National tuberculosis spending efficiency and its associated factors in 121 low-income and middle-income countries, 2010–19: a data envelopment and stochastic frontier analysis

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Lancet Global Health
Apr 2022 Volume 10 Number 4 e448-e584
https://www.thelancet.com/journals/langlo/issue/current

 

Articles
National tuberculosis spending efficiency and its associated factors in 121 low-income and middle-income countries, 2010–19: a data envelopment and stochastic frontier analysis
Gerard Joseph Abou Jaoude, et al.

The Lancet Global Health Commission on financing primary health care: putting people at the centre

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Lancet Global Health
Apr 2022 Volume 10 Number 4 e448-e584
https://www.thelancet.com/journals/langlo/issue/current

 

The Lancet Global Health Commissions
The Lancet Global Health Commission on financing primary health care: putting people at the centre
Kara Hanson, et al
The COVID-19 pandemic has brought the need for well-functioning primary health care (PHC) into sharp focus. PHC is the best platform for providing basic health interventions (including effective management of non-communicable diseases) and essential public health functions. PHC is widely recognised as a key component of all high-performing health systems and is an essential foundation of universal health coverage

Measuring the effects of COVID-19-related disruption on dengue transmission in southeast Asia and Latin America: a statistical modelling study

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Lancet Infectious Diseases
May 2022 Volume 22 Number 5 p563-742, e128-e158
https://www.thelancet.com/journals/laninf/issue/current

 

Articles
Measuring the effects of COVID-19-related disruption on dengue transmission in southeast Asia and Latin America: a statistical modelling study
Yuyang Chen, et al. on behalf of the CMMID COVID-19 Working Group
Open Access

Neonatal rotavirus vaccine (RV3-BB) immunogenicity and safety in a neonatal and infant administration schedule in Malawi: a randomised, double-blind, four-arm parallel group dose-ranging study

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Lancet Infectious Diseases
May 2022 Volume 22 Number 5 p563-742, e128-e158
https://www.thelancet.com/journals/laninf/issue/current

 

Neonatal rotavirus vaccine (RV3-BB) immunogenicity and safety in a neonatal and infant administration schedule in Malawi: a randomised, double-blind, four-arm parallel group dose-ranging study
Desiree Witte, et al.

Measuring the effects of COVID-19-related disruption on dengue transmission in southeast Asia and Latin America: a statistical modelling study

Posted on by

Lancet Infectious Diseases
May 2022 Volume 22 Number 5 p563-742, e128-e158
https://www.thelancet.com/journals/laninf/issue/current

 

Measuring the effects of COVID-19-related disruption on dengue transmission in southeast Asia and Latin America: a statistical modelling study
Yuyang Chen, et al. on behalf of the CMMID COVID-19 Working Group
Open Access

Neonatal rotavirus vaccine (RV3-BB) immunogenicity and safety in a neonatal and infant administration schedule in Malawi: a randomised, double-blind, four-arm parallel group dose-ranging study

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Lancet Infectious Diseases
May 2022 Volume 22 Number 5 p563-742, e128-e158
https://www.thelancet.com/journals/laninf/issue/current

 

Neonatal rotavirus vaccine (RV3-BB) immunogenicity and safety in a neonatal and infant administration schedule in Malawi: a randomised, double-blind, four-arm parallel group dose-ranging study
Desiree Witte, et al.

Estimating the effect of vaccination on antimicrobial-resistant typhoid fever in 73 countries supported by Gavi: a mathematical modelling study

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Lancet Infectious Diseases
May 2022 Volume 22 Number 5 p563-742, e128-e158
https://www.thelancet.com/journals/laninf/issue/current

 

Estimating the effect of vaccination on antimicrobial-resistant typhoid fever in 73 countries supported by Gavi: a mathematical modelling study
Ruthie Birger, et al.

Using big data and mobile health to manage diarrhoeal disease in children in low-income and middle-income countries: societal barriers and ethical implications

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Lancet Infectious Diseases
May 2022 Volume 22 Number 5 p563-742, e128-e158
https://www.thelancet.com/journals/laninf/issue/current

 

Series
Combating Childhood Infections in LMICs: Evaluating the Contribution of Big Data
Using big data and mobile health to manage diarrhoeal disease in children in low-income and middle-income countries: societal barriers and ethical implications
Karen H Keddy, et al.

Non-typeable Haemophilus influenzae–Moraxella catarrhalis vaccine for the prevention of exacerbations in chronic obstructive pulmonary disease: a multicentre, randomised, placebo-controlled, observer-blinded, proof-of-concept, phase 2b trial

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Lancet Respiratory Medicine
May 2022 Volume 10 Number 5 p421-524, e44-e50
https://www.thelancet.com/journals/lanres/issue/current

 

Articles
Non-typeable Haemophilus influenzae–Moraxella catarrhalis vaccine for the prevention of exacerbations in chronic obstructive pulmonary disease: a multicentre, randomised, placebo-controlled, observer-blinded, proof-of-concept, phase 2b trial
Stefan Andreas,et al. on behalf of the NTHi-Mcat-002 study group

Drug delivery systems for RNA therapeutics

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Nature Reviews Genetics
Volume 23 Issue 5, May 2022
https://www.nature.com/nrg/volumes/23/issues/5

 

Review Article | 04 January 2022
Drug delivery systems for RNA therapeutics
RNA therapies can be used to manipulate gene expression or produce therapeutic proteins. Here, the authors describe the growing number of RNA therapies and their molecular mechanisms of action. They also discuss the path from preclinical drug delivery research to clinical approval of these drugs.
Kalina Paunovska, David Loughrey, James E. Dahlman

Computational analysis of cancer genome sequencing data

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Nature Reviews Genetics
Volume 23 Issue 5, May 2022
https://www.nature.com/nrg/volumes/23/issues/5

 

Review Article | 08 December 2021
Computational analysis of cancer genome sequencing data
In this Review the authors provide an overview of key algorithmic developments, popular tools and emerging technologies used in the bioinformatic analysis of genomes. They also describe how such analysis can identify point mutations, copy number alterations, structural variations and mutational signatures in cancer genomes.
Isidro Cortés-Ciriano, Doga C. Gulhan, Peter J. Park

Estimating disease severity of Omicron and Delta SARS-CoV-2 infections

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Nature Reviews Immunology
Volume 22 Issue 5, May 2022
https://www.nature.com/nri/volumes/22/issues/5

 

Comment | 12 April 2022
Estimating disease severity of Omicron and Delta SARS-CoV-2 infections
The Omicron variant of SARS-CoV-2 has been reported to cause milder disease in adults but lead to increased hospital admissions in children. How can we compare disease severity in Omicron and Delta infections, and how should differences be interpreted?
Alex Sigal, Ron Milo, Waasila Jassat

SARS-CoV-2 infection and COVID-19 vaccination in pregnancy

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Nature Reviews Immunology
Volume 22 Issue 5, May 2022
https://www.nature.com/nri/volumes/22/issues/5

 

Progress | 18 March 2022
SARS-CoV-2 infection and COVID-19 vaccination in pregnancy
In this Progress article, Male summarizes our current understanding of the risks associated with SARS-CoV-2 infection in pregnancy. Importantly, the article highlights the now substantial body of evidence supporting the safety and efficacy of COVID-19 vaccination in pregnancy.
Victoria Male

Research on rare diseases: ten years of progress and challenges at IRDiRC

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Nature Reviews Drug Discovery
Volume 21 Issue 5, May 2022
https://www.nature.com/nrd/volumes/21/issues/5

 

Comment | 25 January 2022
Research on rare diseases: ten years of progress and challenges at IRDiRC
The International Rare Diseases Research Consortium (IRDiRC) is a global collaborative initiative launched in 2011, aimed at tackling rare diseases through research. Here, we summarize IRDiRC’s vision and goals and highlight achievements and prospects after its first decade.
Lucia Monaco, Galliano Zanello, David A. Pearce

Strategies to access biosynthetic novelty in bacterial genomes for drug discovery

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Nature Reviews Drug Discovery
Volume 21 Issue 5, May 2022
https://www.nature.com/nrd/volumes/21/issues/5

 

Review Article | 16 March 2022
Strategies to access biosynthetic novelty in bacterial genomes for drug discovery
Natural products derived from bacteria are an important source of potential new drug compounds, such as antibiotics and anticancer agents, but how to efficiently mine this resource remains a challenge. In their Review, Hemmerling and Piel discuss newly developed computational tools and strategies to access biosynthetic novelty in bacterial genomes. They consider the opportunities and challenges associated with different bacterial sources, including cultivated, ecology-based and previously untapped bacterial ‘dark matter’.
Franziska Hemmerling, Jörn Piel

Combining rapid diagnostic tests to estimate primary and post-primary dengue immune status at the point of care

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PLoS Neglected Tropical Diseases
http://www.plosntds.org/
(Accessed 07 May 2022)

 

Combining rapid diagnostic tests to estimate primary and post-primary dengue immune status at the point of care
Joseph R. Biggs, Ava Kristy Sy, James Ashall, Marsha S. Santoso, Oliver J. Brady, Mary Anne Joy Reyes, Mary Ann Quinones, William Jones-Warner, Amadou O. Tandoc, Nemia L. Sucaldito, Huynh Kim Mai, Le Thuy Lien, Hung Do Thai, Hien Anh Thi Nguyen, Dang Duc Anh, Chihiro Iwasaki, Noriko Kitamura, Marnix Van Loock, Guillermo Herrera-Taracena, Joris Menten, Freya Rasschaert, Liesbeth Van Wesenbeeck, Sri Masyeni, Sotianingsih Haryanto, Benediktus Yohan, Eva Cutiongco-de la Paz, Lay-Myint Yoshida, Stephane Hue, Maria Rosario Z. Capeding, Carmencita D. Padilla, R. Tedjo Sasmono, Julius Clemence R. Hafalla, Martin L. Hibberd
Research Article | published 04 May 2022 PLOS Neglected Tropical Diseases
https://doi.org/10.1371/journal.pntd.0010365

Which vaccine attributes foster vaccine uptake? A cross-country conjoint experiment

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PLoS One
http://www.plosone.org/
[Accessed 07 May 2022]

 

Which vaccine attributes foster vaccine uptake? A cross-country conjoint experiment
Sabrina Stöckli, Anna Katharina Spälti, Joseph Phillips, Florian Stoeckel, Matthew Barnfield, Jack Thompson, Benjamin Lyons, Vittorio Mérola, Paula Szewach, Jason Reifler
Research Article | published 04 May 2022 PLOS ONE
https://doi.org/10.1371/journal.pone.0266003

A qualitative study of COVID-19 vaccine intentions and mistrust in Black Americans: Recommendations for vaccine dissemination and uptake

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PLoS One
http://www.plosone.org/
[Accessed 07 May 2022]

 

A qualitative study of COVID-19 vaccine intentions and mistrust in Black Americans: Recommendations for vaccine dissemination and uptake
Lu Dong, Laura M. Bogart, Priya Gandhi, James B. Aboagye, Samantha Ryan, Rosette Serwanga, Bisola O. Ojikutu
Research Article | published 03 May 2022 PLOS ONE
https://doi.org/10.1371/journal.pone.0268020

The perceived effectiveness and hidden inequity of postpandemic fiscal stimuli

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PNAS – Proceedings of the National Academy of Sciences of the United States
May 3, 2022 vol. 119 no. 18
https://www.pnas.org/toc/pnas/119/18

 

Sustainability Science
Research Article April 25, 2022 Dataset Open Access
The perceived effectiveness and hidden inequity of postpandemic fiscal stimuli
The world has committed trillions in fiscal expenditures to reboot the economy in the post–COVID-19 era. However, the effectiveness and the equity impacts of current fiscal stimuli are not fully understood. Using an extended adaptive regional input–output …
Yaxin Zhang, Xinzhu Zheng, […]Can Wang

Factors that differentiate COVID-19 vaccine intentions among Indiana parents: Implications for targeted vaccine promotion

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Preventive Medicine
Volume 158 May 2022
https://www.sciencedirect.com/journal/preventive-medicine/vol/158/suppl/C

 

Research article Full text access
Factors that differentiate COVID-19 vaccine intentions among Indiana parents: Implications for targeted vaccine promotion
Katharine J. Head, Gregory D. Zimet, Constantin T. Yiannoutsos, Ross D. Silverman, … Nir Menachemi
Article 107023

Missed routine pediatric care and vaccinations in US children during the first year of the COVID-19 pandemic

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Preventive Medicine
Volume 158 May 2022
https://www.sciencedirect.com/journal/preventive-medicine/vol/158/suppl/C

 

Research article Full text access
Missed routine pediatric care and vaccinations in US children during the first year of the COVID-19 pandemic
Chloe A. Teasdale, Luisa N. Borrell, Yanhan Shen, Spencer Kimball, … Denis Nash
Article 107025

The Impact of COVID-19 Pandemic Lockdown on Routine Immunization in the Province of Laghman, Afghanistan

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Risk Management and Healthcare Policy
https://www.dovepress.com/risk-management-and-healthcare-policy-archive56
[Accessed 07 May 2022]

 

Original Research
The Impact of COVID-19 Pandemic Lockdown on Routine Immunization in the Province of Laghman, Afghanistan
Abid Z, Castro Delgado R, Cernuda Martinez JA, Arcos González P
Risk Management and Healthcare Policy 2022, 15:901-908
Published Date: 5 May 2022

Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa

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Science
Volume 376| Issue 6593| 6 May 2022
https://www.science.org/toc/science/current

 

Research Articles
Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa
BY Juliet R. C. Pulliam, et al.
06 May 2022
Open Access
Analysis of routine surveillance data from South Africa indicates that the Omicron variant of SARS-CoV-2 evades immunity from prior infection.

Standards of Conducts for Biostatisticians and Stem Cell Researchers: A Call for Self-formulated Aspirational Ethics Over Built-in Prohibitive Ethics

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Science and Engineering Ethics
Volume 28, issue 2, April 2022
https://link.springer.com/journal/11948/volumes-and-issues/28-2

 

Original Research/Scholarship – Open Access
Standards of Conducts for Biostatisticians and Stem Cell Researchers: A Call for Self-formulated Aspirational Ethics Over Built-in Prohibitive Ethics
Keiko Sato & Mika Suzuki
Published: 17 March 2022
Abstract
We proposed the Standards of Conducts to provide a general framework that will serve as the basis for guiding each biostatistician and stem cell researcher to formulate their personal standards, rather than as rules with which they are required to comply. Given the responsibility and characteristics of their work, they are expected to maintain independence and work autonomously as professionals. Each of the Standards of Conducts comprises a preamble, mission and values to uphold, Standards of Conducts (10 items), and background. When one internalizes “self-formulated” standards, to make excuses for oneself would be akin to a self-betrayal; responsible actions can be anticipated. If one begins and continues to consider “who I am and what do I work for,” this will become their inner energy, and a source of motivation and pride to inspire oneself. In addition, this aspirational style might help citizens to recognize the autonomous stance of the professional body and that they share the same values.

SIRVA (Shoulder Injury Related to Vaccine Administration) following mRNA COVID-19 Vaccination: Case discussion and literature review

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Vaccine
Volume 40, Issue 18 Pages 2525-2646 (20 April 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/18

 

Review article Full text access
SIRVA (Shoulder Injury Related to Vaccine Administration) following mRNA COVID-19 Vaccination: Case discussion and literature review
Wen Loong Paul Yuen, Sir Young James Loh, Dehao Bryan Wang
Pages 2546-2550

Vaccine events raising public concern and associated immunization program policy and practice changes, China, 2005–2021

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Vaccine
Volume 40, Issue 18 Pages 2525-2646 (20 April 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/18

 

Research article Abstract only
Vaccine events raising public concern and associated immunization program policy and practice changes, China, 2005–2021
Xiaoxue Liu, Wenzhou Yu, Zundong Yin, Lance Rodewald, … Lingsheng Cao
Pages 2561-2567

Healthcare worker perspectives on COVID-19 vaccines: Implications for increasing vaccine acceptance among healthcare workers and patients

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Vaccine
Volume 40, Issue 18 Pages 2525-2646 (20 April 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/18

 

Research article Full text access
Healthcare worker perspectives on COVID-19 vaccines: Implications for increasing vaccine acceptance among healthcare workers and patients
Christine M. Thomas, Kelly Searle, Alma Galván, Amy K. Liebman, … William M. Stauffer
Pages 2612-2618

Efficacy and safety of a quadrivalent influenza vaccine in children aged 6–35 months: A global, multiseasonal, controlled, randomized Phase III study

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Vaccine
Volume 40, Issue 18 Pages 2525-2646 (20 April 2022)
https://www.sciencedirect.com/journal/vaccine/vol/40/issue/18

 

Research article Open access
Efficacy and safety of a quadrivalent influenza vaccine in children aged 6–35 months: A global, multiseasonal, controlled, randomized Phase III study
Susanna Esposito, Jos Nauta, Giulia Lapini, Emanuele Montomoli, Serge van de Witte
Pages 2626-2634