Sep 30, 2021 Volume 184 Issue 20 p5071-5260
COVID-19 vaccines: Keeping pace with SARS-CoV-2 variants
Muge Cevik, Nathan D. Grubaugh, Akiko Iwasaki, Peter Openshaw
As the SARS-CoV-2 epidemic evolves, new variants continue to emerge. Some highly transmissible variants, such as Delta, also raised concerns about the effectiveness provided by current vaccines. Understanding immunological correlates of protection and how laboratory findings correspond to clinical effectiveness is imperative to shape future vaccination strategies.