Maternal and neonatal data collection systems in low- and middle-income countries for maternal vaccines active safety surveillance systems: A scoping review

BMC Pregnancy and Childbirth
http://www.biomedcentral.com/bmcpregnancychildbirth/content
(Accessed 20 Mar 2021)

 

Maternal and neonatal data collection systems in low- and middle-income countries for maternal vaccines active safety surveillance systems: A scoping review
Most post-licensure vaccine pharmacovigilance in low- and middle-income countries (LMICs) are passive reporting systems. These have limited utility for maternal immunization pharmacovigilance in LMIC settings …
Authors: Mabel Berrueta, Agustin Ciapponi, Ariel Bardach, Federico Rodriguez Cairoli, Fabricio J. Castellano, Xu Xiong, Andy Stergachis, Sabra Zaraa, Ajoke Sobanjo-ter Meulen and Pierre Buekens
Citation: BMC Pregnancy and Childbirth 2021 21:217
Content type: Research article
Published on: 17 March 2021

Factors associated with measles vaccination status in children under the age of three years in a post-soviet context: a cross-sectional study using the DHS VII in Armenia

BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 20 Mar 2021)

 

Factors associated with measles vaccination status in children under the age of three years in a post-soviet context: a cross-sectional study using the DHS VII in Armenia
The resurgence of measles globally and the increasing number of unvaccinated clusters call for studies exploring factors that influence measles vaccination uptake. Armenia is a middle-income post-Soviet countr…
Authors: Annabell C. Kantner, Sibylle Herzig van Wees, Erik M. G. Olsson and Shirin Ziaei
Citation: BMC Public Health 2021 21:552
Content type: Research article
Published on: 20 March 2021

Determinants of influenza vaccine uptake and willingness to be vaccinated by pharmacists among the active adult population in Hungary: a cross-sectional exploratory study

BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 20 Mar 2021)

 

Determinants of influenza vaccine uptake and willingness to be vaccinated by pharmacists among the active adult population in Hungary: a cross-sectional exploratory study
Many studies have addressed influenza vaccine uptake in risk-group populations (e.g. the elderly). However, it is also necessary to assess influenza vaccine uptake in the active adult population, since they ar…
Authors: Githa Fungie Galistiani, Mária Matuz, Nikolett Matuszka, Péter Doró, Krisztina Schváb, Zsófia Engi and Ria Benkő
Citation: BMC Public Health 2021 21:521
Content type: Research article
Published on: 17 March 2021

Differences between Frequentist and Bayesian inference in routine surveillance for influenza vaccine effectiveness: a test-negative case-control study

BMC Public Health
http://bmcpublichealth.biomedcentral.com/articles
(Accessed 20 Mar 2021)

 

Differences between Frequentist and Bayesian inference in routine surveillance for influenza vaccine effectiveness: a test-negative case-control study
Routine influenza vaccine effectiveness (VE) surveillance networks use frequentist methods to estimate VE. With data from more than a decade of VE surveillance from diverse global populations now available, us…
Authors: Michael L. Jackson, Jill Ferdinands, Mary Patricia Nowalk, Richard K. Zimmerman, Burney Kieke, Manjusha Gaglani, Kempapura Murthy, Joshua G. Petrie, Emily T. Martin, Jessie R. Chung, Brendan Flannery and Lisa A. Jackson
Citation: BMC Public Health 2021 21:516
Content type: Research article
Published on: 16 March 2021

The ethical scientist in a time of uncertainty

Cell
Mar 18, 2021 Volume 184 Issue 6 p1395-1650
https://www.cell.com/cell/issue?pii=S0092-8674(20)X0007-9

 

Perspectives
Featured Article
The ethical scientist in a time of uncertainty
Laurie Zoloth
Summary
All of science takes place amidst a world shaken by uncertainty, social and political upheaval, and challenges to truthful testimony. Just at the moment in which increasing control over biology has been theorized, our social world has become increasingly contentious and its values more divisive. Using the example of gene drives for malaria control to explore the problem of deep uncertainty in biomedical research, I argue that profound uncertainty is an essential feature. Applying the language and presumptions of the discipline of philosophical ethics, I describe three types of uncertainty that raise ethical challenges in scientific research. Rather than mitigate these challenges with excessive precautions and limits on progress, I suggest that researchers can cultivate classic values of veracity, courage, humility, and fidelity in their research allowing science to proceed ethically under conditions of deep uncertainty.

Heritable human genome editing: Research progress, ethical considerations, and hurdles to clinical practice

Cell
Mar 18, 2021 Volume 184 Issue 6 p1395-1650
https://www.cell.com/cell/issue?pii=S0092-8674(20)X0007-9

 

Heritable human genome editing: Research progress, ethical considerations, and hurdles to clinical practice
Jenna Turocy, Eli Y. Adashi, Dieter Egli
Our genomes at conception contribute substantially to our overall health, and heritable genome editing could provide many benefits by preventing disease from the beginning of life. Egli and colleagues review the scientific contributions to the field, the ethical challenges that cannot be overlooked, and the hurdles to be overcome prior to clinical practice.

Novel approaches for vaccine development

Cell
Mar 18, 2021 Volume 184 Issue 6 p1395-1650
https://www.cell.com/cell/issue?pii=S0092-8674(20)X0007-9

 

Novel approaches for vaccine development
Makda S. Gebre, Luis A. Brito, Lisa H. Tostanoski, Darin K. Edwards, Andrea Carfi, Dan H. Barouch
Vaccines play a critical role in global health, and Gebre et al. review the current state of three vaccine development platforms (mRNA vaccines, vector-based vaccines, and materials science approaches to vaccination).

Decoding Covid-19 with the SARS-CoV-2 Genome

Current Genetic Medicine Reports
Volume 9, issue 1, March 2021
https://link.springer.com/journal/40142/volumes-and-issues/9-1

 

Bioinformatics (A Pittman, Section Editor)
Decoding Covid-19 with the SARS-CoV-2 Genome
Authors (first, second and last of 5)
Phoebe Ellis, Ferenc Somogyvári, Gary R. McLean
Published: 09 January 2021
Pages: 1 – 12
SARS-CoV-2, the recently emerged coronavirus (CoV) that is responsible for the current global pandemic Covid-19, first appeared in late 2019 in Wuhan, China. Here, we summarise details of the SARS-CoV-2 genome to assist understanding of the emergence, evolution and diagnosis of this deadly new virus.

The Ethics of Repurposing Previously Collected Research Biospecimens in an Infectious Disease Pandemic

Ethics & Human Research
Volume 43, Issue 2 Pages: 1-48 March–April 2021
https://onlinelibrary.wiley.com/toc/25782363/current

 

Research ethics and pandemics • IRBs and AI research
Articles
Free Access
The Ethics of Repurposing Previously Collected Research Biospecimens in an Infectious Disease Pandemic
Benjamin E. Berkman et al
Pages: 2-18
First Published: 23 February 2021

Governing AI‐Driven Health Research: Are IRBs Up to the Task?

Ethics & Human Research
Volume 43, Issue 2 Pages: 1-48 March–April 2021
https://onlinelibrary.wiley.com/toc/25782363/current

 

Articles
Governing AI‐Driven Health Research: Are IRBs Up to the Task?
Phoebe Friesen, et al.
Pages: 35-42
First Published: 08 March 2021
ABSTRACT
Many are calling for concrete mechanisms of oversight for health research involving artificial intelligence (AI). In response, institutional review boards (IRBs) are being turned to as a familiar model of governance. Here, we examine the IRB model as a form of ethics oversight for health research that uses AI. We consider the model’s origins, analyze the challenges IRBs are facing in the contexts of both industry and academia, and offer concrete recommendations for how these committees might be adapted in order to provide an effective mechanism of oversight for health‐related AI research.

Supporting communities of practice – A Journey to effective problem-solving

Gates Open Research
https://gatesopenresearch.org/browse/articles
[Accessed 20 Mar 2021]

 

Open Letter metrics
Revised
Supporting communities of practice – A Journey to effective problem-solving [version 2; peer review: 2 approved with reservations, 1 not approved]
Christina Hanschke, James Baer, Alok Gangaramany, Janneke Verheijen, Nduku Kilonzo, Bryan Okiya, Leonard Kibe Ranji, Stephen Amolo Amolo, Simon Zwane, Rejoice Nkambule, Violet Buluma, Sylvia Ojoo, Susan Kim, Sharon Kibwana, Mark Dybul, Steve Kretschmer
Peer Reviewers Carlos Toledo; Julia Samuelson; Tracy Johnson
Funder: Bill and Melinda Gates Foundation
LATEST VERSION PUBLISHED 16 Mar 2021
Abstract
In contexts of scarce resources, varied assets, and diverse communities, engaging local stakeholders in the problem-solving process is critical to develop interventions for HIV prevention and treatment. Communities of practice (CoPs) – groups of people organized around a key purpose and a delivery point – can develop expertise in identifying their local community’s key challenges and selecting viable solutions. We propose a framework, adapted from the CoP model developed by Etienne Wenger, for systematically understanding the stages a CoP may go through as it develops its capacity to identify and solve problems and implement good practices.

Countries with delayed COVID-19 introduction – characteristics, drivers, gaps, and opportunities

Globalization and Health
http://www.globalizationandhealth.com/
[Accessed 20 Mar 2021]

 

Countries with delayed COVID-19 introduction – characteristics, drivers, gaps, and opportunities
Authors: Zheng Li, Cynthia Jones, Girum S. Ejigu, Nisha George, Amanda L. Geller, Gregory C. Chang, Alys Adamski, Ledor S. Igboh, Rebecca D. Merrill, Philip Ricks, Sara A. Mirza and Michael Lynch
Content type: Research
17 March 2021
…This analysis aimed to 1) assess characteristics, capability to detect and monitor COVID-19, and disease control measures in these 24 countries, 2) understand potential factors for the reported delayed COVID-19 introduction, and 3) identify gaps and opportunities for outbreak preparedness, particularly in low and middle-income countries (LMICs). We collected and analyzed publicly available information on country characteristics, COVID-19 testing, influenza surveillance, border measures, and preparedness activities in these countries. We also assessed the association between the temporal spread of COVID-19 in all countries with reported cases with globalization indicator and geographic location.

Disability inclusion in humanitarian action

Humanitarian Exchange Magazine
Number 78, October 2020
https://odihpn.org/magazine/inclusion-of-persons-with-disabilities-in-humanitarian-action-what-now/

 

Disability inclusion in humanitarian action
by HPN October 2020
The theme of this edition of Humanitarian Exchange, co-edited with Sherin Alsheikh Ahmed from Islamic Relief Worldwide, is disability inclusion in humanitarian action. Persons with disabilities are not only disproportionately impacted by conflicts, disasters and other emergencies, but also face barriers to accessing humanitarian assistance. At the same time, global commitments and standards and the IASC Guidelines on the inclusion of persons with disabilities in humanitarian action all emphasise how persons with disabilities are also active agents of change. Disability and age-focused organisations have led on testing and demonstrating how inclusion can be done better. Yet despite this progress, challenges to effective inclusion remain.

As Kirstin Lange notes in the lead article, chief among these challenges is humanitarian agencies’ lack of engagement with organisations of persons with disabilities. Simione Bula, Elizabeth Morgan and Teresa Thomson look at disability inclusion in humanitarian response in the Pacific, and Kathy Al Jubeh and Alradi Abdalla argue for a ‘participation revolution’, building on learning from the gender movement. Tchaurea Fleury and Sulayman AbdulMumuni Ujah outline how the Bridge Article 11 training initiative is encouraging constructive exchange between humanitarian and disability actors. The lack of good, disaggregated data is highlighted by Sarah Collinson; Frances Hill, Jim Cranshaw and Carys Hughes emphasise the need for training resources in local languages and accessible formats; and Sophie Van Eetvelt and colleagues report on a review of the evidence on inclusion of people with disabilities and older people.

Rebecca Molyneux and co-authors analyse the findings of a review of a DFID programme in north-east Nigeria, while Carolin Funke highlights the importance of strategic partnerships between disability-focused organisations, drawing on her research in Cox’s Bazar. Sherin Alsheikh Ahmed describes Islamic Relief Worldwide’s approach to mainstreaming protection and inclusion, while Pauline Thivillier and Valentina Shafina outline IRC’s Client Responsive Programming. The edition ends with reflections by Mirela Turcanu and Yves Ngunzi Kahashi on CAFOD’s SADI approach.

Leveraging on the genomics and immunopathology of SARS-CoV-2 for vaccines development: prospects and challenges

Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 3, 2021
https://www.tandfonline.com/toc/khvi20/current

 

Review
Leveraging on the genomics and immunopathology of SARS-CoV-2 for vaccines development: prospects and challenges
Idris Nasir Abdullahi, et al
Pages: 620-637
Published online: 16 Sep 2020

COVID-19 outbreak: a potential threat to routine vaccination programme activities in Nigeria

Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 3, 2021
https://www.tandfonline.com/toc/khvi20/current

 

article commentary
COVID-19 outbreak: a potential threat to routine vaccination programme activities in Nigeria
Olorunfemi Akinbode Ogundele, Ayodeji Andrew Omotoso & Aderonke Tolulope Fagbemi
Pages: 661-663
Published online: 29 Sep 2020

Modelling of optimal vaccination strategies in response to a bioterrorism associated smallpox outbreak

Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 3, 2021
https://www.tandfonline.com/toc/khvi20/current

 

Article
Modelling of optimal vaccination strategies in response to a bioterrorism associated smallpox outbreak
Valentina Costantino, Mohana Kunasekaran & Chandini Raina MacIntyre
Pages: 738-746
Published online: 02 Dec 2020

Hypothetical assessment of efficiency, willingness-to-accept and willingness-to-pay for dengue vaccine and treatment: a contingent valuation survey in Bangladesh

Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 3, 2021
https://www.tandfonline.com/toc/khvi20/current

 

Article
Hypothetical assessment of efficiency, willingness-to-accept and willingness-to-pay for dengue vaccine and treatment: a contingent valuation survey in Bangladesh
K M Ariful Kabir, Aya Hagishima & Jun Tanimoto
Pages: 773-784
Published online: 21 Aug 2020

Knowledge, attitude, perception of Muslim parents towards vaccination in Malaysia

Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 3, 2021
https://www.tandfonline.com/toc/khvi20/current

 

Article
Knowledge, attitude, perception of Muslim parents towards vaccination in Malaysia
Mohammed Tahir Ansari, Nurul Nadia Jamaluddin, Thiya Anissa Ramlan, Nurshahiera Zamri, Shahnaz Majeed, Vishal Badgujar, Farheen Sami, M Saquib Hasnain & Helvinder Kaur Balbir Singh
Pages: 785-790
Published online: 24 Aug 2020

Human papillomavirus vaccination: coverage rate, knowledge, acceptance, and associated factors in college students in mainland China

Human Vaccines & Immunotherapeutics (formerly Human Vaccines)
Volume 17, Issue 3, 2021
https://www.tandfonline.com/toc/khvi20/current

 

Article
Human papillomavirus vaccination: coverage rate, knowledge, acceptance, and associated factors in college students in mainland China
Che Deng, Xiaoli Chen & Yanqun Liu
Pages: 828-835
Published online: 01 Sep 2020

COVID-19 Vaccination in Pregnant and Lactating Women

JAMA
March 16, 2021, Vol 325, No. 11, Pages 1025-1118
https://jamanetwork.com/journals/jama/currentissue

 

Viewpoint
COVID-19 Vaccination in Pregnant and Lactating Women
Emily H. Adhikari, MD; Catherine Y. Spong, MD
free access has active quiz has multimedia has audio
JAMA. 2021;325(11):1039-1040. doi:10.1001/jama.2021.1658
This Viewpoint discusses the need for shared decision-making when counseling pregnant and nursing women about the unstudied benefits and risks COVID-19 vaccination, calling for rigorously designed studies with real-time, proactive data collection to establish evidence as quickly as possible about coronavirus vaccine safety in mothers and their infants.

Conversations with Dr Bauchner: Coronavirus Vaccination in Pregnant and Breastfeeding Individuals

Protecting Pregnant Women and Their Infants From COVID-19: Clues From Maternal Viral Loads, Antibody Responses, and Placentas

JAMA
March 16, 2021, Vol 325, No. 11, Pages 1025-1118
https://jamanetwork.com/journals/jama/currentissue

 

Invited Commentary
Protecting Pregnant Women and Their Infants From COVID-19: Clues From Maternal Viral Loads, Antibody Responses, and Placentas
Denise J. Jamieson, MD, MPH; Sonja A. Rasmussen, MD, MS

Involving Pregnant Individuals in Clinical Research on COVID-19 Vaccines

JAMA
March 16, 2021, Vol 325, No. 11, Pages 1025-1118
https://jamanetwork.com/journals/jama/currentissue

 

Involving Pregnant Individuals in Clinical Research on COVID-19 Vaccines
Diana W. Bianchi, MD; Lisa Kaeser, JD; Alison N. Cernich, PhD
free access has multimedia has audio
JAMA. 2021;325(11):1041-1042. doi:10.1001/jama.2021.1865
This Viewpoint from the National Institute of Child Health and Human Development emphasizes the need to use existing data sources and develop partnerships, infrastructure, and ethical and regulatory standards to generate data about the safety and efficacy of COVID-19 vaccination in pregnant individuals.

Pregnancy, Postpartum Care, and COVID-19 Vaccination in 2021

JAMA
March 16, 2021, Vol 325, No. 11, Pages 1025-1118
https://jamanetwork.com/journals/jama/currentissue

 

Women’s Health
Pregnancy, Postpartum Care, and COVID-19 Vaccination in 2021
Sonja A. Rasmussen, MD, MS; Denise J. Jamieson, MD, MPH
free access has active quiz has multimedia has audio
JAMA. 2021;325(11):1099-1100. doi:10.1001/jama.2021.1683
This JAMA Insights review summarizes the epidemiology of SARS-CoV-2 infection in pregnant and lactating women, its effects on perinatal outcomes, and compiles guidance from the CDC, FDA, and obstetrics-gynecology specialty organizations on the safety of coronavirus vaccines during pregnancy and while breastfeeding.

Reports of Anaphylaxis After Receipt of mRNA COVID-19 Vaccines in the US—December 14, 2020-January 18, 2021

JAMA
March 16, 2021, Vol 325, No. 11, Pages 1025-1118
https://jamanetwork.com/journals/jama/currentissue

 

Reports of Anaphylaxis After Receipt of mRNA COVID-19 Vaccines in the US—December 14, 2020-January 18, 2021
Tom T. Shimabukuro, MD, MPH, MBA; Matthew Cole, MPH; John R. Su, MD, PhD, MPH
free access has active quiz has multimedia has audio
JAMA. 2021;325(11):1101-1102. doi:10.1001/jama.2021.1967
This JAMA Insights review provides clinical details of anaphylactic reactions reported to and verified by the CDC in the first month of use of the Pfizer-BioNTech and Moderna COVID-19 vaccines in the US, December 14, 2020-January 18, 2021.

The Search for an HIV Cure: Where Do We Go From Here?

Journal of Infectious Diseases
Volume 223, Issue Supplement_1, 1 February 2021
https://academic.oup.com/jid/issue/223/Supplement_1

 

SUPPLEMENT – Challenges and Promising Approaches for HIV Remission
Articles
The Search for an HIV Cure: Where Do We Go From Here?
Jonathan Z Li, Rajesh T Gandhi
The Journal of Infectious Diseases, Volume 223, Issue Supplement_1, 1 February 2021, Pages S1–S3, https://doi.org/10.1093/infdis/jiaa738

Scientific interactions in a virtual world

Nature Human Behaviour
Volume 5 Issue 3, March 2021
https://www.nature.com/nathumbehav/volumes/5/issues/3

 

Editorial | 19 March 2021
Scientific interactions in a virtual world
COVID-19 has forced a rethink of many practices we previously took for granted, and academic travel is no exception. Virtual conferences have demonstrated their promise for encouraging a more equitable and environmentally friendly future.

Changing scientific meetings for the better

Nature Human Behaviour
Volume 5 Issue 3, March 2021
https://www.nature.com/nathumbehav/volumes/5/issues/3

 

Comment | 15 March 2021
Changing scientific meetings for the better
Conferences are a pivotal part of the scientific enterprise, but large in-person meetings have several disadvantages. As the pandemic experience has shown, online meetings are a viable alternative. Accelerating efforts to improve conferences in virtual formats can lead to a more equitable and sustainable conference culture.
Sarvenaz Sarabipour, Aziz Khan  & Tomislav Mestrovic

Promoting diagnostics as a global good

Nature Medicine
Volume 27 Issue 3, March 2021
https://www.nature.com/nm/volumes/27/issues/3

 

Comment | 15 March 2021
Promoting diagnostics as a global good
The COVID-19 pandemic has reasserted the central role of effective diagnostics in the response to outbreaks. But a lack of coordination still hampers widespread access to these critical tools. A diagnostics agenda for global health is urgently needed for the promotion of diagnostics as a global good and to ensure their delivery.
Catharina Boehme, Emma Hannay  & Madhukar Pai

Beyond recruitment: good participatory practice enhances the impact of research in a pandemic

Nature Medicine
Volume 27 Issue 3, March 2021
https://www.nature.com/nm/volumes/27/issues/3

 

Comment | 15 March 2021
Beyond recruitment: good participatory practice enhances the impact of research in a pandemic
In a health emergency, clear, two-way communication between researchers and a broad spectrum of stakeholders is essential to establishing trust—a prerequisite for meaningful uptake of new treatments and vaccines.
Barthalomew Wilson, Katharine Wright & Elizabeth Higgs

Developing therapeutic approaches for twenty-first-century emerging infectious viral diseases

Nature Medicine
Volume 27 Issue 3, March 2021
https://www.nature.com/nm/volumes/27/issues/3

 

Review Article | 15 March 2021
Developing therapeutic approaches for twenty-first-century emerging infectious viral diseases
As the emergence of viral diseases is expected to accelerate, proactive programs to develop broadly active family-specific and cross-family antiviral therapeutics will be key to prepare for future disease outbreaks.
Rita M. Meganck & Ralph S. Baric

A systematic review on improving implementation of the revitalised integrated disease surveillance and response system in the African region: A health workers’ perspective

PLoS One
http://www.plosone.org/
[Accessed 20 Mar 2021]

 

A systematic review on improving implementation of the revitalised integrated disease surveillance and response system in the African region: A health workers’ perspective
Arthur K. S. Ng’etich, Kuku Voyi, Ruth C. Kirinyet, Clifford M. Mutero
Research Article | published 19 Mar 2021 PLOS ONE
https://doi.org/10.1371/journal.pone.0248998

Vaccinating the oldest against COVID-19 saves both the most lives and most years of life

PNAS – Proceedings of the National Academy of Sciences of the United States of America
March 16, 2021; vol. 118 no. 11
https://www.pnas.org/content/118/11

 

Brief Report Open Access
Vaccinating the oldest against COVID-19 saves both the most lives and most years of life
Joshua R. Goldstein, Thomas Cassidy, and Kenneth W. Wachter
PNAS March 16, 2021 118 (11) e2026322118; https://doi.org/10.1073/pnas.20263221

The right to health, public health and COVID-19: a discourse on the importance of the enforcement of humanitarian and human rights law in conflict settings for the future management of zoonotic pandemic diseases

Public Health
Volume 192 Pages 1-74 (March 2021)
https://www.sciencedirect.com/journal/public-health/vol/192/suppl/C

 

Review article Full text access
The right to health, public health and COVID-19: a discourse on the importance of the enforcement of humanitarian and human rights law in conflict settings for the future management of zoonotic pandemic diseases
M.C. Van Hout, J.S.G. Wells
Pages 3-7
Abstract
Objectives
The catastrophic effects of armed conflict, particularly prolonged armed conflict, on individual and public health are well established. The ‘right’ to healthcare during armed conflict and its lack of enforcement despite a range of United Nations mandated requirements regarding health and healthcare provisions is likely to be a significant feature in future conflicts, as zoonotic-induced pandemics become a more common global public health challenge. The issue of enforcement of health rights assurance and its implications for the public health management of global pandemics such as coronavirus disease 2019 (COVID-19) in and between countries and regions in conflict is the objective of this Review.

Justice, diversity, and research ethics review

Science
19 March 2021 Vol 371, Issue 6535
http://www.sciencemag.org/current.dtl

 

Policy Forum
Justice, diversity, and research ethics review
By David H. Strauss, Sarah A. White, Barbara E. Bierer
Science19 Mar 2021 : 1209-1211 Full Access
It is time for institutional review boards and research ethics committees to address the ethics of inclusion
Summary
The disproportionate impact of COVID-19 on certain populations, such as Black, Latinx, and Indigenous populations in the United States, has focused attention on inequalities in health and on the need to increase enrollment of racial and ethnic minorities and other underrepresented groups in biomedical research (1). Yet too often, in the United States and globally, participant enrollment in research has not reflected the demographic composition of the general population, those affected by the health conditions being studied, or those for whom the investigational product is intended (2), with racial and ethnic minorities and the young and the elderly, among others, being consistently underrepresented (3). Underlying causes for this underrepresentation have been described (4, 5), but change has been slow. Notwithstanding the roles of other stakeholders in addressing this issue, we maintain that the specific value of institutional review boards (IRBs) and research ethics committees (RECs) in promoting diversity has been underrecognized and their authority underutilized. Here, we substantiate the role of and outline practical steps for the IRB and REC (hereafter “IRB”) to help achieve greater diversity in clinical research.

Sex difference in the immunogenicity of the quadrivalent Human Papilloma Virus vaccine: Systematic review and meta-analysis

Vaccine
Volume 39, Issue 12 Pages 1667-1796 (19 March 2021)
https://www.sciencedirect.com/journal/vaccine/vol/39/issue/12

 

Review article Open access
Sex difference in the immunogenicity of the quadrivalent Human Papilloma Virus vaccine: Systematic review and meta-analysis
Lafi Aldakak, Vera Maria Huber, Frank Rühli, Nicole Bender
Pages 1680-1686

Perspectives on the receipt of a COVID-19 vaccine: A survey of employees in two large hospitals in Philadelphia

Vaccine
Volume 39, Issue 12 Pages 1667-1796 (19 March 2021)
https://www.sciencedirect.com/journal/vaccine/vol/39/issue/12

 

Research article Full text access
Perspectives on the receipt of a COVID-19 vaccine: A survey of employees in two large hospitals in Philadelphia
Barbara J. Kuter, Safa Browne, Florence M. Momplaisir, Kristen A. Feemster, … Paul A. Offit
Pages 1693-1700
Health care personnel have been identified by the ACIP as a priority group for COVID-19 vaccination. We conducted a survey in November-December 2020 at two large, academic hospitals in Philadelphia to evaluate the intention of hospital employees to be vaccinated.

Estimating pneumococcal vaccine coverage among Australian Indigenous children and children with medically at-risk conditions using record linkage

Vaccine
Volume 39, Issue 12 Pages 1667-1796 (19 March 2021)
https://www.sciencedirect.com/journal/vaccine/vol/39/issue/12

 

Research article Abstract only
Estimating pneumococcal vaccine coverage among Australian Indigenous children and children with medically at-risk conditions using record linkage
Alamgir Kabir, Anthony T. Newall, Deborah Randall, Rob Menzies, … Heather F. Gidding
Pages 1727-1735

Improving adolescent human papillomavirus (HPV) immunization uptake in school-based health centers through awareness campaigns

Vaccine
Volume 39, Issue 12 Pages 1667-1796 (19 March 2021)
https://www.sciencedirect.com/journal/vaccine/vol/39/issue/12

 

Research article Abstract only
Improving adolescent human papillomavirus (HPV) immunization uptake in school-based health centers through awareness campaigns
Madhura S. Rane, Libby C. Page, Emma McVeigh, Kaetlin Miller, … Jeffrey S. Duchin
Pages 1765-1772

The Impact of a Single Educational Lecture on the Vaccine Confidence among Pregnant Women and Young Mothers

Vaccines — Open Access Journal
http://www.mdpi.com/journal/vaccines
(Accessed 20 Mar 2021)

 

Open Access Article
The Impact of a Single Educational Lecture on the Vaccine Confidence among Pregnant Women and Young Mothers
by Katarzyna Tkaczyszyn et al
Vaccines 2021, 9(3), 290; https://doi.org/10.3390/vaccines9030290 (registering DOI) – 20 Mar 2021
Abstract
Background: We investigated the impact of a single unstructured educational lecture about vaccinations on the vaccine confidence in volunteer participants. Methods: We conducted a survey-based study during a series of open meetings related to pregnancy and parenting. Before and after the pediatrician’s lecture […]