May 12, 2022 Volume 185 Issue 10 p1619-1806
Precision medicine requires understanding how both sex and gender influence health
Nina S. Stachenfeld, Carolyn M. Mazure
Progress in studying sex as a biological variable (SABV) is slow, and the influence of gendered effects of the social environment on biology is largely unknown. Yet incorporating these concepts into basic science research will enhance our understanding human health and disease. We provide steps to move this process forward.