Nature Reviews Genetics
Volume 23 Issue 5, May 2022
Review Article | 08 December 2021
Computational analysis of cancer genome sequencing data
In this Review the authors provide an overview of key algorithmic developments, popular tools and emerging technologies used in the bioinformatic analysis of genomes. They also describe how such analysis can identify point mutations, copy number alterations, structural variations and mutational signatures in cancer genomes.
Isidro Cortés-Ciriano, Doga C. Gulhan, Peter J. Park