global vaccine ethics and policy space. Content is aggregated from key governmental, NGO, international organization and industry sources, key peer-reviewed journals, and other media channels. This summary proceeds from the broad base of themes and issues monitored by the Center for Vaccine Ethics & Policy in its work: it is not intended to be exhaustive in its coverage. You are viewing the blog version of our weekly digest, typically comprised of between 30 and 40 posts below all dated with the current issue date

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– pdf version A pdf of the current issue is available here: 

– blog edition: comprised of the approx. 35+ entries posted below.

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– Links:  We endeavor to test each link as we incorporate it into any post, but recognize that some links may become “stale” as publications and websites reorganize content over time. We apologize in advance for any links that may not be operative. We believe the contextual information in a given post should allow retrieval, but please contact us as above for assistance if necessary.

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David R. Curry, MS
Executive Director
Center for Vaccine Ethics and Policy