Nature Reviews Immunology
Volume 22 Issue 5, May 2022
https://www.nature.com/nri/volumes/22/issues/5

Comment | 12 April 2022
Estimating disease severity of Omicron and Delta SARS-CoV-2 infections
The Omicron variant of SARS-CoV-2 has been reported to cause milder disease in adults but lead to increased hospital admissions in children. How can we compare disease severity in Omicron and Delta infections, and how should differences be interpreted?
Alex Sigal, Ron Milo, Waasila Jassat