Pre-Print Servers

Gates Open Research
https://gatesopenresearch.org/browse/articles
[Accessed 4 Dec 2021]

No new digest content identified.

medRxiv
https://www.medrxiv.org/content/about-medrxiv
medRxiv is a free online archive and distribution server for complete but unpublished manuscripts (preprints) in the medical, clinical, and related health sciences. Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information. medRxiv is for the distribution of preprints – complete but unpublished manuscripts – that describe human health research conducted, analyzed, and interpreted according to scientific principles…
[Accessed 4 Dec 2021]
Selected Content
Safety, tolerability, and immunogenicity of a SARS-CoV-2 recombinant spike protein vaccine: a randomised, double-blind, placebo-controlled, phase 1-2 clinical trial (ABDALA Study).
Francisco Hernandez-Bernal, Maria del Carmen Ricardo-Cobas, Yenima Martin-Bauta, Zadis Navarro-Rodriguez, Marjoris Pinera-Martinez, Joel Quintana-Guerra, Karen Urrutia-Perez, Klaudia Urrutia-Perez, Cristina Olimpia Chavez-Chong, Jorge Luis Azor-Hernandez, Jose Luis Rodriguez-Reinoso, Leonardo Lobaina-Lambert, Elizabeth Colina-Avila, Jacqueline Bizet-Almeida, Jeniffer Rodriguez-Nuviola, Sergio del Valle-Pinera, Mayara Ramirez-Dominguez, Elisangela Tablada-Ferreiro, Marel Alonso-Valdes, Gilda Lemos-Perez, Gerardo Enrique Guillen-Nieto, Ariel Palenzuela-Diaz, Enrique Noa-Romero, Miladys Limonta-Fernandez, Juan Manuel Fernandez-Avila, Nabil Ali-Mros, Lianne del Toro-Lahera, Rossana Remedios-Reyes, Marta Ayala-Avila, Verena Lucila Muzio-Gonzalez
medRxiv 2021.11.30.21267047; doi: https://doi.org/10.1101/2021.11.30.21267047 Revision

Third COVID-19 Vaccine Dose Boosts Neutralising Antibodies in Poor Responders
Douglas Lake, Alexa J Roeder, Maria J Gonzalez-Moa, Megan Koehler, Erin Kaleta, Paniz Jasbi, John Vanderhoof, Davis Mckechnie, Jack Forman, Baylee Edwards, Alim Seit-Nebi, Sergei Svarovsky
medRxiv 2021.11.30.21266716; doi: https://doi.org/10.1101/2021.11.30.21266716

The Politics of Vaccine Hesitancy in the United States
Jian Cao, Christina Ramirez, R. Michael Alvarez
medRxiv 2021.12.01.21267160; doi: https://doi.org/10.1101/2021.12.01.21267160

Evaluating COVID-19 booster vaccination strategies in a partially vaccinated population: a modeling study.
Clement R Massonnaud, Jonathan Roux, Vittoria Colizza, Pascal Crepey
medRxiv 2021.12.01.21267122; doi: https://doi.org/10.1101/2021.12.01.21267122

Changes Over Time in COVID-19 Vaccination Inequalities in Eight Large U.S. Cities
S. Michael Gaddis, Colleen M. Carey, Nicholas V DiRago
medRxiv 2021.12.01.21267158; doi: https://doi.org/10.1101/2021.12.01.21267158

Assessing the Burden of COVID-19 in Developing Countries: Systematic Review, Meta-Analysis, and Public Policy Implications
Andrew T Levin, Nana Owusu-Boaitey, Sierra Pugh, Bailey K Fosdick, Anthony B. Zwi, Anup Malani, Satej Soman, Lonni Besançon, Ilya Kashnitsky, Sachin Ganesh, Aloysius McLaughlin, Gayeong Song, Rine Uhm, Gideon Meyerowitz-Katz
medRxiv 2021.09.29.21264325; doi: https://doi.org/10.1101/2021.09.29.21264325

Convalescent plasma for outpatients with early COVID-19
Pere Millat-Martinez, Arvind Gharbharan, Andrea Alemany, Casper Rokx, Corine GeurtsvanKessel, Grigorios Papageourgiou, Nan van Geloven, Carlijn Jordans, Geert Groeneveld, Francis Swaneveld, Ellen van der Schoot, Marc Corbacho-Monne, Dan Ouchi, Francini Piccolo Ferreira, Pierre Malchair, Sebastian Videla, Vanesa Garcia Garcia, Anna Ruiz-Comellas, Anna Ramirez-Morros, Joana Rodriguez Codina, Rosa Amado Simon, Joan-Ramon Grifols, Julia Blanco, Ignacio Blanco, Jordi Ara, Quique Bassat, Bonaventura Clotet, Barbara Baro, Andrea Troxel, Jaap Jan Zwaginga, Oriol Mitja, Bart Rijnders
medRxiv 2021.11.30.21266810; doi: https://doi.org/10.1101/2021.11.30.21266810

Google Trends as a predictive tool for COVID-19 vaccinations in Italy: a retrospective infodemiological analysis
Alessandro Rovetta
medRxiv 2021.11.29.21267012; doi: https://doi.org/10.1101/2021.11.29.21267012

The immunogenicity and safety of different COVID-19 booster vaccination following CoronaVac or ChAdOx1 nCoV-19 primary series
Nasikarn Angkasekwinai, Suvimol Niyomnaitham, Jaturong Sewatanon, Supaporn Phumiamorn, Kasama Sukapirom, Sansnee Senawong, Surakameth Mahasirimongkol, Zheng Quan Toh, Pinklow Umrod, Thitiporn Somporn, Supaporn Chumpol, Kanokphon Ritthitham, Kulkanya Chokephaibulkit
medRxiv 2021.11.29.21266947; doi: https://doi.org/10.1101/2021.11.29.21266947

Critical success factors for routine immunization performance: A case study of Zambia 2000 to 2018
Katie Rodriguez, Kyra A. Hester, Chama Chanda, Roopa Darwar, Bonheur Dounebaine, Anna S. Ellis, Pinar Keskinocak, Abimbola Leslie, Mwangala Manyando, Maurice Sililo Manyando, Dima Nazzal, Emily Awino Ogutu, Zoe Sakas, Francisco Castillo-Zunino, William Kilembe, Robert A. Bednarczyk, Matthew C. Freeman, the Vaccine Exemplars Research Consortium
medRxiv 2021.11.30.21267060; doi: https://doi.org/10.1101/2021.11.30.21267060

Use of Artificial Intelligence on spatio-temporal data to generate insights during COVID-19 pandemic: A Review
Gihan Jayatilaka, Jameel Hassan, Umar Marikkar, Rumali Perera, Suren Sritharan, Harshana Weligampola, Mevan Ekanayake, Roshan Godaliyadda, Parakrama Ekanayake, Vijitha Herath, G M Dilshan Godaliyadda, Anuruddhika Rathnayake, Samath D. Dharmaratne, Janaka Ekanayake
medRxiv 2020.11.22.20232959; doi: https://doi.org/10.1101/2020.11.22.20232959

Wellcome Open Research [to 4 Dec 2021]
https://wellcomeopenresearch.org/browse/articles
[Accessed 4 Dec 2021]

Wellcome Open Research provides all Wellcome researchers with a place to rapidly publish any results they think are worth sharing. All articles benefit from rapid publication, transparent peer review and editorial guidance on making all source data openly available.

Research Article metrics Revised
10-year longitudinal study of malaria in children: Insights into acquisition and maintenance of naturally acquired immunity [version 2; peer review: 2 approved with reservations]
John W.G. Addy, Yaw Bediako, Francis M. Ndungu, John Joseph Valetta, Adam J. Reid, Jedida Mwacharo, Joyce Mwongeli Ngoi, Joshua Wambua, Edward Otieno, Jennifer Musyoki, Khadija Said, Matthew Berriman, Kevin Marsh, Philip Bejon, Mario Recker, Jean Langhorne
Peer Reviewers Rodrigo M Corder; Rhea J Longley
Funders: Wellcome Trust; Francis Crick Institute; Medical Research Council
LATEST VERSION PUBLISHED 03 Dec 2021

Data Note metrics Revised
The Avon Longitudinal Study of Parents and Children – A resource for COVID-19 research: Home-based antibody testing results, October 2020. An emphasis on self-screening at a population level [version 2; peer review: 1 approved, 2 approved with reservations]
Kate Northstone, Daniel Smith, Claire Bowring, Amanda Hill, Richard Hobbs, Nicholas Wells, Nicholas J. Timpson
Peer Reviewers Morteza Taheri; Jean-Luc Murk; Citra N.Z. Mattar
Funders: Wellcome Trust; Medical Research Council
LATEST VERSION PUBLISHED 02 Dec 2021

Open Letter metrics Revised
An ethical analysis of vaccinating children against COVID-19: benefits, risks, and issues of global health equity [version 2; peer review: 1 approved, 1 approved with reservations]
Rachel Gur-Arie, Steven R. Kraaijeveld, Euzebiusz Jamrozik
Peer Reviewers Stefan David Baral; Tracy Beth Høeg
Funders: Wellcome Trust; ZonMw
LATEST VERSION PUBLISHED 29 Nov 2021
Abstract
COVID-19 vaccination of children has begun in various high-income countries with regulatory approval and general public support, but largely without careful ethical consideration. This trend is expected to extend to other COVID-19 vaccines and lower ages as clinical trials progress. This paper provides an ethical analysis of COVID-19 vaccination of healthy children. Specifically, we argue that it is currently unclear whether routine COVID-19 vaccination of healthy children is ethically justified in most contexts, given the minimal direct benefit that COVID-19 vaccination provides to children, the potential for rare risks to outweigh these benefits and undermine vaccine confidence, and substantial evidence that COVID-19 vaccination confers adequate protection to risk groups, such as older adults, without the need to vaccinate healthy children. We conclude that child COVID-19 vaccination in wealthy communities before adults in poor communities worldwide is ethically unacceptable and consider how policy deliberations might evolve in light of future developments.